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EYA4 (NM_001301013) Human Tagged ORF Clone
CAT＃: RG239190
- TrueORF®
EYA4 (tGFP-tagged) - Human EYA transcriptional coactivator and phosphatase 4 (EYA4), transcript variant 6
ORF Plasmid: DDK
"NM_001301013" in other vectors (2)
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CNY 4,940.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Tag | TurboGFP |
| Synonyms | CMD1J; DFNA10 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239190 representing NM_001301013.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGATGTTTCACAA TCTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGAT ACTCCAGGTAGCTCCAAACTGGAAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGA GGGGAAAACATGACTGTTTTAAACACAGCAGACTGGTTGCTGAGTTGCAACACCCCCTCTTCTGCAACA ATGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGATGGA GCGCTTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTAT TCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCT GCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACA GGACAGCCCTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGA CTTTCCCAAACTCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAG CCAGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTATTTATGCA AATAATTCAGTTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTT GGCCAAAACCAGTATGCACAGTATTATTCAGCATCAACGTATGGAGCGTATATGACATCGAATAACACA GCCGATGGCACACCCTCTTCAACCTCTACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACTAACCAA CCAGGTACAGATCTTCACCCAGGAGAGTTCGATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTT GATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTCCAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCG CCTCCTGATAGTGACCTGGAGCGTGTGTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCA CTGCTCACCGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGC ATGGAAGAAATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGGAGTGTGATCAA GTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTTTGCAACTGAT GGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGTAAGAGGAGGGGTTGACTGG ATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGAATTATATAACACCTACAAGAACAACGTTGGA GGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAGTTAAGGGCAGAGATTGAAGGTCTGACAGAT TCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTG GTAACGACAACTCAACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCC ATTGAGAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGTTGCTTTGAACGAATAATGCAAAGGTTT GGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGAACAGGCAGCAAAAAAGCACAAC ATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCTCCACCAAGCACTGGAATTAGAGTAT TTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239190
Blue=ORF Red=Cloning site Green=Tag(s) MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG GENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQY SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESG LSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAF GQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGTDLHPGEFDTMQSPSTPIKDL DERTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLR MEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDW MRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVL VTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHN MPFWRISSHSDLLALHQALELEYL TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001301013 |
| ORF Size | 1935 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001301013.1, NP_001287942.1 |
| RefSeq Size | 5573 bp |
| RefSeq ORF | 1938 bp |
| Locus ID | 2070 |
| UniProt ID | O95677 |
| Protein Families | Druggable Genome, Phosphatase, Transcription Factors |
| MW | 70.6 kDa |
| Gene Summary | This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] |
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