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Zyxin (ZYX) (NM_003461) Human Untagged Clone
CAT＃: SC117947
ZYX (untagged)-Human zyxin (ZYX), transcript variant 1
CNY 4,264.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ESP-2; HED-2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117947 sequence for NM_003461 edited (data generated by NextGen Sequencing)
ATGGCGGCCCCCCGCCCGTCTCCCGCGATCTCCGTTTCGGTCTCGGCTCCGGCTTTTTAC GCCCCGCAGAAGAAGTTCGGCCCTGTGGTGGCCCCAAAGCCCAAAGTGAATCCCTTCCGG CCCGGGGACAGCGAGCCTCCCCCGGCACCCGGGGCCCAGCGCGCACAGATGGGCCGGGTG GGCGAGATTCCCCCGCCGCCCCCGGAAGACTTTCCCCTGCCTCCACCTCCCCTTGCTGGG GATGGCGACGATGCAGAGGGTGCTCTGGGAGGTGCCTTCCCGCCGCCCCCTCCCCCGATC GAGGAATCATTTCCCCCTGCGCCTCTGGAGGAGGAGATCTTCCCTTCCCCGCCGCCTCCT CCGGAGGAGGAGGGAGGGCCTGAGGCCCCCATACCGCCCCCACCACAGCCCAGGGAGAAG GTGAGCAGTATTGATTTGGAGATCGACTCTCTGTCCTCACTGCTGGATGACATGACCAAG AATGATCCTTTCAAAGCCCGGGTGTCATCTGGATATGTGCCCCCACCAGTGGCCACTCCA TTCAGTTCCAAGTCCAGTACCAAGCCTGCAGCCGGGGGCACAGCACCCCTGCCTCCTTGG AAGTCCCCTTCCAGCTCCCAGCCTCTGCCCCAGGTTCCGGCTCCGGCTCAGAGCCAGACA CAGTTCCATGTTCAGCCCCAGCCCCAGCCCAAGCCTCAGGTCCAACTCCATGTCCAGTCC CAGACCCAGCCTGTGTCTTTGGCTAACACCCAGCCCCGAGGGCCCCCAGCCTCATCTCCG GCTCCAGCCCCTAAGTTTTCTCCAGTGACTCCTAAGTTTACTCCTGTGGCTTCCAAGTTC AGTCCTGGAGCCCCAGGTGGATCTGGGTCACAACCAAATCAAAAATTGGGGCACCCCGAA GCTCTTTCTGCTGGCACAGGCTCCCCTCAACCTCCCAGCTTCACCTATGCCCAGCAGAGG GAGAAGCCCCGAGTGCAGGAGAAGCAGCACCCCGTGCCCCCACCGGCTCAGAACCAAAAC CAGGTGCGCTCCCCTGGGGCCCCAGGGCCCCTGACTCTGAAGGAGGTGGAGGAGCTGGAG CAGCTGACCCAGCAGCTAATGCAGGACATGGAGCATCCTCAGAGGCAGAATGTGGCTGTC AACGAACTCTGCGGCCGATGCCATCAACCCCTGGCCCGGGCGCAGCCAGCCGTCCGCGCT CTAGGGCAGCTGTTCCACATCGCCTGCTTCACCTGCCACCAGTGTGCGCAGCAGCTCCAG GGCCAGCAGTTCTACAGTCTGGAGGGGGCGCCGTACTGCGAGGGCTGTTACACTGACACC CTGGAGAAGTGTAACACCTGCGGGGAGCCCATCACTGACCGCATGCTGAGGGCCACGGGC AAGGCCTATCACCCGCACTGCTTCACCTGTGTGGTCTGCGCCCGCCCCCTGGAGGGCACC TCCTTCATCGTGGACCAGGCCAACCGGCCCCACTGTGTCCCCGACTACCACAAGCAGTAC GCCCCGAGGTGCTCCGTCTGCTCTGAGCCCATCATGCCTGAGCCTGGCCGAGATGAGACT GTGCGAGTGGTCGCCCTGGACAAGAACTTCCACATGAAGTGTTACAAGTGTGAGGACTGC GGGAAGCCCCTGTCGATTGAGGCAGATGACAATGGCTGCTTCCCCCTGGACGGTCACGTG CTCTGTCGGAAGTGCCACACTGCTAGAGCCCAGACCTGA Clone variation with respect to NM_003461.4 >OriGene 5' read for NM_003461 unedited
