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MAGI3 (NM_152900) Human Tagged ORF Clone
CAT＃: RG218925
- TrueORF®
MAGI3 (tGFP-tagged) - Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2
ORF Plasmid: DDK
"NM_152900" in other vectors (6)
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CNY 12,350.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | dJ730K3.2; MAGI-3 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG218925 representing NM_152900
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGAAGACGCTGAAGAAGAAGAGGCACTGGCTCAGCAAGGTGCAGGAGTGCGCCGTGTCCTGGGCCG GGCCCCCGGGAGACTTCGGCGCGGAGATCCGCGGTGGCGCGGAGCGTGGCGAGTTCCCCTACCTGGGGCG GCTCCGCGAGGAGCCCGGCGGGGGCACCTGCTGCGTCGTCTCGGGCAAGGCGCCCAGCCCAGGCGATGTG CTGCTGGAGGTAAACGGGACGCCTGTCAGCGGGCTCACCAACCGGGACACCCTGGCTGTCATCCGCCACT TCCGCGAGCCCATCCGTCTCAAGACTGTGAAACCAGGCAAAGTCATTAATAAAGATTTGCGGCATTACCT AAGTCTTCAGTTTCAAAAAGGATCAATTGACCACAAACTGCAGCAAGTGATCAGAGATAATCTCTACTTG AGAACCATTCCATGCACTACAAGGGCCCCCAGGGATGGAGAAGTACCAGGAGTGGATTATAATTTCATTT CCGTTGAACAGTTCAAAGCACTGGAAGAGAGTGGAGCATTGTTAGAAAGTGGGACATATGATGGAAACTT CTATGGAACTCCCAAGCCTCCAGCAGAACCCAGCCCTTTTCAGCCAGATCCAGTTGATCAAGTCCTCTTT GATAATGAGTTTGATGCAGAATCTCAAAGAAAACGAACGACATCTGTCAGCAAGATGGAAAGAATGGATA GCTCTCTTCCTGAAGAGGAAGAAGATGAGGACAAGGAAGCTATTAATGGCAGTGGAAACGCAGAAAACGG AGAGAGGCATTCTGAGTCATCTGACTGGATGAAGACTGTTCCAAGTTACAACCAAACAAATAGCTCCATG GACTTTAGAAATTATATGATGAGAGATGAGACTCTGGAACCACTGCCCAAAAACTGGGAAATGGCCTACA CTGACACAGGGATGATCTACTTCATTGACCACAATACCAAGACAACCACCTGGTTGGATCCTCGTCTTTG TAAGAAAGCCAAAGCCCCTGAAGACTGTGAAGATGGAGAGCTTCCTTATGGCTGGGAGAAAATAGAGGAC CCTCAGTATGGGACATACTATGTTGATCACCTTAACCAGAAAACCCAGTTTGAAAATCCAGTGGAGGAAG CCAAAAGGAAAAAGCAGTTAGGACAGGTTGAAATTGGGTCTTCAAAACCAGATATGGAAAAATCACACTT CACAAGAGATCCATCCCAGCTTAAAGGTGTCCTTGTTCGAGCATCACTGAAAAAAAGCACAATGGGATTT GGTTTTACTATTATTGGTGGAGATAGACCTGATGAGTTCCTACAAGTGAAAAATGTGCTGAAAGATGGTC CCGCAGCTCAGGATGGGAAAATTGCACCAGGCGATGTTATTGTAGACATCAATGGCAACTGTGTCCTCGG TCACACTCATGCAGATGTTGTCCAGATGTTTCAATTGGTACCTGTCAATCAGTATGTAAACCTCACTTTA TGTCGTGGTTATCCACTTCCTGATGACAGTGAAGATCCTGTTGTGGACATTGTTGCTGCTACCCCTGTCA TCAATGGACAGTCATTAACCAAGGGAGAGACTTGCATGAATCCTCAGGATTTTAAGCCAGGAGCAATGGT TCTGGAGCAGAATGGAAAATCGGGACACACTTTGACTGGTGATGGTCTCAATGGACCATCAGATGCAAGT GAGCAGAGAGTATCCATGGCATCGTCAGGCAGCTCCCAGCCTGAACTAGTGACTATCCCTTTGATTAAGG GCCCTAAAGGGTTTGGGTTTGCAATTGCTGACAGCCCTACTGGACAGAAGGTGAAAATGATACTGGATAG TCAGTGGTGTCAAGGCCTTCAGAAAGGAGATATAATTAAGGAAATATACCATCAAAATGTGCAGAATTTA ACACATCTCCAAGTGGTAGAGGTGCTAAAGCAGTTTCCAGTAGGTGCTGATGTACCATTGCTTATCTTAA