Protein S (PROS1) (NM_000313) Human Untagged Clone

CAT#: SC119963

PROS1 (untagged)-Human protein S (alpha) (PROS1)



  "NM_000313" in other vectors (6)

CNY 4,960.00


货期*
现货

规格
    • 10 ug

Cited in 1 publication.

Product images

经常一起买 (4)
Anti-PROS1 Rabbit Polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms PROS; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119963 sequence for NM_000313 edited (data generated by NextGen Sequencing)
ATGAGGGTCCTGGGTGGGCGCTGCGGGGCGCTGCTGGCGTGTCTCCTCCTAGTGCTTCCC
GTCTCAGAGGCAAACTTTTTGTCAAAGCAACAGGCTTCACAAGTCCTGGTTAGGAAGCGT
CGTGCAAATTCTTTACTTGAAGAAACCAAACAGGGTAATCTTGAAAGAGAATGCATCGAA
GAACTGTGCAATAAAGAAGAAGCCAGGGAGGTCTTTGAAAATGACCCGGAAACGGATTAT
TTTTATCCAAAATACTTAGTTTGTCTTCGCTCTTTTCAAACTGGGTTATTCACTGCTGCA
CGTCAGTCAACTAATGCTTATCCTGACCTAAGAAGCTGTGTCAATGCCATTCCAGACCAG
TGTAGTCCTCTGCCATGCAATGAAGATGGATATATGAGCTGCAAAGATGGAAAAGCTTCT
TTTACTTGCACTTGTAAACCAGGTTGGCAAGGAGAAAAGTGTGAATTTGACATAAATGAA
TGCAAAGATCCCTCAAATATAAATGGAGGTTGCAGTCAAATTTGTGATAATACACCTGGA
AGTTACCACTGTTCCTGTAAAAATGGTTTTGTTATGCTTTCAAATAAGAAAGATTGTAAA
GATGTGGATGAATGCTCTTTGAAGCCAAGCATTTGTGGCACAGCTGTGTGCAAGAACATC
CCAGGAGATTTTGAATGTGAATGCCCCGAAGGCTACAGATATAATCTCAAATCAAAGTCT
TGTGAAGATATAGATGAATGCTCTGAGAACATGTGTGCTCAGCTTTGTGTCAATTACCCT
GGAGGTTACACTTGCTATTGTGATGGGAAGAAAGGATTCAAACTTGCCCAAGATCAGAAG
AGTTGTGAGGTTGTTTCAGTGTGCCTTCCCTTGAACCTTGACACAAAGTATGAATTACTT
TACTTGGCGGAGCAGTTTGCAGGGGTTGTTTTATATTTAAAATTTCGTTTGCCAGAAATC
AGCAGATTTTCAGCAGAATTTGATTTCCGGACATATGATTCAGAAGGCGTGATACTGTAC
GCAGAATCTATCGATCACTCAGCGTGGCTCCTGATTGCACTTCGTGGTGGAAAGATTGAA
GTTCAGCTTAAGAATGAACATACATCCAAAATCACAACTGGAGGTGATGTTATTAATAAT
GGTCTATGGAATATGGTGTCTGTGGAAGAATTAGAACATAGTATTAGCATTAAAATAGCT
AAAGAAGCTGTGATGGATATAAATAAACCTGGACCCCTTTTTAAGCCGGAAAATGGATTG
CTGGAAACCAAAGTATACTTTGCAGGATTCCCTCGGAAAGTGGAAAGTGAACTCATTAAA
CCGATTAACCCTCGTCTAGATGGATGTATACGAAGCTGGAATTTGATGAAGCAAGGAGCT
TCTGGAATAAAGGAAATTATTCAAGAAAAACAAAATAAGCATTGCCTGGTTACTGTGGAG
AAGGGCTCCTACTATCCTGGTTCTGGAATTGCTCAATTTCACATAGATTATAATAATGTA
TCCAGTGCTGAGGGTTGGCATGTAAATGTGACCTTGAATATTCGTCCATCCACGGGCACT
GGTGTTATGCTTGCCTTGGTTTCTGGTAACAACACAGTGCCCTTTGCTGTGTCCTTGGTG
GACTCCACCTCTGAAAAATCACAGGATATTCTGTTATCTGTTGAAAATACTGTAATATAT
CGGATACAGGCCCTAAGTCTATGTTCCGATCAACAATCTCATCTGGAATTTAGAGTCAAC
AGAAACAATCTGGAGTTGTCGACACCACTTAAAATAGAAACCATCTCCCATGAAGACCTT
CAAAGACAACTTGCCGTCTTGGACAAAGCAATGAAAGCAAAAGTGGCCACATACCTGGGT
GGCCTTCCAGATGTTCCATTCAGTGCCACACCAGTGAATGCCTTTTATAATGGCTGCATG
GAAGTGAATATTAATGGTGTACAGTTGGATCTGGATGAAGCCATTTCTAAACATAATGAT
ATTAGAGCTCACTCATGTCCGTCAGTTTGGAAAAAGACAAAGAATTCTTAA