TTTGTAATACGACTCACTATAGGGCGGCCGCGCCGGCGCCGAGGCGGCCACCCGAGACGC GGCGCGCACGCTCCGGCCTGCGCAGCCCGGCCCGGCCATGGCGGCCCCCCGCCCGTCTCC CGCGATCTCCGTTTCGGTCTCGGCTCCGGCTTTTTACGCCCCGCAGAAGAAGTTCGGCCC TGTGGTGGCCCCAAAGCCCAAAGTGAATCCCTTCCGGCCCGGGGACAGCGAGCCTCCCCC GGCACCCGGGGCCCAGCGCGCACAGATGGGCCGGGTGGGCGAGATTCCCCCGCCGCCCCC GGAAGACTTTCCCCTGCCTCCACCTCCCCTTGCTGGGGATGGCGACGATGCAGAGGGTGC TCTGGGAGGTGCCTTCCCGCCGCCCCCTCCCCCGATCGAGGAATCATTTCCCCCTGCGCC TCTGGAGGAGGAGATCTTCCCTTCCCCGCCGCCTCCTCCGGAGGAGGAGGGAGGGCCTGA GGCCCCCATACCGCCCCCACCACAGGTACGGAGGCCTGGGAGGGGCGGCTGCACTGGACA CCCCCAAGGAGAGGAGAAGAGGGCCCTTTCTTCTTACCTCCCCTGCACCTCTGCCTTGGG GGTGGGGGGATAGAGGCATGGAATAGGTGCTCTGACCTCTGACCCTCTAGCCCAGGGAGA AGGTGAGCAGTATTGATTTGGAGATCGACTCTCTGTCCTCACTGCTGGATGACATGACCA AGAATGATCCTTTTCANAGCCCGGNTGTCATTCTGGATATGTGCCCCCACCAGTGGCCAC TTCATTCAGTTTCCAGTTCAGTACCAAGCCTGCAGCCCGGGGCACAGCACCCCTGGCTCC TTGGAAGTCCCCTTNCAGCTCCCAGCTCTGCCCCAGGTTCCGCTCCGNCTTAAACCCAAA ACATTTCTTGTTCAGCCCCACC >OriGene 3' read for NM_003461 unedited
GTACGCGGCCGCAATTTANGATCGAGTTTTTTTTTTTTTTTTTTGGAAAACAAGGTTTTT TTTTATTTGTAGCTATAGCTACAACTTGGCAGCATGGGGGAGGGTGGGAATGTCCTGGAG GGTCTCCCAGCCCTCCGCAAGCAGAGTACAAAGGCTGCTTGGGGGGCCGGCCGAGGGCGC GGGTGCAGCAGTGAAAGCAGCAGCACTAAACCTGGTGCCCCCCTCAGGTGGGGTGTCTGG AAGACGGTGGGCAATCCCTGCAGGATGGGCGAGGACCAGACCCCAGGGCGGGGATCCTGC ATCCCTAGACCATGTTGGGTCCTGGGTCAGGGCACCTGGGATGCTAGGGAGGGGTTGGAA ATGGGAGGGGCTAGACATCAAAACAATAACTGAGGTGGGGGCAGGTGGTCTCAGTGTGGG TGGTCCACAATGGGGCATGGACTGCGGTCTGAAGAGGGCCTGTCCTCACTCAGGTCTGGG CTCTAGCAGTGTGGCACTTCCGACAGAGCACGTGACCGTCCAGGGGGAAGCAGCCATTGT CATCTGCCTCAATCGACAGGGGCTTCCCGCAGTCCTCACACTTGTAACACTTCATGTGGA AGTTCTTGTCCAGGGCGACCACTCGCACAGTCTCATCTCGGCCAGGCTCAGGCATGATGG GCTCAGAGCAGACGGAGCACCTCGGCGCGTACTGCTTGTGGTAGTCGGGGACACAGTGGG GCCCGGTTGGCCTTGTCCACGATGAAAGAAGTGCCCTCAGGGGGCGGGCGCACACACACA GTGAAGCAGTGCCGGTGAAAGGCTTGCCCGGGCCCTTAACATGCGCCAATGATGGCTCCC CCCAGGGTTACACCTCTCCGGGNGATAGGGAACAAGCCCTCGCAGAAGGCCGCCACTCCA AAATGACAACTGGGTCCCTGGGN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003461 |
| Insert Size | 2390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003461.4, NP_003452.1 |
| RefSeq Size | 2325 bp |
| RefSeq ORF | 1719 bp |
| Locus ID | 7791 |
| UniProt ID | Q15942 |
| Domains | LIM |
| Protein Pathways | Focal adhesion |
| Gene Summary | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214079 | ZYX (Myc-DDK-tagged)-Human zyxin (ZYX), transcript variant 1 |
CNY 3,990.00 |
|
| RC214079L1 | Lenti-ORF clone of ZYX (Myc-DDK-tagged)-Human zyxin (ZYX), transcript variant 1 |
CNY 5,890.00 |
|
| RC214079L2 | Lenti-ORF clone of ZYX (mGFP-tagged)-Human zyxin (ZYX), transcript variant 1 |
CNY 5,890.00 |
|
| RC214079L3 | Lenti-ORF clone of ZYX (Myc-DDK-tagged)-Human zyxin (ZYX), transcript variant 1 |
CNY 5,890.00 |
|
| RC214079L4 | Lenti-ORF clone of ZYX (mGFP-tagged)-Human zyxin (ZYX), transcript variant 1 |
CNY 5,890.00 |
|
| RG214079 | ZYX (tGFP-tagged) - Human zyxin (ZYX), transcript variant 1 |
CNY 4,370.00 |
