Plasma Kallikrein 1B (KLKB1) (NM_000892) Human Untagged Clone
CAT#: SC119592
KLKB1 (untagged)-Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1)
CNY 4,760.00
CNY 7,220.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | KLK3; PKK; PKKD; PPK |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_000892, the custom clone sequence may differ by one or more nucleotides
ATGATTTTATTCAAGCAAGCAACTTATTTCATTTCCTTGTTTGCTACAGTTTCCTGTGGATGTCTGACTC AACTCTATGAAAACGCCTTCTTCAGAGGTGGGGATGTAGCTTCCATGTACACCCCAAATGCCCAATACTG CCAGATGAGGTGCACATTCCACCCAAGGTGTTTGCTATTCAGTTTTCTTCCAGCAAGTTCAATCAATGAC ATGGAGAAAAGGTTTGGTTGCTTCTTGAAAGATAGTGTTACAGGAACCCTGCCAAAAGTACATCGAACAG GTGCAGTTTCTGGACATTCCTTGAAGCAATGTGGTCATCAAATAAGTGCTTGCCATCGAGACATTTATAA AGGAGTTGATATGAGAGGAGTCAATTTTAATGTGTCTAAGGTTAGCAGTGTTGAAGAATGCCAAAAAAGG TGCACCAGTAACATTCGCTGCCAGTTTTTTTCATATGCCACGCAAACATTTCACAAGGCAGAGTACCGGA ACAATTGCCTATTAAAGTACAGTCCCGGAGGAACACCTACCGCTATAAAGGTGCTGAGTAACGTGGAATC TGGATTCTCACTGAAGCCCTGTGCCCTTTCAGAAATTGGTTGCCACATGAACATCTTCCAGCATCTTGCG TTCTCAGATGTGGATGTTGCCAGGGTTCTCACTCCAGATGCTTTTGTGTGTCGGACCATCTGCACCTATC ACCCCAACTGCCTCTTCTTTACATTCTATACAAATGTATGGAAAATCGAGTCACAAAGAAATGTTTGTCT TCTTAAAACATCTGAAAGTGGCACACCAAGTTCCTCTACTCCTCAAGAAAACACCATATCTGGATATAGC CTTTTAACCTGCAAAAGAACTTTACCTGAACCCTGCCATTCTAAAATTTACCCGGGAGTTGACTTTGGAG GAGAAGAATTGAATGTGACTTTTGTTAAAGGAGTGAATGTTTGCCAAGAGACTTGCACAAAGATGATTCG CTGTCAGTTTTTCACTTATTCTTTACTCCCAGAAGACTGTAAGGAAGAGAAGTGTAAGTGTTTCTTAAGA TTATCTATGGATGGTTCTCCAACTAGGATTGCGTATGGGACACAAGGGAGCTCTGGTTACTCTTTGAGAT TGTGTAACACTGGGGACAACTCTGTCTGCACAACAAAAACAAGCACACGCATTGTTGGAGGAACAAACTC TTCTTGGGGAGAGTGGCCCTGGCAGGTGAGCCTGCAGGTGAAGCTGACAGCTCAGAGGCACCTGTGTGGA GGGTCACTCATAGGACACCAGTGGGTCCTCACTGCTGCCCACTGCTTTGATGGGCTTCCCCTGCAGGATG TTTGGCGCATCTATAGTGGCATTTTAAATCTGTCAGACATTACAAAAGATACACCTTTCTCACAAATAAA AGAGATTATTATTCACCAAAACTATAAAGTCTCAGAAGGGAATCATGATATCGCCTTGATAAAACTCCAG GCTCCTTTGAATTACACTGAATTCCAAAAACCAATATGCCTACCTTCCAAAGGTGACACAAGCACAATTT ATACCAACTGTTGGGTAACCGGATGGGGCTTCTCGAAGGAGAAAGGTGAAATCCAAAATATTCTACAAAA GGTAAATATTCCTTTGGTAACAAATGAAGAATGCCAGAAAAGATATCAAGATTATAAAATAACCCAACGG ATGGTCTGTGCTGGCTATAAAGAAGGGGGAAAAGATGCTTGTAAGGGAGATTCAGGTGGTCCCTTAGTTT GCAAACACAATGGAATGTGGCGTTTGGTGGGCATCACCAGCTGGGGTGAAGGCTGTGCCCGCAGGGAGCA ACCTGGTGTCTACACCAAAGTCGCTGAGTACATGGACTGGATTTTAGAGAAAACACAGAGCAGTGATGGA AAAGCTCAGATGCAGTCACCAGCATGA >OriGene 5' read for NM_000892 unedited
