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NCOA62 (SNW1) (NM_012245) Human Untagged Clone
CAT＃: SC115506
SNW1 (untagged)-Human SNW domain containing 1 (SNW1)
CNY 4,000.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Bx42; FUN20; NCOA-62; Prp45; PRPF45; SKIIP; SKIP; SKIP1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_012245 edited
GCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGT AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTCGCGCTGGAAGAAGCG GAAGAAGATGGCGCTCACCAGCTTTTTACCTGCACCTACTCAGCTATCTCAGGACCAGCT TGAGGCTGAAGAAAAGGCAAGATCCCAGAGATCACGGCAGACCTCACTGGTCTCCTCCCG AAGAGAACCTCCCCCGTACGGATACCGGAAAGGCTGGATACCTCGGTTATTAGAGGATTT TGGAGATGGAGGTGCTTTTCCAGAGATCCATGTGGCCCAGTATCCACTGGATATGGGACG AAAGAAAAAAATGTCGAATGCGCTGGCCATTCAGGTGGATTCTGAAGGAAAAATTAAATA TGATGCAATTGCTCGACAAGGACAGTCAAAAGACAAGGTCATTTATAGCAAATACACTGA CCTGGTTCCAAAGGAGGTTATGAATGCAGATGATCCAGACCTGCAAAGGCCCGATGAAGA AGCTATTAAAGAGATAACAGAAAAGACAAGAGTAGCCTTAGAAAAATCTGTATCACAGAA GGTCGCCGCAGCCATGCCAGTTCGAGCAGCTGACAAATTGGCTCCTGCTCAGTATATCCG ATACACACCATCTCAGCAAGGAGTGGCATTCAACTCTGGAGCTAAACAGAGGGTTATTCG GATGGTAGAAATGCAGAAAGATCCAATGGAGCCTCCAAGGTTCAAGATTAATAAGAAAAT TCCCCGGGGACCACCTTCTCCTCCTGCGCCTGTCATGCATTCTCCTAGCCGAAAGATGAC TGTAAAGGAACAACAAGAGTGGAAGATTCCTCCTTGTATTTCTAACTGGAAAAATGCAAA GGGTTATACAATTCCATTAGACAAACGTCTGGCTGCTGATGGAAGAGGACTACAGACAGT ACACATAAATGAAAATTTCGCCAAATTGGCAGAAGCCCTCTACATTGCTGATCGGAAGGC TCGTGAAGCTGTGGAAATGCGTGCCCAAGTAGAGAGAAAAATGGCTCAGAAAGAAAAGGA AAAACATGAAGAGAAACTTAGAGAAATGGCCCAGAAAGCCAGGGAAAGAAGAGCTGGGAT CAAAACTCATGTGGAAAAAGAGGATGGGGAGGCACGTGAGAGGGATGAAATCCGGCATGA CAGGCGAAAAGAGAGACAGCATGACCGGAATCTTTCCAGGGCAGCTCCTGATAAGAGGTC GAAACTTCAGAGAAATGAAAATCGGGATATCAGTGAAGTTATTGCTCTCGGTGTTCCTAA TCCTCGGACTTCCAATGAAGTTCAGTATGACCAAAGGCTCTTCAACCAATCCAAGGGTAT GGACAGTGGATTTGCAGGTGGAGAAGATGAAATTTATAATGTTTATGATCAAGCCTGGAG AGGTGGTAAAGATATGGCCCAGAGTATTTATAGGCCCAGTAAAAATCTGGACAAGGACAT GTATGGTGATGACCTAGAAGCCAGAATAAAGACCAACAGATTTGTTCCCGACAAGGAGTT TTCTGGTTCAGACCGTAGACAGAGAGGCCGAGAAGGACCAGTTCAGTTTGAGGAAGATCC TTTTGGTTTGGACAAGTTTTTGGAAGAAGCCAAACAGCATGGTGGCTCTAAAAGACCCTC AGATAGCAGCCGCCCCAAGGAACACGAGCATGAAGGCAAGAAGAGGAGGAAGGAATAGGC ACAGGTCTCTCCAAAGTGAATGAACTCTTACCCATAACCCTAATGATGCAAGTCATATGG GGGAACACTTTGTAAATGGTCAGGATAAAAACCAAATCTGGGTGCCAGATCCCAGCACTA CTTTTTATTACTGGAGAAATGGGGGGGATAGAAAATTCTACTTTGAATTATTTAGTTTTT TTTAAAGAGTGGGTTGTGTTTGTGCTTCTCCCACCTTTCAGCATTTATAGAACATGCTGC CCCACATACAAAGTCAAGACCACTTACTTTTATGTGACACTAGTAGTTTGGGGTTAATGT TTTGTGTAAGAACAGCTGCATATGAGTAAAGTTACCCCAACCACAGTGAGGAGGAAGATG TTCACATACTGGAACTGTCCTGCCAAATAAATTTTGCCCCTATTGTGCTCTGTTTTAATT TGGAGTGGGCAAAGTAACCTCTTGCTTGGTGCAACTATTTGTTTCAAATAAAAACATTTA GACAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCT GAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCT >OriGene 5' read for NM_012245 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTCGCGCTGGAAGAAG CGGAAGAAGATGGCGCTCACCAGCTTTTTACCTGCACCTACTCAGCTATCTCAGGACCAG CTTGAGGCTGAAGAAAAGGCAAGATCCCAGAGATCACGGCAGACCTCACTGGTCTCCTCC CGAAGAGAACCTCCCCCGTACGGATACCGGAAAGGCTGGATACCTCGGTTATTAGAGGAT TTTGGAGATGGAGGTGCTTTTCCAGAGATCCATGTGGCCCAGTATCCACTGGATATGGGA CGAAAGAAAAAAATGTCGAATGCGCTGGCCATTCAGGTGGATTCTGAAGGAAAAATTAAA TATGATGCAATTGCTCGACAAGGACAGTCAAAAGACAAGGTCATTTATAGCAAATACACT GACCTGGTTCCAAAGGAGGTTATGAATGCAGATGATCCAGACCTGCAAAGGCCCGATGAA GAAGCTATTAAAGAGATAACAGAAAAGACAAGAGTAGCCTTAGAAAAATCTGTATCACAG AAGGTCGCCGCAGCCATGCCAGTTCGAGCAGCTGACAAATTGGCTCCTGCTCAGTATATC CGATACACACCATCTCAGCAAGGAGTGGCATTCAACTCTGGAGCTAAACAGAGGGTTATT CGGATGGTAGAAATGCAGAAAGATCCAATGGAGCCTCCAAGGTTCAAGATTAATAAGAAA ATTCCCCGGNGACCACCTTCTCCTCCTGCGCCTGTCATGCATTCTCCTAGCCGAAAATGA CTGGTAAGGAACCAACAGAGTGGAAGAATCCTCCTTGTATTTCTACTGGAAAATGCAAAG GTTATACANTNCATTAGACAACGTCTGCTGCTGATGGNAGAGACTACGACGTCACATAAT GAAAATTCCCAANTGCAGAGCCTCTACTTGTGATCGAAGCTGTGAA >OriGene 3' read for NM_012245 unedited
NNNNCCTTACTTGNNACCGCGGCCGCTTTCTAGNATCGAGTTTTTTTTTTTTTTTTTTGT CTAAAGTTTTTATTTGAAACAAATAGTTGCACCAAGCAAGAGGTTACTTTGCCCACTCCA AATTAAAACAGAGCACAATAGGGGCAAAATTTATTTGGCAGGACAGTTCCAGTATGTGAA CATCTTCCTCCTCACTGTGGTTGGGGTAACTTTACTCATATGCAGCTGTTCTTACACAAA ACATTAACCCCAAACTACTAGTGTCACATAAAAGTAAGTGGTCTTGACTTTGTATGTGGG GCAGCATGTTCTATAAATGCTGAAAGGTGGGAGAAGCACAAACACAACCCACTCTTTAAA AAAAACTAAATAATTCAAAGTAGAATTTTCTATCCCCCCCATTTCTCCAGTAATAAAAAG TAGTGCTGGGATCTGGCACCCAGATTTGGTTTTTATCCTGACCATTTACAAAGTGTTCCC CCATATGACTTGCATCATTAGGGTTATGGGTAAGAGTTCATTCACTTTGGAGAGACCTGT GCCTATTCCTTCCTCCTCTTCTTGCCTTCATGCTCGTGTTCCTTGGGGCGGCTGCTATCT GAGGGTCTTTTAGAGCCACCATGCTGTTTGGCTTCTTCCAAAAACTTGTCCAAACCAAAA GGATCTTCCTCAAACTGAACTGGTCCTTCTCGGCCTCTCTGTCTACGGTCTGAACCAGAA AACTCCTTGTCGGNAACANATCTNGTGGTCTTTATTCTGGCTTCTANGTCATCACCCTAC ATGTTCCTTGNCCAGATTTTTACTGGGCCTATAAATACTCTGGGCCATATCTTTACCACC TCCTCCAGCTTGATCATAAACATTATAAATTCATCTTCTCCACTGCAAANCACTGTCCAT ACCTNGGATGGNTGAANAGCTTTGNC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012245 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012245.2, NP_036377.1 |
| RefSeq Size | 2146 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 22938 |
| UniProt ID | Q13573 |
| Domains | SKIP_SNW |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Notch signaling pathway, Spliceosome |
| Gene Summary | This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (2) differs in the 3' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215046 | SNW1 (Myc-DDK-tagged)-Human SNW domain containing 1 (SNW1) |
CNY 3,990.00 |
|
| RC215046L1 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215046L2 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), mGFP tagged |
CNY 5,890.00 |
|
| RC215046L3 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC215046L4 | Lenti ORF clone of Human SNW domain containing 1 (SNW1), mGFP tagged |
CNY 5,890.00 |
|
| RG215046 | SNW1 (tGFP-tagged) - Human SNW domain containing 1 (SNW1) |
CNY 4,370.00 |
