United States
Germany
Japan
United Kingdom
China
NR2F6 (NM_005234) Human Untagged Clone
CAT＃: SC116862
NR2F6 (untagged)-Human nuclear receptor subfamily 2, group F, member 6 (NR2F6)
CNY 3,656.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EAR-2; EAR2; ERBAL2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005234 edited
GGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTG TAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCCTGGAACCGGCCCGACCA GTTCCGCCCGGGCGCGAGGACCGGCCGCAGGAAGTTGCTGCAAAACTTTTTTGGGGGGTG CAGCCCGTGCCCCCCGCGCGCCGGGGCCGAATGCGCGCCGCGTAGGGTCCCCCGGGCCGA GAGGGGTGCCCGGAGGGAAGAGCGCGGTGGGGGCGCCCCGGCCCCGCTGCCCTGGGGCTA TGGCCATGGTGACCGGCGGCTGGGGCGGCCCCGGCGGCGACACGAACGGCGTGGACAAGG CGGGCGGCTACCCGCGCGCGGCCGAGGACGACTCGGCCTCGCCCCCCGGTGCCGCCAGCG ACGCCGAGCCGGGCGACGAGGAGCGGCCGGGGCTGCAGGTGGACTGCGTGGTGTGCGGGG ACAAGTCGAGCGGCAAGCATTACGGTGTCTTCACCTGCGAGGGCTGCAAGAGCTTTTTCA AGCGAAGCATCCGCCGCAACCTCAGCTACACCTGCCGGTCCAACCGTGACTGCCAGATCG ACCAGCACCACCGGAACCAGTGCCAGTACTGCCGTCTCAAGAAGTGCTTCCGGGTGGGCA TGAGGAAGGAGGCGGTGCAGCGCGGCCGCATCCCGCACTCGCTGCCTGGTGCCGTGGCCG CCTCCTCGGGCAGCCCCCCGGGCTCGGCGCTGGCGGCAGTGGCGAGCGGCGGAGACCTCT TCCCGGGGCAGCCGGTGTCCGAACTGATCGCGCAGCTGCTGCGCGCTGAGCCCTACCCTG CGGCGGCCGGACGCTTCGGCGCAGGGGGCGGCGCGGCGGGCGCGGTGCTGGGCATCGACA ACGTGTGCGAGCTGGCGGCGCGGCTGCTCTTCAGCACCGTGGAGTGGGCGCGCCACGCGC CCTTCTTCCCCGAGCTGCCGGTGGCCGACCAGGTGGCGCTGCTGCGCCTGAGCTGGAGCG AGCTCTTCGTGCTGAACGCGGCGCAGGCGGCGCTGCCCCTGCACACGGCGCCGCTACTGG CCGCCGCCGGCCTCCACGCCGCGCCTATGGCCGCCGAGCGCGCCGTGGCTTTCATGGACC AGGTGCGCGCCTTCCAGGAGCAGGTGGACAAGCTGGGCCGCCTGCAGGTCGACTCGGCCG AGTATGGCTGCCTCAAGGCCATCGCGCTCTTCACGCCCGACGCCTGTGGCCTCTCAGACC CGGCCCACGTTGAGAGCCTGCAGGAGAAGGCGCAGGTGGCCCTCACCGAGTATGTGCGGG CGCAGTACCCGTCCCAGCCCCAGCGCTTCGGGCGCCTGCTGCTGCGGCTCCCCGCCCTGC GCGCGGTCCCTGCCTCCCTCATCTCCCAGCTGTTCTTCATGCGCCTGGTGGGGAAGACGC CCATTGAGACACTGATCAGAGACATGCTGCTGTCGGGGAGTACCTTCAACTGGCCCTACG GCTCGGGCCAGTGACCATGACGGGGCCACGTGTGCTGTGGCCAGGCCTGCAGACAGACCT CAAGGGACAGGGAATGCTGAGGCCTCGAGGGGCCTCCCGGGGCCCAGGACTCTGGCTTCT CTCCTCAGACTTCTATTTTTTAAAGACTGTGAAATGTTTGTCTTTTCTGTTTTTTAAATG ATCATGAAACCAAAAAGAGACTGATCATCCAGGCCTCAGCCTCATCCTCCCCAGGACCCC TGTCCAGGATGGAGGGTCCAATCCTAGGACAGCCTTGTTCCTCAGCACCCCTAGCATGAA CTTGTGGGATGGTGGGGTTGGCTTCCCTGGCATGATGGACAAAGGCCTGGCGTCGGCCAG AGGGGCTGCTCCAGTGGGCAGGGGTAGCTAGCGTGTGCCAGGCAGATCCTCTGGACACGT AACCTATGTCAGACACTACATGATGACTCAAGGCCAA >OriGene 5' read for NM_005234 unedited
