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Moesin (MSN) (NM_002444) Human Untagged Clone
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEL70; IMD50 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002444 edited
ATGCCCAAAACGATCAGTGTGCGTGTGACCACCATGGATGCAGAGCTGGAGTTTGCCATC CAGCCCAACACCACCGGGAAGCAGCTATTTGACCAGGTGGTGAAAACTATTGGCTTGAGG GAAGTTTGGTTCTTTGGTCTGCAGTACCAGGACACTAAAGGTTTCTCCACCTGGCTGAAA CTCAATAAGAAGGTGACTGCCCAGGATGTGCGGAAGGAAAGCCCCCTGCTCTTTAAGTTC CGTGCCAAGTTCTACCCTGAGGATGTGTCCGAGGAATTGATTCAGGACATCACTCAGCGC CTGTTCTTTCTGCAAGTGAAAGAGGGCATTCTCAATGATGATATTTACTGCCCGCCTGAG ACCGCTGTGCTGCTGGCCTCGTATGCTGTCCAGTCTAAGTATGGCGACTTCAATAAGGAA GTGCATAAGTCTGGCTACCTGGCCGGAGACAAGTTGCTCCCGCAGAGAGTCCTGGAACAG CACAAACTCAACAAGGACCAGTGGGAGGAGCGGATCCAGGTGTGGCATGAGGAACACCGT GGCATGCTCAGGGAGGATGCTGTCCTGGAATATCTGAAGATTGCTCAAGATCTGGAGATG TATGGTGTGAACTACTTCAGCATCAAGAACAAGAAAGGCTCAGAGCTGTGGCTGGGGGTG GATGCCCTGGGTCTCAACATCTATGAGCAGAATGACAGACTAACTCCCAAGATAGGCTTC CCCTGGAGTGAAATCAGGAACATCTCTTTCAATGATAAGAAATTTGTCATCAAGCCCATT GACAAAAAAGCCCCGGACTTCGTCTTCTATGCTCCCCGGCTGCGGATTAACAAGCGGATC TTGGCCTTGTGCATGGGGAACCATGAACTATACATGCGCCGTCGCAAGCCTGATACCATT GAGGTGCAGCAGATGAAGGCACAGGCCCGGGAGGAGAAGCACCAGAAGCAGATGGAGCGT GCTATGCTGGAAAATGAGAAGAAGAAGCGTGAAATGGCAGAGAAGGAGAAAGAGAAGATT GAACGGGAGAAGGAGGAGCTGATGGAGAGGCTGAAGCAGATCGAGGAACAGACTAAGAAG GCTCAGCAAGAACTGGAAGAACAGACCCGTAGGGCTCTGGAACTTGAGCAGGAACGGAAG CGTGCCCAGAGCGAGGCTGAAAAGCTGGCCAAGGAGCGTCAAGAAGCTGAAGAGGCCAAG GAGGCCTTGCTGCAGGCCTCCCGGGACCAGAAAAAGACTCAGGAACAGCTGGCCTTGGAA ATGGCAGAGCTGACAGCTCGAATCTCCCAGCTGGAGATGGCCCGACAGAAGAAGGAGAGT GAGGCTGTGGAGTGGCAGCAGAAGGCCCAGATGGTACAGGAAGACTTGGAGAAGACCCGT GCTGAGCTGAAGACTGCCATGAGTACACCTCATGTGGCAGAGCCTGCTGAGAATGAGCAG GATGAGCAGGATGAGAATGGGGCAGAGGCTAGTGCTGACCTACGGGCTGATGCTATGGCC AAGGACCGCAGTGAGGAGGAACGTACCACTGAGGCAGAGAAGAATGAGCGTGTGCAGAAG CACCTGAAGGCCCTCACTTCGGAGCTGGCCAATGCCAGAGATGAGTCCAAGAAGACTGCC AATGACATGATCCATGCTGAGAACATGCGACTGGGCCGAGACAAATACAAGACCCTGCGC CAGATCCGGCAGGGCAACACCAAGCAGCGCATTGACGAATTTGAGTCTATGTAA >OriGene 5' read for NM_002444 unedited
NGGACGGTGCANGATTTGTATACGACTCACTATAGGCGGCCGCGAAATCGGCACGAGGGG CCGAATCCAAGCCGTGTGTACTGCGTGCTCAGCACTGCCCGACAGTCCTAGCTAAACTTC GCCAACTCCGCTGCCTTTGCCGCCACCATGCCCAAAACGATCAGTGTGCGTGTGACCACC ATGGATGCAGAGCTGGAGTTTGCCATCCAGCCCAACACCACCGGGAAGCAGCTATTTGAC CAGGTGGTGAAAACTATTGGCTTGAGGGAAGTTTGGTTCTTTGGTCTGCAGTACCAGGAC ACTAAAGGTTTCTCCACCTGGCTGAAACTCAATAAGAAGGTGACTGCCCAGGATGTGCGG AAGGAAAGCCCCCTGCTCTTTAAGTTCCGTGCCAAGTTCTACCCTGAGGATGTGTCCGAG GAATTGATTCAGGACATCACTCAGCGCCTGTTCTTTCTGCAAGTGAAAGAGGGCATTCTC AATGATGATATTTACTGCCCGCCTGAGACCGCTGTGCTGCTGGCCTCGTATGCTGTCCAG TCTAAGTATGGCGACTTCAATAAGGAAGTGCATAAGTCTGGCTACCTGGCCGGAGACAAG TTGCTCCCGCAGAGAGTCCTGGAACAGCACAAACTCAACAAGGACCAGTGGGAGGAGCGG ATCCAGGTGTGGCATGAGGAACACCGTGGCATGCTCAGGGAGGATGCTGTCCTGNAATAT CTGAAGATTGCTCAAGATCTGGAGATGTATGGTGTGAACTACTTCAGCATCAAGAACAAG AAGGCTCANAGCTGTGGCTGGGGGGTGGATGCCCCTGGTCTCACATCTATGAGCAGAATG ACAGACTAACTNCCAGATAGGCTTCCNCTGNAGTGAAATCANGAACATCTCTTTTCATGA TNAGAAATTTGTCATC >OriGene 3' read for NM_002444 unedited
CGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTGAAGTCTTCCTA AATTTTATTGGCACTGAAATAGAACATGGATTGAGCATAAACCCCTCCAAAAACAATTTT TAAAAAACCCAAAAAGTACACAAAAAACCCCTGAATACAAAATCTAACCTTTTCCCCCAG CCTCCCTAAGGGTAAGTTACTGACTTTAAGGCAGCTATTAATAGATTGCCCCACAATTCC AGGTTTCAATTTAGCCAATATAGGACATATCACCAAGTGAGCTAATTCACAGCAATGCAC ACAAGACTCCTCAAGGTCAGGCACAGAGTGGGGGGTGGTGGCCAGGGGGAATTGAGGGAG GCTCTAAGCTAGGGGCACTGCATGGTGGGACAGGATGGCCCCTTGAGGACTGAACCCTGG GGAGAAGACAAACCGTTATAATAAAAACAAATAACAAGTACTTTAAGAATGGATTGTTTG ACCTATAGTGACAGATGACATCACTAATACTGAAAGCTTCTTATTTAATAATTTTGGCAA AACGTAATTTTGAAAAAAGAAAATGCTTTCCAGGTGTGGGGGCGGAAAAGAATGAGGCCA AAAAATTCCTGCCCCAAAACTAATATCTTTCTATGGTGCCTTACCCAGGAAAGCTTAAAC CAATTCTTAAATTCCACATAGGCCCTAACCCTGCGGAAGAAGAACAGCCCCTCGACACCA AAAAGCGGCGGATGCTTCTGTGTTGAAAACAGGGGCGGGGTGTTGAACGGTCTTGTCCTA ATTCGCCTGCTCTTTGGTATAACATTCAAAGGTAATTAATCTGGTTTTATAACTTGTCAC AAGTTCTTTATACACGGTNGTACATCATTCTATTTAGCGTACCATTACAAGTGATCTTTC TTTCTCTACGGCGCCTATATCTTCCTTCCGTAACATCCAACATATCCTGCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002444 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002444.2, NP_002435.1 |
| RefSeq Size | 3981 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 4478 |
| UniProt ID | P26038 |
| Domains | B41, ERM |
| Protein Families | Druggable Genome |
| Protein Pathways | Leukocyte transendothelial migration, Regulation of actin cytoskeleton |
| Gene Summary | Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
G protein-coupled receptor kinase GRK5 phosphorylates moesin and regulates metastasis in prostate cancer
,Chakraborty, PK;Zhang, Y;Coomes, AS;Kim, WJ;Stupay, R;Lynch, LD;Atkinson, T;Kim, JI;Nie, Z;Daaka, Y;,
Cancer Res. April 2014
,PubMed ID 24755472
[MSN]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205674 | MSN (Myc-DDK-tagged)-Human moesin (MSN) |
CNY 4,296.00 |
|
| RC205674L1 | Lenti ORF clone of Human moesin (MSN), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC205674L2 | Lenti ORF clone of Human moesin (MSN), mGFP tagged |
CNY 6,460.00 |
|
| RC205674L3 | Lenti ORF clone of Human moesin (MSN), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC205674L4 | Lenti ORF clone of Human moesin (MSN), mGFP tagged |
CNY 6,460.00 |
|
| RG205674 | MSN (tGFP-tagged) - Human moesin (MSN) |
CNY 5,040.00 |
