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MVK (NM_000431) Human Untagged Clone
CAT＃: SC119883
MVK (untagged)-Human mevalonate kinase (MVK), transcript variant 1
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LRBP; MK; MVLK; POROK3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000431 edited
CGCACGAGGGGAGTTGGGGAGCTGCTCCGGCTTCGGCGCGGAGGGGCGGCGGCCGGGGAG GCGGCGGCGGCGGCAGGATTCCCAGGAGCCATGTTGTCAGAAGTCCTACTGGTGTCTGCT CCGGGGAAAGTCATCCTTCATGGAGAACATGCCGTGGTACATGGCAAGGTAGCACTGGCT GTATCCTTGAACTTGAGAACATTCCTCCGGCTTCAACCCCACAGCAATGGGAAAGTGGAC CTCAGCTTACCCAACATTGGTATCAAGCGGGCCTGGGATGTGGCCAGGCTTCAGTCACTG GACACAAGCTTTCTGGAGCAAGGTGATGTCACAACACCCACCTCAGAGCAAGTGGAGAAG CTAAAGGAGGTTGCAGGCTTGCCTGACGACTGTGCTGTCACCGAGCGCCTGGCTGTGCTG GCCTTTCTTTACTTATACCTGTCCATCTGCCGGAAGCAGAGGGCCCTGCCGAGCCTGGAT ATCGTAGTGTGGTCGGAGCTGCCCCCCGGGGCGGGCTTGGGCTCCAGCGCCGCCTACTCG GTGTGTCTGGCAGCAGCCCTCCTGACTGTGTGCGAGGAGATCCCAAACCCGCTGAAGGAC GGGGATTGCGTCAACAGGTGGACCAAGGAGGATTTGGAGCTAATTAACAAGTGGGCCTTC CAAGGGGAGAGAATGATTCACGGGAACCCCTCCGGAGTGGACAATGCTGTCAGCACCTGG GGAGGAGCCCTCCGATACCATCAAGGGAAGATTTCATCCTTAAAGAGGTCGCCAGCTCTC CAGATCCTGCTGACCAACACCAAAGTCCCTCGCAATACCAGGGCCCTTGTGGCTGGCGTC AGAAACAGGCTGCTCAAGTTCCCAGAGATCGTGGCCCCCCTCCTGACCTCAATAGATGCC ATCTCCCTGGAGTGTGAGCGCGTGCTGGGAGAGATGGGGGAAGCCCCAGCCCCGGAGCAG TACCTCGTGCTGGAAGAGCTCATTGACATGAACCAGCACCATCTGAATGCCCTCGGCGTG GGCCACGCCTCTCTGGACCAGCTCTGCCAGGTGACCAGGGCCCGCGGACTTCACAGCAAG CTGACTGGCGCAGGCGGTGGTGGCTGTGGCATCACACTCCTCAAGCCAGGGCTGGAGCAG CCAGAAGTGGAGGCCACGAAGCAGGCCCTGACCAGCTGTGGCTTTGACTGCTTGGAAACC AGCATCGGTGCCCCCGGCGTCTCCATCCACTCAGCCACCTCCCTGGACAGCCGAGTCCAG CAAGCCCTGGATGGCCTCTGAGAGGAGCCCACGACACTGCAGCCCCACCCAGATGCCCCT TTCTGGATTATTCTGGGGGCTGCAGTTCGACTCTGTGCTGGCCAGCGAGCGCCCAGCTCC TGACACTGCTGGAGAGGCCCCAGCCGCTTGGCGATGCCAGCCAAGCTCTGCAGTCCCAGC GGTGGGACCTAGGGAGGCATGGTCTGCCCTCTGCATCCTCTGGAGCCAGCCGAGCAGGAG GCCTAGGAGGGTCCTCTGAGACTCCAGACCTGAGGCGAGAAGGGCTGCTTCCCTGAAGCT CCCACAGTCCCATCTGCTTCAGGCCCCCGCCTTGGCCTGTGTTCTTCCTGGCCGCCTGGG TCCAATGCTCAGGTGCTGGGGCCTGGTTCCCGGAGAAGTGTGCCTTCTCTCTCCCTTTTC AGGGACCGCCCCCTGTCTCTCAGGGCCAGGCCTCTCCCTCCTCCAGGAAGCCTTCCCCTA CCCCTTGTCGCCCCTCCCTCCCAGAGCACCTGCTGTCTGGGTGGCTCACTCAGCACTTGG TGTGGCCTTCCCTTCTACCTAGCGGGATGGGGCTCCCCCAGGGGCTGTCCCGGAGGCGGT GGGCCTGGTTAAATAAGGCAGGGTTTATATGCACTTTCTTCCGATCTGTACCTGAGAGGT TTGTGGAAAAGATGGCAAATGGGGAATAAAAAGATTTTGTGTCAAAAAAAAAAAAAAAAA AAC >OriGene 5' read for NM_000431 unedited
