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PTPRN (BC007713) Human Untagged Clone
CAT＃: SC122253
PTPRN (untagged)-Homo sapiens, protein tyrosine phosphatase, receptor type, N, clone MGC:12646 IMAGE:4130827, complete cds
CNY 6,270.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FLJ16131; IA-2; IA-2/PTP; IA2; ICA512; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase-like N; R-PTP-N |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for BC007713 edited
GGCACGAGGGCCAGCTCCTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTG GAGCACCTGCTGCTGCCCCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTG CTGCAGCCCTACCTGTTCCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGC TCCCCAGGGATGGTCAGTGTCGGCCCCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGC AGAACTGCCTCCAAGGGCATATTTGGGGACCACCCTGGCCACTCCTACGGGGACCTTCCA GGGCCTTCACCTGCCCAGCTTTTTCAAGACTCTGGGCTGCTCTATCTGGCCCAGGAGTTG CCAGCACCCAGCAGGGCCAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCCGGGCA GAGGACTCCCCAGAGGGCTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCT TCCCCAGCTGTGCAGCCAGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTAT GGGGTAGAGCTGCGTCAGCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAG CTACTGCCCAAGGGTGCAGGAAGAAATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATC AAGAAAACAATGGAGGGGCCGGTGGAGGGCAGAGACACAGCAGAGCTTCCAGCCCGCACA TCCCCCATGCCTGGACACCCCACTGCCAGCCCTACCTCCAGTGAAGTCCAGCAGGTGCCA AGCCCTGTCTCCTCTGAGCCTCCCAAAGCTGCCAGACCCCCTGTGACACCTGTCCTGCTA GAGAAGAAAAGCCCACTGGGCCAGAGCCAGCCCACGGTGGCAGGACAGCCCTCAGCCCGC CCAGCAGCAGAGGAATATGGCTACATCGTCACTGATCAGAAGCCCCTGAGCCTGGCTGCA GGAGTGAAGCTGCTGGAGATCCTGGCTGAGCATGTGCACATGTCCTCAGGCAGCTTCATC AACATCAGTGTGGTGGGACCAGCCCTCACCTTCCGCATCCGGCACAATGAGCAGAACCTG TCTTTGGCTGATGTGACCCAACAAGCAGGGCTGGTGAAGTCTGAACTGGAAGCACAGACA GGGCTCCAAATCTTGCAGACAGGAGTGGGACAGAGGGAGGAGGCAGCTGCAGTCCTTCCC CAAACTGCGCACAGCACCTCACCCATGCGCTCAGTGCTGCTCACTCTGGTGGCCCTGGCA GGTGTGGCTGGGCTGCTGGTGGCTCTGGCTGTGGCTCTGTGTGTGCGGCAGCATGCGCGG CAGCAAGACAAGGAGCGCCTGGCAGCCCTGGGGCCTGAGGGGGCCCATGGTGACACTACC TTTGAGTACCAGGACCTGTGCCGCCAGCACATGGCCACGAAGTCCTTGTTCAACCGGGCA GAGGGTCCACCGGAGCCTTCACGGGTGAGCAGTGTGTCCTCCCAGTTCAGCGACGCAGCC CAGGCCAGCCCCAGCTCCCACAGCAGCACCCCGTCCTGGTGCGAGGAGCCGGCCCAAGCC AACATGGACATCTCCACGGGACACATGATTCTGGCATACATGGAGGATCACCTGCGGAAC CGGGACCGCCTTGCCAAGGAGTGGCAGGCCCTCTGTGCCTACCAAGCAGAGCCAAACACC TGTGCCACCGCGCAGGGGGAGGGCAACATCAAAAAGAACCGGCATCCTGACTTCCTGCCC TATGACCATGCCCGCATAAAACTGAAGGTGGAGAGCAGCCCTTCTCGGAGCGATTACATC AACGCCAGCCCCATTATTGAGCATGACCCTCGGATGCCAGCCTACATAGCCACGCAGGGC CCGCTGTCCCATACCATCGCAGACTTCTGGCAGATGGTGTGGGAGAGCGGCTGCACCGTC ATCGTCATGCTGACCCCGCTGGTGGAGGATGGTGTCAAGCAGTGTGACCGCTACTGGCCA