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Thymidine Kinase 1 (TK1) (NM_003258) Human Untagged Clone
CAT＃: SC118084
TK1 (untagged)-Human thymidine kinase 1, soluble (TK1)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TK2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118084 sequence for NM_003258 edited (data generated by NextGen Sequencing)
ATGAGCTGCATTAACCTGCCCACTGTGCTGCCCGGCTCCCCCAGCAAGACCCGGGGGCAG ATCCAGGTGATTCTCGGGCCGATGTTCTCAGGAAAAAGCACAGAGTTGATGAGACGCGTC CGTCGCTTCCAGATTGCTCAGTACAAGTGCCTGGTGATCAAGTATGCCAAAGACACTCGC TACAGCAGCAGCTTCTGCACACATGACCGGAACACCATGGAGGCGCTGCCCGCCTGCCTG CTCCGAGACGTGGCCCAGGAGGCCCTGGGCGTGGCTGTCATAGGCATCGACGAGGGGCAG TTTTTCCCTGACATCGTGGAGTTCTGCGAGGCCATGGCCAACGCCGGGAAGACCGTAATT GTGGCTGCACTGGATGGGACCTTCCAGAGGAAGCCATTTGGGGCCATCCTGAACCTGGTG CCGCTGGCCGAGAGCGTGGTGAAGCTGACGGCGGTGTGCATGGAGTGCTTCCGGGAAGCC GCCTATACCAAGAGGCTCGGCACAGAGAAGGAGGTCGAGGTGATTGGGGGAGCAGACAAG TACCACTCCGTGTGTCGGCTCTGCTACTTCAAGAAGGCCTCAGGCCAGCCTGCCGGGCCG GACAACAAAGAGAACTGCCCAGTGCCAGGAAAGCCAGGGGAAGCCGTGGCTGCCAGGAAG CTCTTTGCCCCACAGCAGATTCTGCAATGCAGCCCTGCCAACTGA Clone variation with respect to NM_003258.4 33 t=>c;225 a=>g >OriGene 5' read for NM_003258 unedited
CACACCACGGCCCACNACCCCCTTCCACCCGCCTTGTTCACATTTGTATACGACTCACTA TAGGCGGCCGCGNATATCGCACGAGCGGGAGCGCAATGAGCTGCATTAACCTGCCCATGT GCTGCCCGGCTCCCCCAGCAAGACCCGGGGGCAGATCCAGGTGATTCTCGGGCCGATGTT CTCAGGAAAAAGCACAGAGTTGATGAGACGCGTCCGTCGCTTCCAGATTGCTCAGTACAA GTGCCTGGTGATCAAGTATGCCAAAGACACTCGCTACAGCAGCAGCTTCTGCACACATGA CCGGAACACCATGGAGGCGCTGCCCGCCTGCCTGCTCCGAGACGTGGCCCAGGAGGCCCT GGGCGTGGCTGTCATAGGCATCGACGAGGGGCAGTTTTTCCCTGACATCGTGGAGTTCTG CGAGGCCATGGCCAACGCCGGGAAGACCGTAATTGTGGCTGCACTGGATGGGACCTTCCA GAGGAAGCCATTTGGGGCCATCCTGAACCTGGTGCCGCTGGCCGAGAGCGTGGTGAAGCT GACGGCGGTGTGCATGGAGTGCTTCCGGGAAGCCGCCTATACCAAGAGGCTCGGCACAGA GAAGGAGGTCGAGGTGATTGNGGGAGCAGACAAGTACCACTCCGTGTGTCGGCTCTGCTA CTTCAAGAAAGCCTCAGGCCAGCCTGCCGGGCCGGACAACANAGAAACTGCCCAGTGCCA GGAAAGCCAGGGGAAGCCGTGGCTGCCAGAAAGCTCTTTGCCCCACAGCAGATTCTGCAA TGCAGCCCTGTCCACTGAGGGACCTGCGATGGCCGNCCGCTCCCTTCCTGCCACTGGCGN CTACTGGACCCTGCCCTGCATGCTTGCCAGCCACTCCCAGAAGAAGTCGGGAAGG >OriGene 3' read for NM_003258 unedited
GGGTTGCTATGGAACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCCCCCCCCCC GGGAATTTTCAATTATTTAATTTCAAAACCTACAGCAAAGGGGGGGCCCCGGCCCTTCCC CCCTTAAAAAAAAACCCCCGGGGATCCAATTCCCAAAAGGGTGGGGCCCCCCCATTTTGG GAAAAAATGCTTTTTTTCCTGGGGAAACCCTCCCCAAAGGTGGGAAGGGTTTTGACCCCA AAAGGAAACAAAAGGGGGGGAACCCCGCCCCCCCCCGGGGGGGGGGGGGACCCCCTCCCA GGCAAAAGGGCCTAACCCTCATGGGGGGCCAAGGCTAAAAGGGGCTGGCCCAGGCTTCCC AGGGAAAAAAAAAACCCCCCTTTGAAACCCCCAAAGGGGAAAAACCAGGCTGATTTCAAC AGGGGGGGGCTTTTCCCCCCACCCCAAGGAGAGGGAGGGGGCCAAATCCCAGGCCACCAA GGGGGGCCGGTTCCACCCGGGGCAATCTTCCCCCCCCCTGAAAGGGAACCTTTAAACAAA CCATTGGGTAAAAAAAAAAGGAACTTGCCCCGGGGGGGGCCCCCCCACAAGAGAAATTCT CCAAAGGCCAAGGTGTGGGTATCTTCCCGCCTCCCAATTTTTTTTGGAAGGGCTGGGCAC ATGCAGGGGAACCTCCCATTAGCCGCAATTGCAAAAAGAGACGGGGCCCCCCTCGAAGGT CCCTTATTTGGGAGGGCTCCTTTTAAAAAATTGGGTGGGGGAAAAAAATTTCTGGGGGCC CCGGGTTTCCCTGGTTTTTTGGGCGGGGGGAAGTTTTTTTTTTTTTCCGCCCCGAAGGTG GGCTTAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003258 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003258.1, NP_003249.1 |
| RefSeq Size | 1421 bp |
| RefSeq ORF | 705 bp |
| Locus ID | 7083 |
| UniProt ID | P04183 |
| Domains | TK |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism |
| Gene Summary | The protein encoded by this gene is a cytosolic enzyme that catalyzes the addition of a gamma-phosphate group to thymidine. This creates dTMP and is the first step in the biosynthesis of dTTP, which is one component required for DNA replication. The encoded protein, whose levels fluctuate depending on the cell cycle stage, can act as a low activity dimer or a high activity tetramer. High levels of this protein have been used as a biomarker for diagnosing and categorizing many types of cancers. [provided by RefSeq, Oct 2016] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218280 | TK1 (Myc-DDK-tagged)-Human thymidine kinase 1, soluble (TK1) |
CNY 2,400.00 |
|
| RC218280L1 | Lenti ORF clone of Human thymidine kinase 1, soluble (TK1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC218280L2 | Lenti ORF clone of Human thymidine kinase 1, soluble (TK1), mGFP tagged |
CNY 5,890.00 |
|
| RC218280L3 | Lenti ORF clone of Human thymidine kinase 1, soluble (TK1), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC218280L4 | Lenti ORF clone of Human thymidine kinase 1, soluble (TK1), mGFP tagged |
CNY 5,890.00 |
|
| RG218280 | TK1 (tGFP-tagged) - Human thymidine kinase 1, soluble (TK1) |
CNY 4,000.00 |
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