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glucose 6 phosphatase, catalytic subunit (G6PC) (NM_000151) Human Untagged Clone
CAT＃: SC120076
G6PC (untagged)-Human glucose-6-phosphatase, catalytic subunit (G6PC)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | G6Pase; G6PC; G6PT; GSD1; GSD1a |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC120076 sequence for NM_000151 edited (data generated by NextGen Sequencing)
ATGGAGGAAGGAATGAATGTTCTCCATGACTTTGGGATCCAGTCAACACATTACCTCCAG GTGAATTACCAAGACTCCCAGGACTGGTTCATCTTGGTGTCCGTGATCGCAGACCTCAGG AATGCCTTCTACGTCCTCTTCCCCATCTGGTTCCATCTTCAGGAAGCTGTGGGCATTAAA CTCCTTTGGGTAGCTGTGATTGGAGACTGGCTCAACCTCGTCTTTAAGTGGATTCTCTTT GGACAGCGTCCATACTGGTGGGTTTTGGATACTGACTACTACAGCAACACTTCCGTGCCC CTGATAAAGCAGTTCCCTGTAACCTGTGAGACTGGACCAGGGAGCCCCTCTGGCCATGCC ATGGGCACAGCAGGTGTATACTACGTGATGGTCACATCTACTCTTTCCATCTTTCAGGGA AAGATAAAGCCGACCTACAGATTTTGGTGCTTGAATGTCATTTTGTGGTTGGGATTCTGG GCTGTGCAGCTGAATGTCTGTCTGTCACGAATCTACCTTGCTGCTCATTTTCCTCATCAA GTTGTTGCTGGAGTCCTGTCAGGCATTGCTGTTGCAGAAACTTTCAGCCACATCCACAGC ATCTATAATGCCAGCCTCAAGAAATATTTTCTCATTACCTTCTTCCTGTTCAGCTTCGCC ATCGGATTTTATCTGCTGCTCAAGGGACTGGGTGTAGACCTCCTGTGGACTCTGGAGAAA GCCCAGAGGTGGTGCGAGCAGCCAGAATGGGTCCACATTGACACCACACCCTTTGCCAGC CTCCTCAAGAACCTGGGCACGCTCTTTGGCCTGGGGCTGGCTCTCAACTCCAGCATGTAC AGGGAGAGCTGCAAGGGGAAACTCAGCAAGTGGCTCCCATTCCGCCTCAGCTCTATTGTA GCCTCCCTCGTCCTCCTGCACGTCTTTGACTCCTTGAAACCCCCATCCCAAGTCGAGCTG GTCTTCTACGTCTTGTCCTTCTGCAAGAGTGCGGTAGTGCCCCTGGCATCCGTCAGTGTC ATCCCCTACTGCCTCGCCCAGGTCCTGGGCCAGCCGCACAAGAAGTCGTTGTAA Clone variation with respect to NM_000151.2 445 c=>t;574 a=>g >OriGene 5' read for NM_000151 unedited
GCATATGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGACCACCAAGCCTG GATAACTGCAGGGCTCTGCTGACATCTTCCTGAGGTGCCAAGGAAATGAGGATGGAGGAA GGAATGAATGTTCTCCATGACTTTGGGATCCAGTCAACACATTACCTCCAGGTGAATTAC CAAGACTCCCAGGACTGGTTCATCTTGGTGTCCGTGATCGCAGACCTCAGGAATGCCTTC TACGTCCTCTTCCCCATCTGGTTCCATCTTCAGGAAGCTGTGGGCATTAAACTCCTTTGG GTAGCTGTGATTGGAGACTGGCTCAACCTCGTCTTTAAGTGGATTCTCTTTGGACAGCGT CCATACTGGTGGGTTTTGGATACTGACTACTACAGCAACACTTCCGTGCCCCTGATAAAG CAGTTCCCTGTAACCTGTGAGACTGGACCAGGGAGCCCCTCTGGCCATGCCATGGGCACA GCAGGTGTATACTACGTGATGGTCACATCTACTCTTTCCATCTTTCAGGGAAAGATAAAG CCGACCTACAGATTTTGGTGCTTGAATGTCATTTTGTGGTTGGGATTCTGGGCTGTGCAG CTGAATGTCTGTCTGTCACGAATCTACCTTGCTGCTCATTNTCCTCATCAAGTTGTTGCT GGAGTCCTGTCAGGCATTGCTGTTGCAGAAACTTTCAGCCACATCCACAGCATCTATAAT GCCAGCCTCAAGAAATATTTCTCATTACCTTNCTCCTGTTCAGCTTCGCCATCGGATTNT ATCTGCTGCTCAGGGACTGGGTGTAGACCTCCTGTGGACTCTGCAGAAAGCCCCCAGTGG TGCGAGCAGCCAGAATGGGTCCCATTGACACACACCTTTGCCAGCCCCTCAAGACCTGGC ACGCTCTTTGCCTGGGCCTGCTCTCACTCCCCTGTCAAGGAGAGCGCAGGNGAACTA >OriGene 3' read for NM_000151 unedited
