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KCTD6 (NM_153331) Human Untagged Clone
CAT＃: SC100338
KCTD6 (untagged)-Human potassium channel tetramerisation domain containing 6 (KCTD6), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | KCASH3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC100338 sequence for NM_153331 edited (data generated by NextGen Sequencing)
ATGGATAATGGAGACTGGGGCTATATGATGACTGACCCAGTCACATTAAATGTAGGTGGA CACTTGTATACAACGTCTCTCACCACATTGACGCGTTACCCGGATTCCATGCTTGGAGCT ATGTTTGGGGGGGACTTCCCCACAGCTCGAGACCCTCAAGGCAATTACTTTATTGATCGA GATGGACCTCTTTTCCGATATGTCCTCAACTTCTTAAGAACTTCAGAATTGACCTTACCG TTGGATTTTAAGGAATTTGATCTGCTTCGGAAAGAAGCAGATTTTTACCAGATTGAGCCC TTGATTCAGTGTCTCAATGATCCTAAGCCTTTGTATCCCATGGATACTTTTGAAGAAGTT GTGGAGCTGTCTAGTACTCGGAAGCTTTCTAAGTACTCCAACCCAGTGGCTGTCATCATA ACGCAACTAACCATCACCACTAAGGTCCATTCCTTACTAGAAGGCATCTCAAATTATTTT ACCAAGTGGAATAAGCACATGATGGACACCAGAGACTGCCAGGTTTCCTTTACTTTTGGA CCCTGTGATTATCACCAGGAAGTTTCTCTTAGGGTCCACCTGATGGAATACATTACAAAA CAAGGTTTCACGATCCGCAACACCCGGGTGCATCACATGAGTGAGCGGGCCAATGAAAAC ACAGTGGAGCACAACTGGACTTTCTGTAGGCTAGCCCGGAAGACAGACGACTGA Clone variation with respect to NM_153331.3 >OriGene 5' read for NM_153331 unedited
TTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCTCCGGCCGCGGGC ATCTCCCGGCCCGGCCGCAGCAGCCGCCGCCGCCGCGCATTTCCCTGAAACCTGGGCTCT TGAAGACGCATCACTGGAGCAGATGGATAATGGAGACTGGGGCTATATGATGACTGACCC AGTCACATTAAATGTAGGTGGACACTTGTATACAACGTCTCTCACCACATTGACGCGTTA CCCGGATTCCATGCTTGGAGCTATGTTTGGGGGGGACTTCCCCACAGCTCGAGACCCTCA AGGCAATTACTTTATTGATCGAGATGGACCTCTTTTCCGATATGTCCTCAACTTCTTAAG AACTTCAGAATTGACCTTACCGTTGGATTTTAAGGAATTTGATCTGCTTCGGAAAGAAGC AGATTTTTACCAGATTGAGCCCTTGATTCAGTGTCTCAATGATCCTAAGCCTTTGTATCC CATGGATACTTTTGAAGAAGTTGTGGAGCTGTCTAGTACTCGGAAGCTTTCTAAGTACTC CAACCCAGTGGCTGTCATCATAACGCAACTAACCATCACCACTAAGGTCCATTCCTTACT AGAAGGCATCTCANATTATTTTACCAAGTGGAATAAGCACATGATGGACACCAGAGACTG CCNAGTTTCCTTTACTTTTGGACCCTGTGATTATCACCAGGAAGTTTCNTCTTAGGGTCC ACCTGATGGAATACATTACAAAACAAGGNTTCACGATCCGCAACACCCGGGTGCATCACA TGAGTGAGCGGGCCAATGAAACACAGTGGAGCACAACTGGACTTTTCTGTAGCTAGCCCG NAAGACGACGACTGATCTNCGACCCTGCCACAGTTCCTGGAAAGACTCTCAGAATGGAAG AACTGATT >OriGene 3' read for NM_153331 unedited
NNAAATTACTTGNACCGCGCCGCATTCTANNGATCGGTTTTTTTTTTTTTTTTTTAATTT TCATATTTCATTTTTTATTAGTTTTGTTTTTTTTTTCTGGTAGACAGTACACTTGGGAAT TATACTGCACCAGGCATAAAGAGTAAGTTTTCTACCACAGGGACATTTTGTATTCAGAAT TCAATATAAATATTTCTAGTCAGACATTTCCATGGCTACAGATATTTGGTTCCTTGATTT ATATGCATAGAAAGAAACAGTTGTCATAACTGTAAAAAGCAGTACTTAATAAGTACTTTT AAATGATTGGAACAGTTTTCCTTTAATATTACAATACTACTTATTTATTGGTTTGGAAAC TAGGTCACCCTACATGATGTTTTGATTTTTCTCAAAGGCATCATGAGTACTCTGCTTATT CTTTCATTCTTGTATTTTTAGCCTTCTAGTTGAGTTAGGGACCATTTTATCAGAAATCAT TTTAGCACTGTAATAAGAAAAGCTCTGTTAAGGGTAGATTATATACCATAATGATTTTCA GACTTCTTTTTATAAAAAAGGTATCTGGAGACTCTGAACAGGCACATGCATACTCAGGGG GAAGGGAACAAAACATGGAGGAGTCTGCCAAAGCACAAAACTTCCTTCTGGTCCTCACTG CCTTCAAATAAATACAACTATTTAAAAGAAAAAAAATATCTCACACTGTGATTTAAAAAA AAAAATCAGTATCTTCCATTTCCTGGAGAGTCTTTCCAGGAACCTGTGGCAGGGTCGGAG ATCAGTCGTCTGTCTTCCGGGCTAGCCTACAGAAAGTCCAGTTGTGCTCCACTGTGTTTT CATTGGCCCGCTCACTCATGTGATGCACCCGGGTGTTGCGGATCGTGAAACCTTGTTTTT GTATGTATTCCATCAGGTGGA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_153331 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_153331.2, NP_699162.2 |
| RefSeq Size | 1823 bp |
| RefSeq ORF | 714 bp |
| Locus ID | 200845 |
| UniProt ID | Q8NC69 |
| Domains | BTB, K_tetra |
| Protein Families | Ion Channels: Other |
| Gene Summary | Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205633 | KCTD6 (Myc-DDK-tagged)-Human potassium channel tetramerisation domain containing 6 (KCTD6), transcript variant 1 |
CNY 2,400.00 |
|
| RC205633L3 | Lenti ORF clone of Human potassium channel tetramerisation domain containing 6 (KCTD6), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205633L4 | Lenti ORF clone of Human potassium channel tetramerisation domain containing 6 (KCTD6), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG205633 | KCTD6 (tGFP-tagged) - Human potassium channel tetramerisation domain containing 6 (KCTD6), transcript variant 1 |
CNY 4,000.00 |
