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ALIX (PDCD6IP) (NM_013374) Human Untagged Clone
CAT＃: SC115270
PDCD6IP (untagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AIP1; ALIX; DRIP4; HP95 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115270 sequence for NM_013374 edited (data generated by NextGen Sequencing)
ATGGCGACATTCATCTCGGTGCAGCTGAAAAAGACCTCAGAGGTGGACCTGGCCAAGCCG CTGGTGAAGTTCATCCAGCAGACTTACCCAAGCGGCGGGGAAGAGCAGGCCCAGTACTGC CGCGCGGCGGAGGAGCTCAGCAAGCTGCGCCGCGCCGCAGTCGGTCGTCCGCTGGACAAG CACGAGGGCGCGCTCGAGACGCTCCTGAGATATTATGATCAGATTTGTTCTATTGAACCC AAATTCCCATTTTCTGAAAATCAGATCTGCTTGACATTTACCTGGAAGGATGCTTTCGAT AAAGGTTCACTTTTTGGAGGCTCTGTAAAACTGGCTCTTGCAAGCTTAGGATATGAAAAG AGCTGTGTGTTGTTCAATTGTGCAGCCTTAGCTAGCCAAATTGCAGCAGAACAGAACCTG GATAATGATGAAGGATTGAAAATCGCTGCTAAACATTACCAGTTTGCTAGTGGTGCCTTT TTACATATTAAAGAGACGGTTTTATCTGCCTTAAGTCGAGAGCCGACCGTGGACATATCT CCAGATACTGTTGGGACCCTCAGTCTTATTATGCTGGCACAGGCTCAAGAAGTATTTTTT TTAAAAGCCACAAGAGATAAAATGAAAGATGCCATCATAGCTAAATTGGCTAATCAGGCT GCAGATTATTTTGGTGATGCTTTCAAACAGTGTCAATACAAAGATACTCTCCCCAAGGAG GTGTTCCCTGTCTTGGCTGCAAAGCACTGTATCATGCAGGCCAATGCTGAGTACCATCAG TCTATCCTGGCAAAACAGCAGAAGAAATTTGGAGAAGAAATTGCAAGGTTACAGCATGCA GCAGAACTGATTAAAACAGTGGCATCTCGCTATGATGAATATGTTAATGTGAAGGATTTT TCTGACAAAATCAATCGTGCCCTTGCTGCAGCAAAGAAGGATAATGACTTCATTTATCAT GATCGAGTTCCAGACCTTAAAGATCTAGATCCTATTGGCAAAGCCACACTTGTGAAATCT ACCCCGGTCAATGTACCCATCAGTCAGAAATTTACTGATCTGTTTGAGAAGATGGTTCCC GTGTCAGTACAGCAGTCTTTGGCTGCCTATAATCAGAGGAAAGCCGATTTGATTAACAGA TCAATTGCTCAGATGAGAGAAGCCACCACTTTGGCAAATGGGGTGCTAGCTTCCCTTAAT CTTCCAGCAGCAATTGAAGATGTGTCTGGAGACACTGTACCTCAGTCTATATTGACTAAA TCCAGATCTGTGATTGAACAGGGAGGCATCCAGACTGTTGATCAGTTGATTAAAGAACTG CCTGAATTACTGCAACGAAATAGAGAAATCCTAGATGAGTCATTAAGGTTGTTGGATGAA GAAGAAGCAACCGATAATGATTTAAGAGCAAAATTTAAGGAACGTTGGCAAAGGACACCA TCCAATGAACTGTATAAGCCTTTAAGAGCAGAGGGAACCAACTTCAGAACAGTTTTAGAT AAAGCTGTGCAGGCAGATGGACAAGTGAAAGAATGTTACCAGTCTCATCGTGACACCATC GTGCTTTTGTGTAAGCCAGAGCCTGAGCTGAATGCTGCCATCCCTTCTGCTAATCCAGCA AAGACCATGCAGGGCAGTGAGGTTGTAAGTGTCTTAAAATCCTTATTGTCAAATCTTGAT GAAGTAAAGAAGGAAAGAGAGGGTCTGGAGAATGACTTGAAATCTGTGAATTTTGACATG ACAAGCAAGTTTTTGACAGCCCTGGCTCAAGATGGTGTGATAAATGAAGAAGCTCTTTCT GTTACTGAACTAGATCGAGTCTATGGAGGTCTTACAACTAAAGTCCAAGAATCTCTAAAG AAACAGGAGGGACTTCTTAAAAATATTCAGGTCTCACATCAGGAATTTTCAAAAATGAAA CAATCTAATAATGAAGCTAACTTAAGAGAAGAAGTTTTGAAGAATTTAGCTACTGCATAT GACAACTTTGTTGAACTTGTAGCTAATTTGAAGGAAGGCACAAAGTTTTACAATGAGTTG ACTGAAATCCTGGTCAGGTTCCAGAACAAATGCAGTGATATAGTTTTTGCACGGAAGACA GAAAGAGATGAACTCTTAAAGGACTTGCAACAAAGCATTGCCAGAGAACCTAGTGCTCCT TCAATTCCTACACCTGCGTATCAGTCCTCACCAGCAGGAGGACATGCACCAACTCCTCCA ACTCCAGCGCCAAGAACCATGCCGCCTACTAAGCCCCAGCCCCCAGCCAGGCCTCCACCA CCTGTGCTTCCAGCAAATCGAGCTCCTTCTGCTACTGCTCCATCTCCAGTGGGGGCTGGG ACTGCTGCGCCAGCTCCATCACAAACGCCTGGCTCAGCTCCTCCTCCACAGGCGCAGGGA CCACCCTATCCCACCTATCCAGGATATCCTGGGTATTGCCAAATGCCCATGCCCATGGGC TATAATCCTTATGCGTATGGCCAGTATAATATGCCATATCCACCAGTGTATCACCAGAGT CCTGGACAGGCTCCGTACCCGGGACCCCAGCAGCCTTCATACCCCTTCCCTCAGCCCCCA CAGCAGTCTTACTATCCACAGCAGTAA Clone variation with respect to NM_013374.4 1132 g=>a;1649 a=>g;2535 a=>g >OriGene 5' read for NM_013374 unedited
GTTCACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTGTCAGCCA GTCAGTCCGCCAGTCCGCCAGCCCAGTACCTCTCTCTCCTCGGCCCTCGTAAGCTGTCCG CGGTCTGTTTGGCCCGAACGGCGGCGGAGGCGCTGATCATGGCGACATTCATCTCGGTGC AGNCTGAAAAAGACCTCAGAGGTGGACCTGGCCAAGCCGCTGGTGAAGTTCATCCAGCAG ACTTACCCAAGCGGCGGGGAAGAGCAGGCCCAGTACTGCCGCGCGGCGGAGGAGCTCAGC AAGCTGCGCCGCGCCGCAGTCGGTCGTCCGCTGGACAAGCACGAGGGCGCGCTCGAGACG CTCCTGAGATATTATGATCAGATTTGTTCTATTGAACCCAAATTCCCATTTTCTGAAAAT CAGATCTGCTTGACATTTACCTGGAAGGATGCTTTCGATAAAGGTTCACTTTTTGGAGGC TCTGTAAAACTGGCTCTTGCAAGCTTAGGATATGAAAAGAGCTGTGTGTTGTTCAATTGT GCAGCCTTAGCTAGCCAAATTGCAGCAGAACAGAACCTGNATAATGATGAAGGATTGAAA ATCGCTGCTAAACATTACCAGTTTGCTAGTGGTGCCTTTTTACATATTAAAGAGACGGTT NTATCTGCCTTAAGTCGAGAGCCGACCGTGGACATATCTCCAGATACTGTTGGGACCCTC AGTCTTATTATGCTGGCACAGGCTCAAGAAGTATTTTTTTTTAAAGCCACAAGAGATAAA TGAAAGATGCCATCATAGCTAAATGGNCTAATCANGCTGCAGATATTTTGGTGATGCCTT CAAACAGTGTCAATACAAAGATACTCTCCCCAAGGNNAGTGTCCCTGTCTTGGCTGCAAG CACTGTATCATGCAG >OriGene 3' read for NM_013374 unedited
TGGACGCGGCCGCAATCTAGAGTCGAGGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTAACGGGTCTTAAGAAATTTATTTTAAAATTATAAAATTTACAGGGCCTTGATT ATGCAAAATAGCATAATGGAAATTAAACCAAATCAATAAACCAAAGAGAAAGAAAACTTA ATTTTCTTTAGTATCCATACTTAAACCATTTTTGTAAGTATCTGATGTCCCAACCATGTT TTATGTAAAAAGTATAATCGTTTCAAAGGTTTCACTTGCAGGTTAAATTTCTCATTTTCA ATTTTTATGAACTGTAATGCAATTTCAAATCCTATTATACCTAGGGTTTATACTGCAACA GCAGCAAATCTCACATGGGTAATCAAATGGGGAACTGGGGCACAGCTTCTAGCTGTAAAC AGAAATTATACACTGCATTCAGTCCAGGAGAGTACATTACATTAACCAGAGCGTAGAGTT TAGTACACTTATTGCAGGGCGGGTATTTCTTTCCCTCTGATCTGAATCAGCTGAGCTGGT GAGCAGACATATTACTGCTGGGGATAGTAAAACTGCTGTGGGGGCTGAGGGAAGGGGTAT GAAGGCTGCTGGGGTCCCGGGTATGGAGCCCTGTCCAGCACTCTGGAGATACACTGGGGG ATATGGAATATTATACTGCCCATACGCATAAGGATTATAGCCCCATGGGCCATGGCGATT TGGAAATACCCAGGATATTCTGAAAAGGTGGGAAAAGGGTGGCCCCTGCCCCTGTGGAGG AGGAGCTGACCACGCCGTTGAGAGGAACTTGCGCCACATTCCCAGCCCCCATGTAGATGG AACATAACAAAAGGACCTCGATTTGCTGGAAACACAGGGGTGGAGCCTGGCTGGGGCTGG GCTTAAAAGCGGATGGCCTTGTGCCCGAATTGGAGGAATTGCGCATGTCCTCTGCGGAGA GACTGAACCCAGTGTAGGATAGAAG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_013374 |
| Insert Size | 3330 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_013374.3, NP_037506.2 |
| RefSeq Size | 6448 bp |
| RefSeq ORF | 2607 bp |
| Locus ID | 10015 |
| UniProt ID | Q8WUM4 |
| Domains | BRO1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
| Gene Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] Transcript Variant: This variant (1) uses an alternate in-frame splice site in the central coding region, compared to variant 2, resulting in an isoform (1) that is shorter than isoform 2. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203735 | PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 3,990.00 |
|
| RC203735L1 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203735L2 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203735L3 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203735L4 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG203735 | PDCD6IP (tGFP-tagged) - Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 4,370.00 |
|
| SC323909 | PDCD6IP (untagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 2,950.00 |
