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CTPS2 (NM_019857) Human Untagged Clone
CAT＃: SC113217
CTPS2 (untagged)-Human CTP synthase II (CTPS2), transcript variant 1
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GATD5B |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC113217 sequence for NM_019857 edited (data generated by NextGen Sequencing)
ATGAAGTACATCCTGGTCACGGGTGGGGTCATCTCAGGCATTGGTAAAGGGATCATTGCC AGCAGCATTGGAACGATTCTAAAATCATGTGGACTCCGAGTTACTGCCATAAAAATCGAC CCCTATATTAACATCGATGCTGGCACTTTTTCACCTTATGAACACGGTGAAGTCTTCGTC TTAAATGATGGTGGAGAAGTTGATTTAGACCTTGGAAATTATGAAAGATTTTTGGATATT AATCTTTATAAAGACAACAATATCACCACGGGGAAGATATATCAGCATGTGATCAATAAA GAGAGGCGTGGTGATTACCTGGGGAAAACAGTGCAAGTTGTCCCTCACATTACTGATGCT GTCCAGGAGTGGGTTATGAATCAAGCCAAGGTGCCGGTGGATGGTAATAAGGAAGAGCCC CAAATATGCGTTATTGAGCTGGGAGGCACCATTGGAGACATCGAAGGAATGCCGTTTGTG GAGGCGTTTAGACAATTCCAGTTTAAGGCGAAAAGAGAGAATTTCTGTAATATCCACGTT AGCCTTGTCCCACAGCTCAGTGCTACCGGAGAACAAAAAACCAAACCCACCCAAAACAGC GTCCGCGCACTGAGGGGTTTAGGCCTGTCTCCAGATCTGATTGTCTGCCGAAGTTCAACG CCCATTGAGATGGCCGTGAAGGAGAAGATTTCTATGTTTTGTCACGTGAACCCTGAACAG GTCATATGTATCCATGATGTTTCTTCCACATACCGAGTTCCTGTGCTTTTAGAGGAACAA AGCATTGTGAAATATTTTAAGGAGAGATTGCACCTGCCCATCGGTGATTCTGCAAGTAAT TTGCTTTTTAAGTGGAGAAATATGGCTGACAGGTATGAAAGGTTACAGAAAATATGCTCC ATAGCCCTGGTTGGCAAATACACCAAGCTCAGAGACTGCTACGCCTCTGTGTTCAAAGCC CTGGAACACTCAGCCCTGGCCATCAACCACAAGTTGAATCTGATGTACATAGACTCCATT GATCTGGAGAAGATCACTGAAACCGAGGACCCTGTGAAATTTCATGAAGCTTGGCAGAAG CTATGCAAAGCTGATGGTATTCTTGTGCCTGGAGGCTTTGGAATCAGAGGAACATTGGGA AAACTCCAGGCGATTTCTTGGGCAAGGACAAAGAAGATTCCTTTTCTGGGAGTTTGTCTT GGGATGCAACTAGCAGTGATAGAGTTTGCAAGAAACTGCCTTAACTTGAAAGATGCTGAT TCCACAGAGTTTAGGCCAAATGCCCCAGTTCCTCTGGTGATTGATATGCCCGAGCACAAC CCTGGCAATTTGGGAGGAACAATGAGACTGGGAATAAGAAGAACTGTTTTCAAAACTGAA AATTCAATATTAAGGAAACTTTATGGTGATGTTCCTTTTATAGAAGAAAGACACAGACAT CGGTTCGAGGTAAACCCTAACCTGATCAAACAATTTGAGCAGAATGACTTAAGTTTTGTA GGTCAGGATGTTGATGGAGACAGGATGGAAATCATTGAACTGGCAAATCATCCTTATTTT GTTGGTGTCCAGTTCCATCCTGAGTTTTCTTCTAGGCCGATGAAGCCTTCCCCTCCGTAT CTGGGGCTGTTACTTGCAGCAACTGGGAACCTGAATGCCTACTTGCAACAGGGTTGCAAA CTGTCTTCCAGTGATAGATACAGTGATGCCAGTGATGACAGCTTTTCAGAGCCAAGGATA GCTGAGTTGGAAATAAGCTGA Clone variation with respect to NM_019857.3 >OriGene 5' read for NM_019857 unedited
