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HTR2C (NM_000868) Human Untagged Clone
CAT＃: SC119615
HTR2C (untagged)-Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C)
CNY 3,656.00
CNY 7,320.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119615 sequence for NM_000868 edited (data generated by NextGen Sequencing)
ATGGTGAACCTGAGGAATGCGGTGCATTCATTCCTTGTGCACCTAATTGGCCTATTGGTT TGGCAATGTGATATTTCTGTGAGCCCAGTAGCAGCTATAGTAACTGACATTTTCAATACC TCCGATGGTGGACGCTTCAAATTCCCAGACGGGGTACAAAACTGGCCAGCACTTTCAATC GTCATCATAATAATCATGACAATAGGTGGCAACATCCTTGTGATCATGGCAGTAAGCATG GAAAAGAAACTGCACAATGCCACCAATTACTTCTTAATGTCCCTAGCCATTGCTGATATG CTAGTGGGACTACTTGTCATGCCCCTGTCTCTCCTGGCAATCCTTTATGATTATGTCTGG CCACTACCTAGATATTTGTGCCCCGTCTGGATTTCTTTAGATGTTTTATTTTCAACAGCG TCCATCATGCACCTCTGCGCTATATCGCTGGATCGGTATGTAGCAGTACGTAATCCTGTT GAGCATAGCCGTTTCAATTCGCGGACTAAGGCCATCATGAAGATTGCTATTGTTTGGGCA ATTTCTATAGGTGTATCAGTTCCTATCCCTGTGATTGGACTGAGGGACGAAGAAAAGGTG TTCGTGAACAACACGACGTGCGTGCTCAACGACCCAAATTTCGTTCTTATTGGGTCCTTC GTAGCTTTCTTCATACCGCTGACGATTATGGTGATTACGTATTGCCTGACCATCTACGTT CTGCGCCGACAAGCTTTGATGTTACTGCACGGCCACACCGAGGAACCGCCTGGACTAAGT CTGGATTTCCTGAAGTGCTGCAAGAGGAATACGGCCGAGGAAGAGAACTCTGCAAACCCT AACCAAGACCAGAACGCACGCCGAAGAAAGAAGAAGGAGAGACGTCCTAGGGGCACCATG CAGGCTATCAACAATGAAAGAAAAGCTTCGAAAGTCCTTGGGATTGTTTTCTTTGTGTTT CTGATCATGTGGTGCCCATTTTTCATTACCAATATTCTGTCTGTTCTTTGTGAGAAGTCC TGTAACCAAAAGCTCATGGAAAAGCTTCTGAATGTGTTTGTTTGGATTGGCTATGTTTGT TCAGGAATCAATCCTCTGGTGTATACTCTGTTCAACAAAATTTACCGAAGGGCATTCTCC AACTATTTGCGTTGCAATTATAAGGTAGAGAAAAAGCCTCCTGTCAGGCAGATTCCAAGA GTTGCCGCCACTGCTTTGTCTGGGAGGGAGCTTAATGTTAACATTTATCGGCATACCAAT GAACCGGTGATCGAGAAAGCCAGTGACAATGAGCCCGGTATAGAGATGCAAGTTGAGAAT TTAGAGTTACCAGTAAATCCCTCCAGTGTGGTTAGCGAAAGGATTAGCAGTGTGTGA Clone variation with respect to NM_000868.2 466 a=>g;478 a=>g >OriGene 5' read for NM_000868 unedited
TTTTGGNNTTGTCGAAATTTTGTATACGACTCACTATAGGCGGCCCGCGATTCGGCACGA GGGAAGAAGCCAAACCTAGCCGGGGGGCGCACGGTCACCCAAGGAGGTCGACTCGCCGGC GCTTCCTATCGCGCCGAGCTCCCTCCATTCCTCTCCCTCCGCCGAGGCGCGAGGTTGCGG CGCGCAGCGCAGCGCAGCTCAGCGCACCGACTGCCGCGGGCTCCGCTGGGCGATTGCAGC CGAGTCCGTTTCTCGTCTAGCTGCCGCCGCGGCGACCGCTGCCTGGTCTTCCTCCCGGAC GCTAGTGGGTTATCAGCTAACACCCGCGAGCATCTATAACATAGGCCAACTGACGCCATC CTTCANAAACAACTGTCTGGGAAAAAAAGAATAAAAAGTAGTGTGAGAGCAGAAAACGTG ATTGAAACACGACCAATCTTTCTTCAGTGCCAAAGGGTGGAAAAGAAAGGGATGATATGA TGAACCTAGCCTGTTAATTNTCGTCTTCTCAATTTTAAACTTTGGGTGCTTAAGACTGAA