AGTTTGGCCGCGGCCGCAATCNANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTATAGGAATTAACAAGACGTGATTCTTAAATAAAATGTTGCTTTAATAAAATACT GCACATATATATTTTTCTTTTCAAAGATGTTATGAGCAGGATGGTTGTTTTGAATGATAA TGTATGGTATACTATATAATTAGTAGCAAAAACAAGGACTTTCAAATAAATAGGCTTCAT CTTTTTTTGGGGGGTAGGTGGGTGGGGCAAAAATACTCTGCATATCAGATGAAATTGAAA AACAGGCAAGGAGGGCCCGGTGCGGGGGCTCATGCCTGTAATCCTAGCACCTTGGGAGGC CAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGATGAAA TCCCATCTCTTCTAAAAATATAAAAATTAGCCTGGCATGGTGGTGCACGCCGGTAGTCCT AGCTACTGAGGAGGCTGAGACATGAGAATCGCTTGAACCAGGAGGAAGAGGTTGCAGTGA GCCAAGATCGTGCCACTCCACTCCAGCCTGGGTGATAGGTGCGCCGTCTCAAAAAAAGAA AAAAAAAGAAAAGCAGGCAAGGAGGAGTTGGCTAGCTGGACATAGTGGCTTGCACCTGTA GTCCCAGCTACGCGGGACGCTGTGGTATGGTGGGAGGACTGCTTGAGCCCANGAATTCAG AGCAGCCTGGGCAACATAGTGAGACCCTGTCTCAAAAAAAAAAAAAAGAGAGAGAATGTG ACTTTTCCTTTAAAATGTGCTCTTGGNTGGCCTTGGGATAAAGAAAGGATTCTATTTTAC CCTCTAGGAATAAAAGTTACACTGGAATGACCTGAAAAAGGATTCTGGNCCTCCCCTTGA ATTTTGCCAACAATTCAGACCCTATTGGAACTACAAAGCCCCACGGGTCGCCTCTAGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000151 |
| Insert Size | 3110 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000151.1, NP_000142.1 |
| RefSeq Size | 3095 bp |
| RefSeq ORF | 1074 bp |
| Locus ID | 2538 |
| UniProt ID | P35575 |
| Domains | acidPPc |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Adipocytokine signaling pathway, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism |
| Gene Summary | Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215623 | G6PC (Myc-DDK-tagged)-Human glucose-6-phosphatase, catalytic subunit (G6PC) |
CNY 3,656.00 |
|
| RC215623L1 | Lenti ORF clone of Human glucose-6-phosphatase, catalytic subunit (G6PC), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215623L2 | Lenti ORF clone of Human glucose-6-phosphatase, catalytic subunit (G6PC), mGFP tagged |
CNY 5,890.00 |
|
| RC215623L3 | Lenti ORF clone of Human glucose-6-phosphatase, catalytic subunit (G6PC), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215623L4 | Lenti ORF clone of Human glucose-6-phosphatase, catalytic subunit (G6PC), mGFP tagged |
CNY 5,890.00 |
|
| RG215623 | G6PC (tGFP-tagged) - Human glucose-6-phosphatase, catalytic subunit (G6PC) |
CNY 4,370.00 |
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