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PRPH2 (NM_000322) Human Untagged Clone
CAT＃: SC119972
PRPH2 (untagged)-Human peripherin 2 (retinal degeneration, slow) (PRPH2)
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AOFMD; AVMD; CACD2; DS; MDBS1; PRPH; rd2; RDS; RP7; TSPAN22 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119972 sequence for NM_000322 edited (data generated by NextGen Sequencing)
ATGGCGCTACTGAAAGTCAAGTTTGACCAGAAGAAGCGGGTCAAGTTGGCCCAAGGGCTC TGGCTCATGAACTGGTTCTCCGTGTTGGCTGGCATCATCATCTTCAGCCTAGGACTGTTC CTGAAGATTGAACTCCGAAAGAGGAGCGATGTGATGAATAATTCTGAGAGCCATTTTGTG CCCAACTCATTGATAGGGATGGGGGTGCTATCCTGTGTCTTCAACTCGCTGGCTGGGAAG ATCTGCTACGACGCCCTGGACCCAGCCAAGTATGCCAGATGGAAGCCCTGGCTGAAGCCG TACCTGGCTATCTGTGTCCTCTTCAACATCATCCTCTTCCTTGTGGCTCTCTGCTGCTTT CTGCTTCGGGGCTCGCTGGAGAACACCCTGGGCCAAGGGCTCAAGAACGGCATGAAGTAC TACCGGGACACAGACACCCCTGGCAGGTGTTTCATGAAGAAGACCATCGACATGCTGCAG ATCGAGTTCAAATGCTGCGGCAACAACGGTTTTCGGGACTGGTTTGAGATTCAGTGGATC AGCAATCGCTACCTGGACTTTTCCTCCAAAGAAGTCAAAGATCGAATCAAGAGCAACGTG GATGGGCGGTACCTGGTGGACGGCGTCCCTTTCAGCTGCTGCAATCCTAGCTCGCCACGG CCCTGCATCCAGTATCAGATCACCAACAACTCAGCACACTACAGTTACGACCACCAGACG GAGGAGCTCAACCTGTGGGTGCGTGGCTGCAGGGCTGCCCTGCTGAGCTACTACAGCAGC CTCATGAACTCCATGGGTGTCGTCACGCTCCTCATTTGGCTCTTCGAGGTGACCATTACA ATTGGGCTGCGCTACCTACAGACGTCGCTGGATGGTGTGTCCAACCCCGAGGAATCTGAG AGCGAGAGCGAGGGCTGGCTGCTGGAGAAGAGCGTGCCGGAGACCTGGAAGGCCTTTCTG GAGAGTGTGAAGAAGCTGGGCAAGGGCAACCAGGTGGAAGCCGAGGGCGCAGGCGCAGGC CAGGCCCCAGAGGCTGGCTGA Clone variation with respect to NM_000322.4 318 t=>c;910 c=>g;929 g=>a;1013 a=>g >OriGene 5' read for NM_000322 unedited
ATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCATGGCGCTACT GAAAGTCAAGTTTGACCAGAAGAAGCGGGTCAAGTTGGCCCAGGGCTCTGGCTCATGAAC TGGTTCTCCGTGTTGGCTGGCATCATCATCTTCAGCCTAGGACTGTTCCTGAAGATTGAA CTCCGAAAGAGGAGCGATGTGATGAATAATTCTGAGAGCCATTTTGTGCCCAACTCATTG ATAGGGATGGGGGTGCTATCCTGTGTCTTCAACTCGCTGGCTGGGAAGATCTGCTACGAC GCCCTGGACCCAGCCAAGTATGCCAGATGGAAGCCCTGGCTGAAGCCGTACCTGGCTATC TGTGTCCTCTTCAACATCATCCTCTTCCTTGTGGCTCTCTGCTGCTTTCTGCTTCGGGGC TCGCTGGAGAACACCCTGGGCCAAGGGCTCAAGAACGGCATGAAGTACTACCGGGACACA GACACCCCTGNGCAGGTGTTTCATGAAGAAGACCATCGACATGCCTGCAGATCGAGTTCA AATGCTGCGGAACAACGGTTTTCGGGAACTGGTTTGGNAATTCAGTGGATCAGCAATCGC TACCTGNACTTTTCCTCCAAAGAGTCAAAGAGTTGCAGGATGAGCAAGCTGGCAGTGTCT TTTGGGTGNGAGAGGTANAAACATGCGGGAGCTCAGACATTNTTGGAACCAGAACTACCA CCCCAGAGGCCACCCTGTGGGGTTCCCATCCTGGAGGGGAAAAGCTGGCACCAGCTCTTG CTCTTCACATTCTTCCCAGGACCCCAGACTACGTCATAGACACCNGGTGTGGGGGCGCCT CTTGGGGGGGACGGCGTCTTTTAGTGCTGCATCTACTCGCACGCCTGATCN >OriGene 3' read for NM_000322 unedited
