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NDUFV1 (NM_007103) Human Untagged Clone
CAT＃: SC115721
NDUFV1 (untagged)-Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CI-51K; CI51KD; MC1DN4; UQOR1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115721 sequence for NM_007103 edited (data generated by NextGen Sequencing)
ATGCTGGCAACACGGCGGCTGCTCGGCTGGTCGCTTCCCGCGCGGGTATCTGTGCGTTTC AGCGGCGACACGACAGCACCCAAGAAAACCTCATTTGGCTCGCTGAAGGATGAAGACCGG ATTTTCACCAACCTGTACGGCCGCCATGACTGGAGGCTGAAAGGTTCCCTGAGTCGAGGT GACTGGTACAAGACAAAGGAGATCCTGCTGAAGGGGCCCGACTGGATCCTGGGCGAGATC AAGACATCGGGTTTGAGGGGCCGTGGAGGCGCTGGCTTCCCCACTGGCCTCAAGTGGAGC TTCATGAATAAGCCCTCAGATGGCAGGCCCAAGTATCTGGTGGTGAACGCAGACGAGGGG GAGCCGGGCACCTGCAAGGACCGGGAGATCTTACGCCATGATCCTCACAAGCTGCTGGAA GGCTGCCTGGTGGGGGGCCGGGCCATGGGCGCCCGCGCTGCCTATATCTACATCCGAGGG GAATTCTACAATGAGGCCTCCAATCTGCAGGTGGCCATCCGAGAGGCCTATGAGGCAGGT CTGATTGGCAAGAATGCTTGTGGCTCTGGCTATGATTTTGACGTGTTTGTGGTGCGCGGG GCTGGGGCCTACATCTGTGGAGAGGAGACAGCGCTCATCGAGTCCATTGAGGGCAAGCAG GGCAAGCCCCGCCTGAAGCCCCCCTTCCCCGCAGACGTGGGAGTGTTTGGCTGCCCCACA ACTGTGGCCAACGTGGAGACAGTGGCAGTGTCCCCCACAATCTGCCGCCGTGGAGGTACC TGGTTTGCTGGCTTTGGCAGAGAACGCAACTCAGGCACCAAACTATTCAACATCTCTGGC CATGTCAACCACCCTTGCACTGTGGAGGAGGAGATGTCTGTGCCCTTGAAAGAACTGATT GAGAAGCATGCTGGGGGTGTCACGGGCGGCTGGGACAACCTCCTTGCTGTGATCCCTGGC GGCTCGTCTACCCCACTGATCCCCAAGTCTGTGTGTGAGACGGTGCTGATGGACTTCGAT GCGCTGGTGCAGGCACAGACAGGCCTGGGCACAGCTGCGGTGATCGTCATGGACCGCTCG ACGGACATCGTGAAAGCCATCGCCCGCCTCATTGAGTTCTATAAGCACGAGAGCTGTGGC CAGTGTACCCCATGCCGTGAGGGTGTGGACTGGATGAACAAGGTGATGGCACGTTTCGTG AGGGGGGATGCCCGGCCGGCCGAGATCGACTCCCTGTGGGAGATCAGCAAGCAGATAGAA GGCCATACGATTTGTGCTCTGGGTGACGGGGCCGCCTGGCCTGTGCAGGGTCTGATCCGC CACTTTCGGCCGGAGCTCGAGGAGCGGATGCAGCGGTTTGCCCAGCAGCATCAGGCCCGG CAGGCTGCCTCTTAG Clone variation with respect to NM_007103.3 >OriGene 5' read for NM_007103 unedited
GTTTCAGNATATTTGTATACCATCTCCTATAGGCGGCCGCCGAATTCGCACGAGGCGTGA GGTGACCCATCTGGCCCGCCGCGATGCTGGCAACACGGCGGCTGCTCGGCTGGTCGCTTC CCGCGCGGGTATCTGTGCGTTTCAGCGGCGACACGACAGCACCCAAGAAAACCTCATTTG GCTCGCTGAAGGATGAAGACCGGATTTTCACCTTTCTGTACGGCCGCCATGACTGGAGGC TGAAAGGTTCCCTGAGTCGAGGTGACTGGTACAAGACAAAGGAGATCCTGCTGAAGGGGC CCGACTGGATCCTGGGCGAGATCAAGACATCGGGTTTGAGGGGCCGTGGAGGCGCTGGCT TCCCCACTGGCCTCAAGTGGAGCTTCATGAATAAGCCCTCAGATGGCAGGCCCAAGTATC TGGTGGTGAACGCAGACGAGGGGGAGCCGGGCACCTGCAAGGACCGGGAGATCTTACGCC ATGATCCTCACAAGCTGCTGGAAGGCTGCCTGGCGGGGGGCCGGGCCATGGCCGCCCGCG CTGCCTATATCTACATCCGAGGGGAATTCTAACAATGAGGCCTCCAATCTGCACGCGGCC ATCCGAGAGGCCTATGAGGCAGGTCTGATTGCCAAGAATGCTTGCGGCTCTGGCTATGAC TTCGACGCGCTTGTGGTGCGCGGGGCTGGGGCCTACATCTGCGGCAAGGAGACAGCGCTC ATCCTACCCCTTGACGGCAAGAAGGCCAAGCCCCGCCTGAAGCCCCCCTTCCCCGAATAC CTGGGAGTGTTTGGCTGCCCCCCACTGTGGGCACCTGGAAACAGTGGCGGGGCCCCCACA ATCTGCCGCCGCGAAGTACCCGTTCTCCTGCTCTGGCCAAAACCCACCCAGCCCCAACTA TTCCAAAACTCGGCG >OriGene 3' read for NM_007103 unedited
