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ITK (NM_005546) Human Untagged Clone
CAT＃: SC116679
ITK (untagged)-Human IL2-inducible T-cell kinase (ITK)
CNY 4,624.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EMT; LPFS1; LYK; PSCTK2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005546 edited
ATGAACAACTTTATCCTCCTGGAAGAACAGCTCATCAAGAAATCCCAACAAAAGAGAAGA ACTTCTCCCTCGAACTTTAAAGTCCGCTTCTTTGTGTTAACCAAAGCCAGCCTGGCATAC TTTGAAGATCGTCATGGGAAGAAGCGCACGCTGAAGGGGTCCATTGAGCTCTCCCGAATC AAATGTGTTGAGATTGTGAAAAGTGACATCAGCATCCCATGCCACTATAAATACCCGTTT CAGGTGGTGCATGACAACTACCTCCTATATGTGTTTGCTCCAGATCGTGAGAGCCGGCAG CGCTGGGTGCTGGCCCTTAAAGAAGAAACGAGGAATAATAACAGTTTGGTGCCTAAATAT CATCCTAATTTCTGGATGGATGGGAAGTGGAGGTGCTGTTCTCAGCTGGAGAAGCTTGCA ACAGGCTGTGCCCAATATGATCCAACCAAGAATGCTTCAAAGAAGCCTCTTCCTCCTACT CCTGAAGACAACAGGCGACCACTTTGGGAACCTGAAGAAACTGTGGTCATTGCCTTATAT GACTACCAAACCAATGATCCTCAGGAACTCGCACTGCGGCGCAACGAAGAGTACTGCCTG CTGGACAGTTCTGAGATTCACTGGTGGAGAGTCCAGGACAGGAATGGGCATGAAGGATAT GTACCAAGCAGTTATCTGGTGGAAAAATCTCCAAATAATCTGGAAACCTATGAGTGGTAC AATAAGAGTATCAGCCGAGACAAAGCTGAAAAACTTCTTTTGGACACAGGCAAAGAAGGA GCCTTCATGGTAAGGGATTCCAGGACTGCAGGAACATACACCGTGTCTGTTTTCACCAAG GCTGTTGTAAGTGAGAACAATCCCTGTATAAAGCATTATCACATCAAGGAAACAAATGAC AATCCTAAGCGATACTATGTGGCTGAAAAGTATGTGTTCGATTCCATCCCTCTTCTCATC AACTATCACCAACATAATGGAGGAGGCCTGGTGACTCGACTCCGGTATCCAGTTTGTTTT GGGAGGCAGAAAGCCCCAGTTACAGCAGGGCTGAGATACGGGAAATGGGTGATCGACCCC TCAGAGCTCACTTTTGTGCAAGAGATTGGCAGTGGGCAATTTGGGTTGGTGCATCTGGGC TACTGGCTCAACAAGGACAAGGTGGCTATCAAAACCATTCGGGAAGGGGCTATGTCAGAA GAGGACTTCATAGAGGAGGCTGAAGTAATGATGAAACTCTCTCATCCCAAACTGGTGCAG CTGTATGGGGTGTGCCTGGAGCAGGCCCCCATCTGCCTGGTGTTTGAGTTCATGGAGCAC GGCTGCCTGTCAGATTATCTACGCACCCAGCGGGGACTTTTTGCTGCAGAGACCCTGCTG GGCATGTGTCTGGATGTGTGTGAGGGCATGGCCTACCTGGAAGAGGCATGTGTCATCCAC AGAGACTTGGCTGCCAGAAATTGTTTGGTGGGAGAAAACCAAGTCATCAAGGTGTCTGAC TTTGGGATGACAAGGTTCGTTCTGGATGATCAGTACACCAGTTCCACAGGCACCAAATTC CCGGTGAAGTGGGCATCCCCAGAGGTTTTCTCTTTCAGTCGCTATAGCAGCAAGTCCGAT GTGTGGTCATTTGGTGTGCTGATGTGGGAAGTTTTCAGTGAAGGCAAAATCCCGTATGAA AACCGAAGCAACTCAGAGGTGGTGGAAGACATCAGTACCGGATTTCGGTTGTACAAGCCC CGGCTGGCCTCCACACACGTCTACCAGATTATGAATCACTGCTGGAAAGAGAGACCAGAA GATCGGCCAGCCTTCTCCAGACTGCTGCGTCAACTGGCTGAAATTGCAGAATCAGGACTT TAG >OriGene 5' read for NM_005546 unedited
GACCGGGTTTNGTAAACCGCACTCATGAGAGGGCGGCAAACACAATTCGCACGAGCTTTG CCCCAAAACTCTTTCCTTTGGTTGTGCTAAGAGGTGATGCCCAAGGTGCACCACCTTTCA AGAACTGGATCATGAACAACTTTATCCTCCTGGAAGAACAGCTCATCAAGAAATCCCAAC AAAAGAGAAGAACTTCTCCCTCGAACTTTAAAGTCCTCTTCNTTGTGTTAACCAAAGCCA GCCTGGCATACTTTGAAGATCGTCATGGGAAGAAGCGCACGCTGAAGGGGTCCATTGAGC TCTCCCGAATCAAATGTGTTGAGATTGTGAAAAGTGACATCAGCATCCCATGCCACTATA AATACCCGTTTCAGGTGGTGCATGACAACTACCTCCTATATGTGTTTGCTCCAGATCGTG