TTTTNNAATTTTTCTTGAACCGCGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTCCATACAGNATGAATTTTAATTATCTATTGACAGCTGTTAACAG CATAGTTACACTTGGGGGCCTAAAGCAGCACTTTCACCGGGGTTCTCAGCACTCTTGAAA GATAGCAAGAGCTCAGGGACCTTTGCCAAAAATGGCTGGCTCAGCATTTTTTCAGTATGG ATCATTCCTTGGCCTCAACGAGATTCAAAAATCTAATTAAACTTGGGACCAACGTCTGAC AGGGTGTCCAAACATCTTGGATCTGGTCTTCTGCTTGGGGGAATTAAGCCCAGAACATAC CCCAGCAGCACCAGAAGTCTTATTTTCTCTACACTAAAGTTCTTAGGACAGCAAAGACCC CAACTCAGTCCAAAGTACCTATTCCCAAACACCATCGTCAAAGCAGAGGTAAGTATGGAC TGTTCCCTTTCTGGTTTTGCCTTTTGCCCTGGGCTCCAGCCAGTAAGAACGAGCTCTCTG AATGTCATCCAACTGGAGGAATATGCTGGGCCCTGCCTTGGTTGGGCACCAAGGGCTTGG GAAATCACCAAATCTTCTTTTCCTTCCCCTGAAAACTTTTTTTTCTAAAGAAAGGGAAAC CTCCTGTTTTGGCTGCCTACGAAAAAGGGCCTTTCCAAAAGATTTCCTTTGATGCCAAAG CATTCCAAAAATAGGGTTTTTAAAAAGGGTTCTTGGGGGGAAAAAACGAGAAAACCCCCA AAGAATTCTTGCCCCTTGTGGGGAACATAATGGTGCCCTGGGGCTGGAGGCACCTTGGGG GGGGCCCTGGCCCCCAAAACGAGGCCGGGTCCAAAGGGGAACCAGGGGAAGGGGCGCCTT TCCAAGGGGGAAAACTACCCCTGTTTCCCGAAACCAGGAAAACCGCCTTGGGGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000322 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000322.2, NP_000313.1 |
| RefSeq Size | 2974 bp |
| RefSeq ORF | 1041 bp |
| Locus ID | 5961 |
| UniProt ID | P23942 |
| Domains | transmembrane4 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS) |
| Gene Summary | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210357 | PRPH2 (Myc-DDK-tagged)-Human peripherin 2 (retinal degeneration, slow) (PRPH2) |
CNY 3,656.00 |
|
| RC210357L1 | Lenti ORF clone of Human peripherin 2 (retinal degeneration, slow) (PRPH2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210357L2 | Lenti ORF clone of Human peripherin 2 (retinal degeneration, slow) (PRPH2), mGFP tagged |
CNY 5,890.00 |
|
| RC210357L3 | Lenti ORF clone of Human peripherin 2 (retinal degeneration, slow) (PRPH2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210357L4 | Lenti ORF clone of Human peripherin 2 (retinal degeneration, slow) (PRPH2), mGFP tagged |
CNY 5,890.00 |
|
| RG210357 | PRPH2 (tGFP-tagged) - Human peripherin 2 (retinal degeneration, slow) (PRPH2) |
CNY 4,370.00 |