GCAATCATGGTGAACCTGNAGAATGCGGNGCATTCATTCCTTGTGCACCTATTGGCCTAT TGGTTTGGCAATGTGATATTTCTGGGAGCCCAATAGCAGCTATAGGAACTGGCATTTTTC ATACCCTCCGAGGGGGGGACGCTTCCAAATNCCCAGACGGGGGACAAAACTGGGCAGCCC TTTCAATCGGCATCCTAAAATCATGACAAAAGGTGGCACATTCCTGGGATCATGGCGGGA AGCCTGGGAAAGAAACTGGCCATGGCCCCCATTACTTTTTAAGGCCCTAGCCACTGTGAA TGCCTATGGGACAACCTGGGATGCCCCTGGCCTTCTG >OriGene 3' read for NM_000868 unedited
TTGCATTACGACGACCCCGCTATCTACATGCAGCTCTTTTTTTTTTTTTTTCAACACTTA ATAGATTTAATAAATCAATAGGCAAGTCTCATAAAACCTGTAGTGCATAACATACAGGAA TTAGGAATAAACACAACACTTTGCAACCATTCACAAAAAACCCATTTGACAAAGGGAGAA GACTTACGGTAAATTAGTATAAGGCAGTCTGTTGCTCGTGTCTTACACAGATATACATAT ATAATAATACATCAAAATGATTCGTTTGATGGCAAATTCATCACCTTTACAATTATCACA TGGACTTGTTTAAAACATTTATAAAAGTTTGTAAATTTAACATTGAAGGGTAAGATTTAT ATCCAAACGAGTATATTTGTTTCATACCAAACTGCTCCAAACTTACGAGTAGCACACAAC TTGAGGATAATTACCAGGTTGGGCACTATTAAGTACTACTACTTGCTGACACAGGAATCA TTAACAAATGTGCTGTGAGCTATTATCATTTCACTTATTGCTATTACTTTTGGAAATCTG CGATTTATATTTTGTTCATTTGAAAAACATGGGCTATGAGCTTGCCCTGATAGTTCACAT ATCAGAGGTCTCCAGGTCTTGCTAACACTCACACTACTTCACACCTGAATGCATGGCCCT TTTTAAGGAAAGGCCGAACGGATTTCTCTTCCATCCCTTCTTTCTATAACCTTATTTCGC CCTACTTATAATACAAATCCAGGGGATTATTGCACCATCACATGGCCATACTTGCGAGCA ACCATCTTTNAGTGCCCCAACCTAAGGCTTAAAAGCATGGCCGGGCTACCTTTAAGCACA TTCTCATTTCCGGCAAAGAACAAAATGAATCAACTCTCGGCTCTCTTAAACGTATTTGTA ACATCCCCTTCAACAAAACCTAACTGCCCAGGGAGGAGAAAATGGACCTCCTGCTACAAT CTGGCACTGTCCCACAATATGCATACG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000868 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000868.1, NP_000859.1 |
| RefSeq Size | 4775 bp |
| RefSeq ORF | 1377 bp |
| Locus ID | 3358 |
| UniProt ID | P28335 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction |
| Gene Summary | This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). This variant may undergo RNA editing. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217340 | HTR2C (Myc-DDK-tagged)-Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C) |
CNY 3,656.00 |
|
| RC217340L1 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217340L2 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), mGFP tagged |
CNY 5,890.00 |
|
| RC217340L3 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217340L4 | Lenti ORF clone of Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C), mGFP tagged |
CNY 5,890.00 |
|
| RG217340 | HTR2C (tGFP-tagged) - Human 5-hydroxytryptamine (serotonin) receptor 2C (HTR2C) |
CNY 4,370.00 |