GTTCACATTTGTATACGACTCCTATAGGGCGGCCGCGAATCGGCACCAGGTTCATTTTTA AGTGACAAGAGACTCACCTCCAAAAAGCAATTGTGTTTTCAGAATGATTTTATTCAAGCA AGCAACTTATTTCATTTCCTTGTTTGCTACAGTTTCCTGTGGATGTCTGACTCAACTCTA TGAAAACGCCTTCTTCAGAGGTGGGGATGTAGCTTCCATGTACACCCCAAATGCCCAATA CTGCCAGATGAGGTGCACATTCCACCCAAGGTGTTTGCTATTCAGTTTTCTTCCAGCAAG TTCAATCAATGACATGGAGAAAAGGTTTGGTTGCTTCTTGAAAGATAGTGTTACAGGAAC CCTGCCAAAAGTACATCGAACAGGTGCAGTTTCTGGACATTCCTTGAAGCAATGTGGTCA TCAAATAAGTGCTTGCCATCGAGACATTTATAAAGGAGTTGATATGAGAGGAGTCAATTT TAATGTGTCTAAGGTTAGCAGTGTTGAAGAATGCCAAAAAAGGTGCACCAGTAACATTCG CTGCCAGTTTTTTTCATATGCCACGCAAACATTTCACAAGGCAGAGTACCGGAACAATTG CCTATTAAAGTACAGTCCCGGAGGAACACCTACCGCTATAAAGGTGCTGAGTAACGTGGA ATCTGGATTCTCACTGAAGCCCTGTGCCCTTTCAGAAATTGGTTGCCACATGAACATCTT CCAGCATCTTGCGTTCTCAGATGTGGATGTTGCCAGGGTTCTCACTCCAGATGCTNNTTG TGTGTCGGACCATCTGCACCTATCACCCCAACTGCCTCTTCTTTACATTCTATACAAATG TATGGAAAATCGAGTCACCAGAAATGTTTGGTCTCTTTAAAACATCTGAAGTGGCACACC AAGTTCCTCTACTCCTCAAGAAACACATATCTGA >OriGene 3' read for NM_000892 unedited
AGTTTGNACGCGGCCGCAATTTANGATCGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAACTTTCACCCTTTTTTTTCACAACACC CAGTCTTGGGAAATTCAATTGGGACCCCCCATTTTCAACCCCTGGTTACGGGGGGCTTAA AAGGGGTTTTAACCAAAAATTGGCCCCAAAAACTTTGAAGGCCCCGGGGTTTTCCCCCTT TGGGGGCAAAAAAAAAGCCCCTTTCCATGCTTTGGAAAAAAAGACCCCCCCGGCTCAAAA TTTGACTTGAACCCAGGGGGGAAAAAATGCCTAAAATTTGGACGGGTTTTCATGGGGGGG AAGGGATTTGAACTTTTCCATCACTGGTTTGGGGTTTCTTTAAAAACCAACCCCTGTTCC CAACGACTTTGGGGGAAAAACCAAGTTGGTTCCTGGGGGGACAACCTTTACCCCAGTTGG GGAGGCCCACCAAACCCCACATTTCATTGGGTTTGGAAACCAAGGGACCCCCTGAATTTC CCTTAAAACATTTTTTCCCCCTTTTTTATAACCAACACAAACCAACCCGGGGGGTATTTT ATAAACTTGGGAATCTTTTCTGGAATTTTTATTTGTTACCAAAGGAATATTTACCCTTTG GAGAATATTTTGGAATCAACCTTTTTCCTTTGGAAAACCCCTTCGGGTACCCCAAAGTGG AAATAAAATGGGCTGGGGCACCTCTTGGAAAGGAGCTAATTGGGTTTTTGGATTCAAGGT AATTAAAGGGAGCTGGGAATTTATTAAGGGGAAATCAGGAATCCCCTCTGAAAATTTATA AGTTTGGGGAAAAAAAATCTTTATTTTGGAAAAAGGGTGTTTTTTGTATGTTCGGAGATT AAAGGCCCCTTATAAGGCCAAACATCTGCGGGGAAGCCTCAAACATGGGCAAATGAGACC CCTG |
Restriction Sites | NotI-NotI |
ACCN | NM_000892 |
Insert Size | 2390 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_000892.2, NP_000883.1 |
RefSeq Size | 2245 bp |
RefSeq ORF | 1917 bp |
Locus ID | 3818 |
UniProt ID | P03952 |
Domains | APPLE, Tryp_SPc, PAN |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Complement and coagulation cascades |
Gene Summary | This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC211985 | KLKB1 (Myc-DDK-tagged)-Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1) |
CNY 4,752.00 |
|
RC211985L3 | Lenti ORF clone of Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC211985L4 | Lenti ORF clone of Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1), mGFP tagged |
CNY 5,890.00 |
|
RG211985 | KLKB1 (tGFP-tagged) - Human kallikrein B, plasma (Fletcher factor) 1 (KLKB1) |
CNY 6,352.00 |
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