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MCM6 (NM_005915) Human Untagged Clone
CAT＃: SC110945
MCM6 (untagged)-Human minichromosome maintenance complex component 6 (MCM6)
CNY 6,024.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MCG40308; Mis5; P105MCM |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110945 sequence for NM_005915 edited (data generated by NextGen Sequencing)
ATGGACCTCGCGGCGGCAGCGGAGCCGGGCGCCGGCAGCCAGCACCTGGAGGTCCGCGAC GAGGTGGCCGAGAAGTGCCAGAAACTGTTCCTGGACTTCTTGGAGGAGTTTCAGAGCAGC GATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGTCCTGAGAGAAACACA TTGGTTGTGAGTTTTGTGGACCTGGAACAATTTAACCAGCAACTTTCCACCACCATTCAA GAGGAGTTCTATAGAGTTTACCCTTACCTGTGTCGGGCCTTGAAAACATTCGTCAAAGAC CGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAAGACCTGCCTACCAGA CACAAGATTCGAGAGCTCACCTCATCCAGAATTGGTTTGCTCACTCGCATCAGTGGGCAG GTGGTGCGGACTCACCCAGTTCACCCAGAGCTTGTGAGCGGAACTTTTCTGTGCTTGGAC TGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACACAGCCAAACATCTGC CGAAATCCAGTTTGTGCCAACAGGAGGAGATTCTTACTGGATACAAATAAATCAAGATTT GTTGATTTTCAAAAGGTTCGTATTCAAGAGACCCAAGCTGAGCTTCCTCGAGGGAGTATC CCCCGCAGTTTAGAAGTAATTTTAAGGGCTGAAGCTGTGGAATCAGCTCAAGCTGGTGAC AAGTGTGACTTTACAGGGACACTGATTGTTGTGCCTGACGTCTCCAAGCTTAGCACACCA GGAGCACGTGCAGAAACTAATTCCCGTGTCAGTGGTGTTGATGGATATGAGACAGAAGGC ATTCGAGGACTCCGGGCCCTTGGTGTTAGGGACCTTTCTTATAGGCTGGTCTTTCTTGCC TGCTGTGTTGCGCCAACCAACCCAAGGTTTGGGGGGAAAGAGCTCAGAGATGAGGAACAG ACAGCTGAGAGCATTAAGAACCAAATGACTGTGAAAGAATGGGAGAAAGTGTTTGAGATG AGTCAAGATAAAAATCTATACCACAATCTTTGTACCAGCCTGTTCCCTACTATACATGGC AATGATGAAGTAAAACGGGGTGTCCTGCTGATGCTCTTTGGTGGCGTTCCAAAGACAACA GGAGAAGGGACCTCTCTTCGAGGGGACATAAATGTTTGCATTGTTGGTGACCCAAGTACA GCTAAGAGCCAATTTCTCAAGCACGTGGAGGAGTTCAGCCCCAGAGCTGTCTACACCAGT GGTAAAGCGTCCAGTGCTGCTGGCTTAACAGCAGCTGTTGTGAGAGATGAAGAATCTCAT GAGTTTGTCATTGAGGCTGGAGCTTTGATGTTGGCTGATAATGGTGTGTGTTGTATTGAT GAATTTGATAAGATGGACGTGCGGGATCAAGTTGCTATTCATGAAGCTATGGAACAGCAG ACCATATCCATCACTAAAGCAGGAGTGAAGGCTACTCTGAACGCCCGGACGTCCATTTTG GCAGCAGCAAACCCAATCAGTGGACACTATGACAGATCAAAATCATTGAAACAGAATATA AATTTGTCAGCTCCCATCATGTCCCGATTCGATCTCTTCTTTATCCTTGTGGATGAATGT AATGAGGTTACAGATTATGCCATTGCCAGGCGCATAGTAGATTTGCATTCAAGAATTGAG GAATCAATTGATCGTGTCTATTCCCTCGATGATATCAGAAGATATCTTCTCTTTGCAAGA CAGTTTAAACCCAAGATTTCCAAAGAGTCAGAGGACTTCATTGTGGAGCAATATAAACAT CTCCGCCAGAGAGATGGTTCTGGAGTGACCAAGTCTTCATGGAGGATTACAGTGCGACAG CTTGAGAGCATGATTCGTCTCTCTGAAGCTATGGCTCGGATGCACTGCTGTGATGAGGTC CAACCTAAACATGTGAAGGAAGCTTTCCGGTTACTGAATAAATCAATCATCCGTGTGGAA ACACCTGATGTCAATCTAGATCAAGAGGAAGAGATCCAGATGGAGGTAGATGAGGGTGCT GGTGGCATCAATGGTCATGCTGACAGCCCTGCTCCTGTGAACGGGATCAATGGCTACAAT GAAGACATAAATCAAGAGTCTGCTCCCAAAGCCTCCTTAAGGCTGGGCTTCTCTGAGTAC TGCCGAATCTCTAACCTTATTGTGCTTCACCTCAGAAAGGTGGAAGAAGAAGAGGACGAG TCAGCATTAAAGAGGAGCGAGCTTGTTAACTGGTACTTGAAGGAAATCGAATCAGAGATA GACTCTGAAGAAGAACTTATAAATAAAAAAAGAATCATAGAGAAAGTTATTCATCGACTC ACACACTATGATCATGTTCTAATTGAGCTCACCCAGGCTGGATTGAAAGGCTCCACAGAG GGAAGTGAGAGCTATGAAGAAGATCCCTACTTGGTAGTTAACCCTAACTACTTGCTCGAA GATTGA Clone variation with respect to NM_005915.4 >OriGene 5' read for NM_005915 unedited
NATTTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGGCGGCGCGCGC AAAGCTGCAGCGTCTGGAAAAAACGACTTGTGGCGGTCGAGCGTGGCGCAGGCGAATCCT CGGCACTAAGCAAATATGGACCTCGCGGCGGCAGCGGAGCCGGGCGCCGGCAGCCAGCAC CTGGAGGTCCGCGACGAGGTGGCCGAGAAGTGCCAGAAACTGTTCCTGGACTTCTTGGAG GAGTTTCAGAGCAGCGATGGAGAAATTAAATACTTGCAATTAGCAGAGGAACTGATTCGT CCTGAGAGAAACACATTGGTTGTGAGTTTTGTGGACCTGGAACAATTTAACCAGCAACTT TCCACCACCATTCAAGAGGAGTTCTATAGAGTTTACCCTTACCTGTGTCGGGCCTTGAAA ACATTCGTCAAAGACCGTAAAGAGATCCCTCTTGCCAAGGATTTTTATGTTGCATTCCAA GACCTGCCTACCAGACACAAGATTCGAGAGCTCACCTCATCCAGAATTGGTTTGCTCACT CGCATCAGTGGGCAGGTGGTGCGGACTCACCCAGTTCACCCAGAGCTTGTGAGCGGAACT TTTCTGTGCTTGGACTGTCAGACAGTGATCAGGGATGTAGAACAGCAGTTCAAATACACA CAGCCAAACATCTGCCGAAATCCAGTTTGTGCCAACAGGAGGAGATTCTTACTGGATACA NNATAATCAAGATTTGTTGATTTTCAAAAGGGTCGTATTCAAGAGACCCCAGCTGAGCTT CCTCGAGGGAGTATCCCCCGCAGTTTAGAAGTAATTTTAGGGCTGAAGCTGTGGAATCAG CTCAAGCTGGTGACCAGTGTGACTTTAAGGGACACCTGATGTTGTGCCTGACGTCTCCAA GCTTACACCACCAGAGCCGTGCAGAAACTAANTCCCTGTCACGGTGGTGATGGAATGAAA CCAAGGCTTCCAGACTCCGCCCCT >OriGene 3' read for NM_005915 unedited
GGACCGCGGCACGCAATCTATAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTAAAAACAAGTTTTTTTATTTTGATAAATAAAAGCAGTACCTGGC ATTGGAAAAAAAGTTTTTTGCTCAATAGGACAGCACATCCCTTAAAAGTAAGGGGCCTTT TTTTACACATGAAAAACAAAGGTTTGGGTTATAAAAACTACACTTTTTTGGGTTCCAACT TCCCTGGGACAGGAAACACCCCAAAGGAAGGGCTGAACCCTGGGTGGGTATAAAACCTGG GATGAATGGGACACATAGGACCTTCAACTCATTTCTTGTTTCTGAAAACAAATCCGGGAA GCATCACTTCCAAAAACATTTCTGCCCCTAAAAAAGCTCCAGCCAGGCTCCAGGCCACGA GGGGCTGGGCCACAGTTCCTCAGCTCTGGCCAGTTACTTTCACTATCTAAATCTTCAAGC AAGTATTTAGGGTTAACTACCAAGTAGGGATCTTCTTCATAGCTCTCACTTCCCTCGGGG GAGCCTTTCAATCCAGCCGGGGGGAGCTCAATTAAAACATGATCATAGGGGGGGAGCCGA TAAATAACTTTCTCTATGATCCTTTTTTTATTAATAAGCTCTTCTTAAAAGTCTATCTCT GATTCGATTTCCTTCAAGCACCAGTTAACAAGCTCGCTCCTCTTTAATGCAGACTTGGCC TCTTCCTTCTACACCCTTTGTGAGGGGAACCACATAAGGTAGAGATTCGGCAGTCCTCAA AAACCCCACCCTTAAGGAGGCTTGGGAGCAAACTCTTGATTTATGTCTTCTTTGAACCAT TGATCCCGTTCCAAGAACAGGGCTGCANCATAACCTTGGTGCCACCAACACCCTATTCAC CTCATTGGGATTTCTTCCTCGGATCTAAATGAAACAGGGGTTCCACCCGTTGAATGATTT TTTAGTACGCGAGCCTCCTCCATGTTAGGGGAACCTATCCAGAAGGCTCCACCATATTTA AG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_005915 |
| Insert Size | 3080 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005915.4, NP_005906.2 |
| RefSeq Size | 3769 bp |
| RefSeq ORF | 2466 bp |
| Locus ID | 4175 |
| UniProt ID | Q14566 |
| Domains | MCM |
| Protein Families | Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Cell cycle, DNA replication |
| Gene Summary | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. [provided by RefSeq, May 2012] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207097 | MCM6 (Myc-DDK-tagged)-Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,016.00 |
|
| RC207097L1 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), Myc-DDK-tagged |
CNY 8,416.00 |
|
| RC207097L2 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), mGFP tagged |
CNY 7,700.00 |
|
| RC207097L3 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC207097L4 | Lenti ORF clone of Human minichromosome maintenance complex component 6 (MCM6), mGFP tagged |
CNY 7,700.00 |
|
| RG207097 | MCM6 (tGFP-tagged) - Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,370.00 |
|
| SC323955 | MCM6 (untagged)-Human minichromosome maintenance complex component 6 (MCM6) |
CNY 6,024.00 |