NTGTTCAAATTTTTGTATACGACTCACTATTAGGGCGGCCGCGATTCGGCACCAGAACGG GAGCTGCCTGTGCTGGAGGAATCACTTTTTAGGCGCTTGTTTTGGACCATTGCACAAACC CGGGTGCAAACCCCAAGCTCACCAGCCCCGACAGGTGAGCGCCAGGCCAGCCGCGGGGTG GAGCCCGCCGTGCCCACCGGCCACCCTCCCCGGTGCTACCACCACCGCGCAGACGGAGTC TCACTCTGTTGTCCAGACTGGAGTGCAATGGTGTGATCTTGGCTCTGGGTTTGGATTGAC AATGTTTTAAGCTATAAACATAGGTCAGATAGATTATATCTGGGTGTTGGCACCCAGCCA CTATTCTGCCAATGAAGTACATCCTGGTCACGGGTGGGGTCATCTCAGGCATTGGTAAAG GGATCATTGCCAGCAGCATTGGAACGATTCTAAAATCATGTGGACTCCGAGTTACTGCCA TAAAAATCGACCCCTATATTAACATCGATGCTGGCACTTTTTCACCTTATGAACACGGTG AAGTCTTCGTCTTAAATGATGGTGGAGAAGTTGATTTAGACCTTGGAAATTATGAAAGAT TTTTGGATATTAATCTTTATAAAGACAACAATATCACCACGGNGAAGATATATCAGCATG TGATCAATAAAGAGAGGCGTGGTGATTACCTGGGGAAAACAGTGCAAGTTGTCCCTCACA TTACTGATGCTGTCCAGNAGTGGGTTATGAATCAAGCCAAGGTGCCGGTGGATGGGTATA ANGGAAGAGCCCAAATATGCGTTATTGAGCTGNGAGGCACCATTGGAGACATCGAAGGAA TGCCGTTTGTGGGAGGCGTTTAGACNATTCCAGTTTAAGGCGAAAGNAGAGAATTCTGTA TATCCAGTTAGCCTTGTCAACAGCTCGTGCTACCGGAGACAAAACCA >OriGene 3' read for NM_019857 unedited
GCGGCTGGGAAAAATCTTCGTTACGNATTTTTAAGTACCAAAGGCTGCCTCTGGNAGGGA AAATAAAACTACCCCTCTGGTTCTGGTTGACAGAAGTATGTATTATCAGATTCCCTGTGA GGCTTTACATCCCATGTTTGCTGGAGAACAGAGGGATTCTCTAAGAGTGTAGTGATTTCT TCAGATAGTTCCTTCATCTTGCCTTCAATTATTTCAGAGGCCTCACAGGCAGTCCCCATT ATTCCCAGGCATGTATTCATTTCAGCTTATTTCCAACTCAGCTATCCTTGGCTCTGAAAA GCTGTCATCACTGGCATCACTGTATCTATCACTGGAAGACAGTTTGCAACCCTGTTGCAA GTACGCATTCAGGTTCCCAGTTGCCTGCAAGTAACAGCCCCAGATCCCGAGGGGAAGGCT TCATCGGCCTCCTATACAACTCACGATGGACCTGGACACCCCAAAATAAGGATGATTCGC CAGTTCCATGATTTCCCTCCTGTCCTCCATCAACATCACTACCTACAAAACTTAAATGAA TTCTCATCACACAGCATAGACTCGCTCCGGCTTTCCCTCCCCCTCACGNCTGCGCCCTCC CTCTCACGCACGGGCCTCCCCCCTCGAACCCTCACTTACCTATTCGNCTGTCCCCTTTTC TCACCCATTAACTGCTCTNNNGCATGTCCCTCTGTTCCCATTCCTAACATCTCCCGCCCT TTTTTTCCGCCTCTGCTCCTGTCTCTCTTATCTTCCTGCGGGCCCTTCGTTACTTACATC CCTTTCCGACCGTCTCTCTCTGTCCCTCGCGCTCACCGCCCCNCTTCACTGCTTATCNAT TTATTCTTATCTTACTTCAANNTCTCCTGTACAGCGTCTGTCACTCTCAGCTATCGTCTA CATCCTCACCCTAATCACAACACAACCCCGTACTTATTGCTGTCTCCTCTCTCCCCCTCT ACAGCCCCACACTCCCGGNCACCCATCCAAGACAACAACCACAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019857 |
| Insert Size | 2440 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019857.3, NP_062831.3 |
| RefSeq Size | 3844 bp |
| RefSeq ORF | 1761 bp |
| Locus ID | 56474 |
| UniProt ID | Q9NRF8 |
| Domains | GATase |
| Protein Pathways | Metabolic pathways, Pyrimidine metabolism |
| Gene Summary | The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Variants 1, 2 and 3 encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205993 | CTPS2 (Myc-DDK-tagged)-Human CTP synthase II (CTPS2), transcript variant 1 |
CNY 3,990.00 |
|
| RC205993L3 | Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205993L4 | Lenti ORF clone of Human CTP synthase II (CTPS2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG205993 | CTPS2 (tGFP-tagged) - Human CTP synthase II (CTPS2), transcript variant 1 |
CNY 4,370.00 |