NGGGTCAAAATTTGTATACGACTCCTATAGGCGGCNCGCGAATTCGCACGAGGGGAGTTG GGGAGCTGCTCCGGCTTCGGCGCGGAGGGGCGGCGGCCGGGGAGGCGGCGGCGGCGGCAG GATTCCCAGGAGCCATGTTGTCAGAAGTCCTACTGGTGTCTGCTCCGGGGAAAGTCATCC TTCATGGAGAACATGCCGTGGTACATGGCAAGGTAGCACTGGCTGTATCCTTGAACTTGA GAACATTCCTCCGGCTTCAACCCCACAGCAATGGGAAAGTGGACCTCAGCTTACCCAACA TTGGTATCAAGCGGGCCTGGGATGTGGCCAGGCTTCAGTCACTGGACACAAGCTTTCTGG AGCAAGGTGATGTCACAACACCCACCTCAGAGCAAGTGGAGAAGCTAAAGGAGGTTGCAG GCTTGCCTGACGACTGTGCTGTCACCGAGCGCCTGGCTGTGCTGGCCTTTCTTTACTTAT ACCTGTCCATCTGCCGGAAGCAGAGGGCCCTGCCGAGCCTGGATATCGTAGTGTGGTCGG AGCTGCCCCCCGGGGCGGGCTTGGGCTCCAGCGCCGCCTACTCGGTGTGTCTGGCAGCAG CCCTCCTGACTGTGTGCGAGGAGATCCCAAACCCGCTGAAGGACGGGGATTGCGTCAACA GGTGGACCAAGGAGGATTTGGAGCTAATTAACAAGTGGGCCTTCCAAGGGGAGAGAATGA TTCACGGGAACCCCTCCGGAGTGGACAATGCTGTCAGCACCTGGNGGAGGAGCCCTCCGA TACCATCAAGGGAAGATTTCATCCTTTAAGAGGTCGCCAGCTCTTCCAGATCCTGCTGAC CAACACCAAAGTCCCTCGCATACCAGGCCCCTTGTGGNCTGGCGTCAGAAACAGCTGCTC AAGTCCCNNAGNACGTGCCCCCCT >OriGene 3' read for NM_000431 unedited
TATGGCCGCGGCCGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTTGACACAAAATCT TTTTATTCCCCATTTGCCATCTTTTCCACAAACCTCTCAGGTACAGATCGGAAGAAAGTG CATATAAACCCTGCCTTATTTAACCAGGCCCACCGCCTCCGGGACAGCCCCTGGGGGAGC CCCATCCCGCTAGGTAGAAGGGAAGGCCACACCAAGTGCTGAGTGAGCCACCCAGACAGC AGGTGCTCTGGGAGGGAGGGGCGACAAGGGGTAGGGGAAGGCTTCCTGGAGGAGGGAGAG GCCTGGCCCTGAGAGACAGGGGGCGGTCCCTGAAAAGGGAGAGAGAAGGCACACTTCTCC GGGAACCAGGCCCCAGCACCTGAGCATTGGACCCAGGCGGCCAGGAAGAACACAGGCCAA GGCGGGGGCCTGAAGCAGATGGGACTGTGGGAGCTTCAGGGAAGCAGCCCTTCTCGCCTC AGGTCTGGAGTCTCAGAGGACCCTCCTAGGCCTCCTGCTCGGCTGGCTCCAGAGGATGCA GAGGGCAGACCATGCCTCCCTATGTCCCACCGCTGGGACTGCAGAGCTTGGCTGGCATCG CCAAGCGGCTGGGGCCTCTCCAGCAGTGTCAGGAGCTGGGCGCTCGCTGGCCAGCACAGA GTCGAACTGCAGCCCNCAGAATAATCCAGATAGGGGCATCTGGGTGGAGCTGCAGTGTCG TGGGCTCCTCTCAGAGGCCATCCAGGGCTTGCTGGACTCGNCTGTCCAGGGAGGTGGCTG AGTGGATGGAGACGCCGGGGCACCGATGCTGGTTTCCAGCAGTCAAGCCACAGCTGGTCA GGGNCCTGCTCGTGGCCTNCACTTCTGGCTGCTNCAGCCCTGGGCTTGAGAGTGTGATGC CACAGNCACCACCGCCTGCGGCAGTCAGCTTGCTGTGAAATCCGCGGGCCCTGGTCACCT GGCANAGCTGGTCCATATAGGCGTGTCCCACGCGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000431 |
| Insert Size | 2050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000431.1, NP_000422.1 |
| RefSeq Size | 1952 bp |
| RefSeq ORF | 1191 bp |
| Locus ID | 4598 |
| UniProt ID | Q03426 |
| Domains | GHMP_kinases |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
| Gene Summary | This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201971 | MVK (Myc-DDK-tagged)-Human mevalonate kinase (MVK), transcript variant 1 |
CNY 3,656.00 |
|
| RC201971L1 | Lenti ORF clone of Human mevalonate kinase (MVK), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201971L2 | Lenti ORF clone of Human mevalonate kinase (MVK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201971L3 | Lenti ORF clone of Human mevalonate kinase (MVK), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201971L4 | Lenti ORF clone of Human mevalonate kinase (MVK), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG201971 | MVK (tGFP-tagged) - Human mevalonate kinase (MVK), transcript variant 1 |
CNY 4,370.00 |