AGAGCCGGCAGCGCTGGGTGCTGGCCCTTAAAGAAGAAACGAGGAATAATAACAGTTTGG TGCCTAAATATCATCCTAATTTCTGGATGGATGGGAAGTGGAGGTGCTGTTCTCAGCTGG AGAAGCTTGCAACAGGCTGTGCCCAATATGATCCAACCAAGAATGCTTCAAAGAAGCCTC TTCCTCCTACTCCTGAAGACAACAGGCGACCACTTTGGGAACCTGAAGAAACTGTGGTCA TTGCCTTATATGACTACCAAACCAATGATCCTCAGGAACTCGCACTGCGGCGCAACGAAG AGTACTGCCTGCTGGACAGTTCTGAGATTCACTGGTGGAGAGTCCAGACAGGAATGGGCA TGAAGGATATGTACCAAGCAGTTATCTGGTGGAAAAATCTCCAAATAATCTGGAAACCTA TGAGTGGTACAATAAGAGTATCAGCCGAGACCAAGGCTGAAAACTTCTTTTGGACACNGC CAAGAAGGAGCCTTC >OriGene 3' read for NM_005546 unedited
TTTAAATAGCTTGNNACCGCGGCCGCAATCTAGNGATCGGTTTTTTTTTTTTTTTTTTTT TATTTGTAACATTTTTATTTTGAACACTAGCAGTGACTGTACATTAATAAATATGCATCT GATCCAAATATAAATACATAGTCTCAAAAGGTACAAAATGCAAAATCTACGAAATAAAAC TAGAACCAAAACTCTGTATAAGGGAGTTCTCTACAAACACAGGGGACCATTTAAAAAATG TGAGAAGAGAAAAACCAGGCAGGAAGCCCATTTTGCGGGATAGGGCACCAGGAGGTGAAG AATGTACACATGTACAGTTGAGGATTAGATGAATCTGAGCTTGAAAAAGGTAATACCATG CACAGGGGAATTTTCTAAACCAAACCACAGAGATCAGTCAATTCCAATGTTTTCTTTCTA GACTGAATGTTCCAGAAATCATCTCTAATTAAGGATCCCAAAAGATAATGTACAAAATTC TAAAAAGTAAACAGAGATAATTTTGGATAAGCTGAGTAAAATCATCTTCTGAATGACAGA GTTTTATCTTGAGGCTCTCCACTTCACAATAATTATAATTAAAAATTATGCATCTGAATC TCAAGCCAGTCAAAACGTCACATGATTTAGAAAGAGCCAATTGCAACACCATCCTCTCTT ATATCAGGGAATGTCCCTCCTCATGAAGTGTTCAAGAAGACTACAGCTGAAAGTTGGAAT GATAATTAAAGGAAGAACTCATACTTCTACAGAAGAATCTTTTAAAGTTGCTTTGAAGCT CGTCTATAAATGGCTTCAAGCAACATGACTGGTTGGTTGTGAAGATTAAAGGGTCATTAA CTGAATAACTCCAAAGTCATTAACATGACCCAAGTANGGATACAGAATANNGAAAAGGAA AATCCTATTNCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005546 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005546.3, NP_005537.3 |
| RefSeq Size | 4366 bp |
| RefSeq ORF | 1863 bp |
| Locus ID | 3702 |
| UniProt ID | Q08881 |
| Domains | pkinase, SH2, TyrKc, SH3, BTK, PH, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Leukocyte transendothelial migration, T cell receptor signaling pathway |
| Gene Summary | This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216092 | ITK (Myc-DDK-tagged)-Human IL2-inducible T-cell kinase (ITK) |
CNY 6,920.00 |
|
| RC216092L1 | Lenti ORF clone of Human IL2-inducible T-cell kinase (ITK), Myc-DDK-tagged |
CNY 9,320.00 |
|
| RC216092L2 | Lenti ORF clone of Human IL2-inducible T-cell kinase (ITK), mGFP tagged |
CNY 6,460.00 |
|
| RC216092L3 | Lenti ORF clone of Human IL2-inducible T-cell kinase (ITK), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC216092L4 | Lenti ORF clone of Human IL2-inducible T-cell kinase (ITK), mGFP tagged |
CNY 6,460.00 |
|
| RG216092 | ITK (tGFP-tagged) - Human IL2-inducible T-cell kinase (ITK) |
CNY 8,520.00 |
|
| SC323603 | ITK (untagged)-Kinase deficient mutant (K391M) of Human IL2-inducible T-cell kinase (ITK) |
CNY 4,624.00 |