Clone variation with respect to NM_000313.3
2001 a=>g
>OriGene 5' read for NM_000313 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGGGTCGCTGGCGCCG
CCGCGCAGCACGGCTCAGACCGAGGCGCACAGGCTCGCAGCTCCGCGGCGCCTAGCGCTC
CGGTCCCCGCCGCGACGCGCCACCGTCCCTGCCGGCGCCTCCGCGCGCTTCGAAATGAGG
GTCCTGGGTGGGCGCTGCGGGGCGCTGCTGGCGTGTCTCCTCCTAGTGCTTCCCGTCTCA
GAGGCAAACTTTTTGTCAAAGCAACAGGCTTCACAAGTCCTGGTTAGGAAGCGTCGTGCA
AATTCTTTACTTGAAGAAACCAAACAGGGTAATCTTGAAAGAGAATGCATCGAAGAACTG
TGCAATAAAGAAGAAGCCAGGGAGGTCTTTGAAAATGACCCGGAAACGGATTATTTTTAT
CCAAAATACTTAGTTTGTCTTCGCTCTTTTCAAACTGGGTTATTCACTGCTGCACGTCAG
TCAACTAATGCTTATCCTGACCTAAGAAGCTGTGTCAATGCCATTCCAGACCAGTGTAGT
CCTCTGCCATGCAATGAAGATGGATATATGAGCTGCAAAGATGGAAAAGCTTCTTTTACT
TGCACTTGTAAACCAGGTTGGCAAGGAGAAAAGTGTGAATTTGACATAAATGAATGCAAA
GATCCCTCAAATATAAATGGAGGTTGCAGTCAAATTTGTGATAATACACCTGGAAGTTAC
CACTGTTCCCTGTAAAATGGTTTTGTTATGCTTTCCAATAAGAAAGATTGTAAAGATGTG
GATGAATGCTCTTTGAAGCCAAGCATTTGTGGCACAGCTGTGTGCAAGACATCCCCAGAG
ATTTTGATGTGAATGCCCCGAAGCTACAGAATNATCTCAAACANAGTCTTGTGAAGAATA
GATGATGCTCTGAGACATGTGTGCTCAGCTTTGGTCACTC
>OriGene 3' read for NM_000313 unedited
GGGGAANNNGGGGCTACTGTGNACCGCGGNCCGCTATTTNANGATCGAGTTTTTTTTTTT
TTTTTTTTAAATTCATATTTAATAGACCACCATCTCTTCTGCCTTCATCAGGAAAAAAAC
AAAAACATAAACAAAATAGTATCTGCCTATGATTAATAGTATTTAATTACACGCACTTTT
GTTTGAGTTTACTTCCTTGCTTTCTGAAAAAAACATAGGTATTTAGACACTAGTTCATGA
TGATAAAATTAAAATTTAGTTTTACAAACAAAAATTGAAACTGTCATTTGTAGGAAAAAA
ATTCAAATTTAAAATTGTTATTTTTCACTATTCTTAGATAGCAAGAGAAGTAAGAATTTC
TTTACTGTGATTTATATCACAACAGAATTTTTTTTCCTTGACAAAGGACCTTTTTAAAAA
TCCCAGAAAAGGACCACAAAATAATCAAAGACTGCACATTGTAAATAAAACCCTTCAGCT
GGTATTGAAACATAAGTATATTTACACACAGAGAAAAGGTATTATAAGCAGAGAAAAGAT
GCCTTAAAAATCTTTGTCTTTTTCCAACTGACGACATGAGTGAGCTCTATTATCATATGT
TTAAAATGGGTTTATCAGATCCAACTGTACACCATAAATTCACTTCCATGCCACCCTTAT
AAAGGATTCACTGGGGTGGACTTGATGGACATCTGGAAGGCCCCCCAGTTTGGGGCCCCT
TTTGTTTTATTGGTTGGCCAAAAACGGAAATGGGTTTTAAGGTCTTATGGGAAAGGGGTT
CTTTTTTAAGGGGGGCCAAACCCCCAAATGTTCTGGTGGCCTTAAATTCCAAAAAAAATG
GTGGTCGAAAAATAACCTAGGGCCGGTTTCCAATTTTTAAAGTTTTTTCAACAAAAAAAA
AATCCTGGATTTTTAAAGGGGGGGTCCCCAAGGACCAACAAGGGCCCTGGTTTTCCCCAA
ACCAGGGGGGTTAAACACGGGCGGG
Restriction Sites NotI-NotI     
ACCN NM_000313
Insert Size 2920 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_000313.1, NP_000304.1
RefSeq Size 3309 bp
RefSeq ORF 2031 bp
Locus ID 5627
UniProt ID P07225
Domains GLA, LamG, EGF_CA, EGF, EGF
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Complement and coagulation cascades
Gene Summary This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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