United States
Germany
Japan
United Kingdom
China
Factor D (CFD) (NM_001928) Human Untagged Clone
CAT＃: SC118950
CFD (untagged)-Human complement factor D (adipsin) (CFD)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADIPSIN; ADN; DF; PFD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118950 sequence for NM_001928 edited (data generated by NextGen Sequencing)
ATGCACAGCTGGGAGCGCCTGGCAGTTCTGGTCCTCCTAGGAGCGGCCGCCTGCGCGGCG CCGCCCCGTGGTCGGATCCTGGGCGGCAGAGAGGCCGAGGCGCACGCGCGGCCCTACATG GCGTCGGTGCAGCTGAACGGCGCGCACCTGTGCGGCGGCGTCCTGGTGGCGGAGCAGTGG GTGCTGAGCGCGGCGCACTGCCTGGAGGACGCGGCCGACGGGAAGGTGCAGGTTCTCCTG GGCGCGCACTCCCTGTCGCAGCCGGAGCCCTCCAAGCGCCTGTACGACGTGCTCCGCGCA GTGCCCCACCCGGACAGCCAGCCCGACACCATCGACCACGACCTCCTGCTGCTACAGCTG TCGGAGAAGGCCACACTGGGCCCTGCTGTGCGCCCCCTGCCCTGGCAGCGCGTGGACCGC GACGTGGCACCGGGAACTCTCTGCGACGTGGCCGGCTGGGGCATAGTCAACCACGCGGGC CGCCGCCCGGACAGCCTGCAGCACGTGCTCTTGCCAGTGCTGGACCGCGCCACCTGCAAC CGGCGCACGCACCACGACGGCGCCATCACCGAGCGCTTGATGTGCGCGGAGAGCAATCGC CGGGACAGCTGCAAGGGTGACTCCGGGGGCCCGCTGGTGTGCGGGGGCGTGCTCGAGGGC GTGGTCACCTCGGGCTCGCGCGTTTGCGGCAACCGCAAGAAGCCCGGGATCTACACCCGC GTGGCGAGCTATGCGGCCTGGATCGACAGCGTCCTGGCCTAG Clone variation with respect to NM_001928.2 >OriGene 5' read for NM_001928 unedited
NTTGTTCGAATATTTGTATACGACTCACTTATAGGGCGGCCGCGATTCGGCACCAGCTTC ACCATGCACAGCTGGGAGCGCCTGGCAGTTCTGGTCCTCCTAGGAGCGGCCGCCTGCGCG GCGCCGCCCCGTGGTCGGATCCTGGGCGGCAGAGAGGCCGAGGCGCACGCGCGGCCCTAC ATGGCGTCGGTGCAGCTGAACGGCGCGCACCTGTGCGGCGGCGTCCTGGTGGCGGAGCAG TGGGTGCTGAGCGCGGCGCACTGCCTGGAGGACGCGGCCGACGGGAAGGTGCAGGTTCTC CTGGGCGCGCACTCCCTGTCGCAGCCGGAGCCCTCCAAGCGCCTGTACGACGTGCTCCGC GCAGTGCCCCACCCGGACAGCCAGCCCGACACCATCGACCACGACCTCCTGCTGCTACAG CTGTCGGAGAAGGCCACACTGGGCCCTGCTGTGCGCCCCCTGCCCTGGCAGCGCGTGGAC CGCGACGTGGCACCGGGAACTCTCTGCGACGTGGCCGGCTGGGGCATAGTCAACCACGCG GGCCGCCGCCCGGACAGCCTGCAGCACGTGCTCTTGCCAGTGCTGGACCGCGCCACCTGC AACCGGCGCACGCACCACGACGGCGCCATCACCGAGCGCTTGATGTGCGCGGAGAGCAAT CGCCGTGACAGCTGCAAGGGTGACTCCGGNGGCCCGCTGGTGTGCGGNGGCGTGCTCGAG GGCGTGGTCCCCTCGGCTCGCGCGTTTGCGGCAACCGCAAGAAGCCCGGGATCTACACCC GCGTGGCGAGCTATGCGGCCTGGATCGACAGCGTTCTGGCCTAGGGTGCCGGGGCCTGAA GGTCAGGGTCACCCAAGCAACAAAGTCCCGAGCAATGAAGTCATCCACTCCTGCATCTGG TTGGGCTTTTATGAGCACCTACTTATGCAGAGGNGGAGG >OriGene 3' read for NM_001928 unedited
NACCCCAAAAAAACAAACACAAACCACCCCCAAAACCCTTACTTGAACGGGCCGCTTTCT ANATCGAGANTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGCCCAGCTAATTTTTTAT TTATTTGTAAAGATGGAGTCGCGCTACGTGGCCCATGCTGATCTCGAACTCCTGAGATCC AATGATCCTCCCACCTTGGGCTCCCCTTCTGCATATAGTAGGGGCTTAATAAAGACCAAC CAGATGCCGGAGCGGACGACTTCATTGCTCGGGACTTTGTTGCTTGGGTGACCCTGACCT TCAAGCCCCGGCACCCTAGGCCAGGACCCTGTCGATCCAGGCCGGATAGTTTGTCCCGCG GGTGTACATCCCCGGCTTCTTGGGGTTGGCGTACACGCGCGAGCCCGAGGTGACCACACC CTCAATCACGCCCCCGCAAACCCCCCGGCCCCCCTGGCATCACCCTTCCACCCTGTCCGC CCACTGGTTTTCGCGCACATCACAGCCTCCTCGATGTGCCCCCCCTTTCGTGCCCACCCC CTCACGCCCGAGGCGCCCCACCCCCACTCGCCATTAACCCTATCCCAACCCATCCCCGTG TGTCACCCCACGCCGCCCACAATTCCTATTCCCCCCATTACCCTAGACTTATTCCCCCAA GCCCACCTCATCTCCCCACCTAACCCTTGCCCCCTCCCCTCCCTCTTCCCCCCCTCCCCC CTTTCCCCCTCTCACCCCTTTTGCCCCGGCCTCCCTTCCCTTCCTTCCCATTTTCCCTTT TGTCTCTTCTCTACTCCTCTCACTGCCTCCTCTGCCCTCTCGTTCCCCCTCTTCTTCTCC TCCCCCCCCTCCTCCTTCCCTTCCCTCATCCCATTGCTTCCCCCCTTATTCTCCTATCCC TTTCTCACCCTCCCCTCCCCCCTTTTTTN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001928 |
| Insert Size | 1020 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001928.2, NP_001919.2 |
| RefSeq Size | 1173 bp |
| RefSeq ORF | 762 bp |
| Locus ID | 1675 |
| UniProt ID | P00746 |
| Domains | Tryp_SPc |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
| Gene Summary | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209272 | CFD (Myc-DDK-tagged)-Human complement factor D (adipsin) (CFD) |
CNY 2,400.00 |
|
| RC209272L3 | Lenti ORF clone of Human complement factor D (adipsin) (CFD), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209272L4 | Lenti ORF clone of Human complement factor D (adipsin) (CFD), mGFP tagged |
CNY 5,890.00 |
|
| RG209272 | CFD (tGFP-tagged) - Human complement factor D (adipsin) (CFD) |
CNY 4,370.00 |
其它Factor D产品
