LAP2 (TMPO) (AF113682) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	CMD1T; LAP2; LEMD4; PRO0868; TP
Vector	pCMV6-XL6
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF113682, the custom clone sequence may differ by one or more nucleotides ATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTG CAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTA TGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATT TTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATC CCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGA 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AF113682 unedited TACCCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGCAGCAGAAAATACAAGGCAGAATGGAAGTAATGATTCTGACAGATAC AGTGACAATGAAGAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAG GGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGGA GAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAA GCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGC CGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCT AAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCC GTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAA GCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAA TCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTT GAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCA ATAATGTAGTATTTCATTGAAAAGCANACAAAATTATATTAAATGGACTTCATTNAAATG TTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTNGCATATGAATAATCTTNNTTAGCT CTGGAACTTNNTTGTAGCTTTATTTTTTTATGGTGGGCATCTATTTCATTTTTGAAAAAT GTATAGTTNTTTTA
Restriction Sites	NotI-NotI
ACCN	AF113682
Insert Size	2500 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AF113682.1, AAF29583.1
RefSeq Size	1368 bp
RefSeq ORF	1368 bp
Locus ID	7112
Protein Families	Stem cell - Pluripotency, Transmembrane
Gene Summary	Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription. [provided by RefSeq, Aug 2019]

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