TTATATTTGTNAATACGCACTCACTTATAGGGCGGCCGCGAATTCGCACGAGCCTGGAAC CGGCCCGACCAGTTCCGCCCGGGCGCGAGGACCGGCCGCAGGAAGTTGCTGCAAAACTTT TTTGGGGGGTGCAGCCCGTGCCCCCCGCGCGCCGGGGCCGAATGCGCGCCGCGTAGGGTC CCCCGGGCCGAGAGGGGTGCCCGGAGGGAAGAGCGCGGTGGGGGCGCCCCGGCCCCGCTG CCCTGGGGCTATGGCCATGGTGACCGGCGGCTGGGGCGGCCCCGGCGGCGACACGAACGG CGTGGACAAGGCGGGCGGCTACCCGCGCGCGGCCGAGGACGACTCGGCCTCGCCCCCCGG TGCCGCCAGCGACGCCGAGCCGGGCGACGAGGAGCGGCCGGGGCTGCAGGTGGACTGCGT GGTGTGCGGNGACAAGTCGAGCGGCAAGCATTACGGTGTCTTCACCTGCGAGGGCTGCAA GAGCTTTTTCAAGCGAAGCATCCGCCGCAACCTCAGCTACACCTGCCGGTCCAACCGTGA CTGCCAGATCGACCAGCACCACCGGAACCAGTGCCAGTACTGCCGTCTCAAGAAGTGCTT CCGGGTGGGCATGAAGAAAGANGCGGTGCAGCGCGGCCGCATCCCGCACTCGCTGCCTGG TGCCGTGGNCGCCTTCTCGGNCAGCCCCCCGGGCTTCGCGCTTGCGCCATTGCGAGCGGC GGAGACCTCTTCCCGGNGCAGCCCGTGTCCGAACTGATCGCGCAGCTGCTGCGCGCTGAC CCCTACCTGCGGCGGCCGAACCCTTCGCCCAGGNGGCGGCCCGATGGCCCCGTGCTGGCA TCNACACGTGTGCGAGCTGGCGGCGCGCTGCTCTTCACAACGTGATTGGGCGCGCACGCG CCCTTTTTCCCGACTGCCGTGGCCGACAAGTGCGCTGTTCCCTGACTGTACAACTCTTTG CTGACCG >OriGene 3' read for NM_005234 unedited
AAGTGTGGGCAAGTCTTTTTTTGGCCTTGGATCTCATGTAGTGTCTGACATAGGTTACGT GTCCAGAGGATCTGCCTGGCACACGCTAGCTACCCCTGCCCACTGGAGCAGCCCCTCTGG CCGACGCCAGGCCTTTGTCCATCATGCCAGGGAAGCCAACCCCACCATCCCACAAGTTCA TGCTAGGGGTGCTGAGGAACAAGGCTGTCCTAGGATTGGACCCTCCATCCTGGACAGGGG TCCTGGGGAGGATGAGGCTGAGGCCTGGATGATCAGTCTCTTTTTGGTTTCATGATCATT TAAAAAACAGAAAAGACAAACATTTCACAGTCTTTAAAAAATAGAAGTCTGAGGAGAGAA GCCAGAGTCCTGGGCCCCGGGAGGCCCCTCGAGGCCTCAGCATTCCCTGTCCCTTGAGGT CTGTCTGCAGGCCTGGCCACAGCACACGTGGCCCCGTCATGGTCACTGGCCCGAGCCGTA NGGCCAGTTGAAGGTACTCCCCGACAGCAGCATGTCTCTGATCAGTGTCTCAATGGGCGT CTTCCCCACCAGGCGCATGAAGAACAGCTGGGAGATGAGGGAGGCAGGGACCGCGCCGCA GGCGGGGAGCCGCAGCAGCAGGCGCCCGAAGCGCTGGGGCTTGGGACGGGTACTGCGCCC GCACATACTCGGTGAGGGCCACCTGCGCCTTCTCCTGCAGGCTCTCAACGTGGGGCGGGT TCTGAGAGGGCACAGCCCGTTCGCCGCGAAAAACCGCAAGGCCCTTGAAGGCAGCATACT CGGCCCGGTCGACCTGAAGGCGGCCCATTTGTTCCCCTGCTCCGGGAAGCCGCCCCCTGG TCCAGGAAAGCCCGGGCGCTCTGCGGCCTAGCCCCGCGTGGAGCCCGCGGTGGCCATAAC CGGCCCTGGTGCCGGGCCCCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005234 |
| Insert Size | 1980 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005234.3, NP_005225.2 |
| RefSeq Size | 1804 bp |
| RefSeq ORF | 1215 bp |
| Locus ID | 2063 |
| UniProt ID | P10588 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Gene Summary | Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201336 | NR2F6 (Myc-DDK-tagged)-Human nuclear receptor subfamily 2, group F, member 6 (NR2F6) |
CNY 5,488.00 |
|
| RC201336L1 | Lenti ORF clone of Human nuclear receptor subfamily 2, group F, member 6 (NR2F6), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201336L2 | Lenti ORF clone of Human nuclear receptor subfamily 2, group F, member 6 (NR2F6), mGFP tagged |
CNY 7,888.00 |
|
| RC201336L3 | Lenti ORF clone of Human nuclear receptor subfamily 2, group F, member 6 (NR2F6), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201336L4 | Lenti ORF clone of Human nuclear receptor subfamily 2, group F, member 6 (NR2F6), mGFP tagged |
CNY 7,888.00 |
|
| RG201336 | NR2F6 (tGFP-tagged) - Human nuclear receptor subfamily 2, group F, member 6 (NR2F6) |
CNY 7,088.00 |
