Folylpolyglutamate synthase (FPGS) (NM_001288803) Human Tagged ORF Clone
CAT#: RG238901
- TrueORF®
FPGS (tGFP-tagged) - Human folylpolyglutamate synthase (FPGS), transcript variant 3
ORF Plasmid: DDK
"NM_001288803" in other vectors (2)
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CNY 4,940.00
Specifications
Product Data | |
Tag | TurboGFP |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001288803 |
ORF Size | 1683 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001288803.1, NP_001275732.1 |
RefSeq Size | 2230 bp |
RefSeq ORF | 1686 bp |
Locus ID | 2356 |
UniProt ID | Q05932 |
Protein Pathways | Folate biosynthesis, Metabolic pathways |
MW | 62 kDa |
Gene Summary | This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014] |
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