AAACCACANCCCCCCCCCCCCCNNTAANNNNNNNAANNTTTGACTTTGNACCGCGGNCCG CATACTGNGATCGNGTTTTTTTTTTTTTTTTTTGGGAGGTGGGCAGCACTCGCTTNTATG TCCAGCATTCCACATGGGTAGACGCAGGACAGCAGGCCAGGGTGGTGGGCTAAGAGGCAG CCTGCCGGGCCTGATGCTGCTGGGCAAACCGCTGCATCCGCTCCTCGAGCTCCGGCCGAA AGTGGCGGATCAGACCCTGCACAGGCCAGGCGGCCCCGTCACCCAGAGCACAAATCGTAT GGCCTTCTATCTGCTTGCTGATCTCCCACAGGGAGTCGATCTCGGCCGGCCGGGCATCCC CCCTCACGAAACGTGCCATCACCTTGTTCATCCAGTCCACACCCTCACGGCATGGGGTAC ACTGGCCACAGCTCTCGTGCTTATAGAACTCAATGAGGCGGGCGATGGCTTTCACGATGT CCGTCGAGCGGTCCATGACGATCACCGCAGCTGTGCCCAGGCCTGTCTGTGCCTGCACCA GCGCATCGAAGTCCATCAGCACCGTCTCACACACAGACTTGGGGATCAGTGGGGTAGACG AGCCGCCAGGGATCACAGCAAGGAGGTTGTCCCAGCCGCCCGTGACACCCCCAGCATGCT TCTCAATCAGTTCTTTCAAGGGCACAGACATCTCCTCCTCCACAGTGCAGGGGTGGTTGA CATGGCCAGAGATGTTGAATAGTTTTGTGCCTGAGTTGCGTTCTCTGCCAAAGCCAGCAA ACCAGGTACCTTCACGGCGGCCAGATTGTGGGGGACACTGCCACTGTCTCCACGTNGCCA CAGTTGTGGGGCAGCCAAACACTCCACGTTTGNGGGGAAGGGGGGCTCAGCCGGGGCTTG CCCTNCTTGCCCTCAATGCATCCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_007103 |
| Insert Size | 1570 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007103.2, NP_009034.2 |
| RefSeq Size | 1566 bp |
| RefSeq ORF | 1395 bp |
| Locus ID | 4723 |
| UniProt ID | P49821 |
| Domains | Complex1_51K |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
| Gene Summary | The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Granzyme B-induced mitochondrial ROS are required for apoptosis
,Jacquemin, G;Margiotta, D;Kasahara, A;Bassoy, EY;Walch, M;Thiery, J;Lieberman, J;Martinvalet, D;,
Cell Death Differ.
,PubMed ID 25361078
[NDUFV1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204954 | NDUFV1 (Myc-DDK-tagged)-Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,656.00 |
|
| RC204954L3 | Lenti ORF clone of Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204954L4 | Lenti ORF clone of Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG204954 | NDUFV1 (tGFP-tagged) - Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 5,256.00 |
|
| SC320461 | NDUFV1 (untagged)-Human NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (NDUFV1), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,656.00 |