GATGAGGGTGCCTCCCTCTACCACGTATATGAGGTGAACCTGGTGTCGGAGCACATCTGG TGCGAGGACTTTCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGC ACGCTCACGCAGTTCCACTTCCTCAGCTGGCCGGCAGAGGGCACACCGGCCTCCACGCGG CCCCTGCTGGACTTCCGCAGGAAGGTGAACAAGTGCTACCGGGGCCGCTCCTGCCCCATC ATCGTGCACTGCAGTGATGGTGCGGGGAGGACCGGCACCTACATCCTCATCGACATGGTC CTGAACCGCATGGCAAAAGGAGTGAAGGAGATTGACATCGCTGCCACCCTGGAGCATGTC CGTGACCAGCGGCCTGGCCTTGTCCGCTCTAAGGACCAGTTTGAATTTGCCCTGACAGCC GTGGCGGAGGAAGTGAATGCCATCCTCAAGGCCCTGCCCCAGTGAGACCCTGGGGCCCCT TGGCGGGCAGCCCAGCCTCTGTCCCTCTTTGCCTGTGTGAGCATCTCTGTGTACCCACTC CTCACTGCCCCACCAGCCACCTCTTGGGCATGCTCAGCCCTTCCTAGAAGAGTCAGGAAG GGAAAGCCAGAAGGGGCACGCCTGCCCAGCCTCGCATGCCAGAGCCTGGGGCATCCCAGA GCCCAGGGCATCCCATGGGGGTGCTGCAGCCAGGAGGAGAGGAAAGGACATGGGTAGCAA TTCTACCCAGAGCCTTCTCCTGCCTACATTCCCTGGCCTGGCTCTCCTGTAGCTCTCCTG GGGTTCTGGGAGTTCCCTGAACATCTGTGTGTGTCCCCCTATGCTCCAGTATGGAAGAAT GGGGTGGAGGGTCGCCACACCCGGCTCCCCCTGCTTCTCAGCCCCGGGCCTGCCTCTGAC TCACACTTGGGCGCTCTGCCCTCCCTGGCCTCACGCCCAGCCTCCTCCCACCACCCTCCC ACCATGCGCTGCTCAACCTCTCTCCTTCTGGCGCAAGAGAACATTTCTAGAAAAAACTAC TTTTGTACCAGTGTGAATAAAGTTAGTGTGTTGTCTGTGCAGCTGCAAAAAAAAAAAAAA AAAAA >OriGene 5' read for BC007713 unedited
NGGTTCAGATTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGGCCAGCTC CTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTGGAGCACCTGCTGCTGCC CCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTGCTGCAGCCCTACCTGTT CCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGCTCCCCAGGGATGGTCAG TGTCGGCCCCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGCAGAACTGCCTCCAAGGG CATATTTGGGGACCACCCTGGCCACTCCTACGGGGACCTTCCAGGGCCTTCACCTGCCCA GCTTTTTCAAGACTCTGGGCTGCTCTATCTGGCCCAGGAGTTGCCAGCACCCAGCAGGGC CAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCCGGGCAGAGGACTCCCCAGAGGG CTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCTTCCCCAGCTGTGCAGCC AGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTATGGGGTAGAGCTGCGTCA GCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAGCTACTGCCCAAGGGTGC ANGAAGAAATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATCAAGAAAACAATGGAGGG GCCGGTGGAGGGCAAANACACAGCAGAGCTTCCAGCCCGCACATCCCCCATGCCTGGACA CCCCACTGCCAGCCCTACCTCCAGTGAAGTCCCAGCAGTGCCAAGCCCTGTCTCCTCTGA GCCTCCAAAGCTGCCAGACCCCTGTGACACCTGTCCTGCTAGAGAAGAAAAGCCACTGGG CCAAC |
| Restriction Sites | Please inquire |
| ACCN | BC007713 |
| Insert Size | 3065 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC007713.1, AAH07713.1 |
| RefSeq Size | 3065 bp |
| Locus ID | 5798 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Type I diabetes mellitus |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010] |
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