GAGGAGGTCCTCCTTCACCAACCAAAACTGCCAAAATGAAAACAGATAAAAAGGAAAATGCAGGAAGTTT GGAGGCCATAAATGAGCCTATTCCTCAGCCTATGCCTTTTCCACCGAGCATTATCAGGTCAGGATCCCCA AAATTGGATCCTTCTGAGGTCTACCTGAAATCTAAGACTTTATATGAAGATAAACCACCAAACACCAAAG ATTTGGATGTTTTTCTTCGAAAACAAGAGTCAGGGTTTGGCTTCAGGGTGCTAGGAGGAGATGGACCTGA CCAGTCTATATATATTGGGGCTATTATTCCCCTGGGAGCAGCTGAGAAAGATGGTCGGCTCCGCGCAGCT GATGAACTAATGTGCGTTGATGGAATTCCTGTTAAAGGGAAATCACACAAACAAGTCTTGGACCTCATGA CAACTGCTGCTCCAAATGGCCATGTGTTACTAACTGTCAGACGGAAGATCTTCTATGGAGAAAAACAACC CGAGGACGACAGCTCTCAGGCCTTCATTTCAACACAGAATGGATCTCCCCGCCTGAACCGGGCAGAGGTC CCAGCCAGGCCTGCACCCCAGGAGCCCTATGATGTTGTCTTGCAACGAAAAGAAAATGAAGGATTTGGCT TTGTCATCCTCACCTCCAAAAACAAACCACCTCCAGGAGTTATTCCTCATAAAATTGGCCGAGTCATAGA AGGAAGTCCGGCTGACCGCTGTGGAAAACTGAAAGTTGGAGATCATATCTCTGCAGTGAATGGGCAGTCC ATTGTTGAACTGTCTCATGATAACATTGTTCAGCTGATCAAAGATGCTGGTGTCACCGTCACACTAACGG TCATTGCTGAAGAAGAGCATCATGGTCCACCATCAGGAACAAACTCAGCCAGGCAAAGCCCAGCCCTGCA GCACAGGCCCATGGGACAGTCACAGGCCAACCACATACCTGGGGACAGAAGTGCCCTAGAAGGTGAAATT GGAAAAGATGTCTCCACTTCTTACAGACATTCTTGGCCAGACCACAAGCACCTTGCACAGCCTGACACCG CAGTAATTTCAGTTGTAGGCAGTCGGCACAATCAGAACCTTGGTTGTTATCCAGTAGAGCTGGAGAGAGG CCCCCGGGGCTTTGGATTCAGCCTCCGAGGGGGGAAGGAGTACAACATGGGGCTGTTCATCCTTCGTCTT GCTGAAGATGGTCCTGCCATCAAAGATGGCAGAATTCATGTTGGTGACCAGATTGTTGAAATCAATGGGG AACCTACACAAGGAATCACACATACTCGAGCAATTGAGCTCATTCAGGCTGGTGGAAATAAAGTTCTTCT TCTTTTGAGGCCAGGAACTGGCTTGATACCTGACCATGGTTTGGCTCCTTCCGGTCTGTGCTCCTACGTG AAACCCGAGCAACAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG218925 representing NM_152900
Red=Cloning site Green=Tags(s) MSKTLKKKRHWLSKVQECAVSWAGPPGDFGAEIRGGAERGEFPYLGRLREEPGGGTCCVVSGKAPSPGDV LLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYL RTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGTPKPPAEPSPFQPDPVDQVLF DNEFDAESQRKRTTSVSKMERMDSSLPEEEEDEDKEAINGSGNAENGERHSESSDWMKTVPSYNQTNSSM DFRNYMMRDETLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIED PQYGTYYVDHLNQKTQFENPVEEAKRKKQLGQVEIGSSKPDMEKSHFTRDPSQLKGVLVRASLKKSTMGF GFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTL CRGYPLPDDSEDPVVDIVAATPVINGQSLTKGETCMNPQDFKPGAMVLEQNGKSGHTLTGDGLNGPSDAS EQRVSMASSGSSQPELVTIPLIKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNL THLQVVEVLKQFPVGADVPLLILRGGPPSPTKTAKMKTDKKENAGSLEAINEPIPQPMPFPPSIIRSGSP KLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAA DELMCVDGIPVKGKSHKQVLDLMTTAAPNGHVLLTVRRKIFYGEKQPEDDSSQAFISTQNGSPRLNRAEV PARPAPQEPYDVVLQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKVGDHISAVNGQS IVELSHDNIVQLIKDAGVTVTLTVIAEEEHHGPPSGTNSARQSPALQHRPMGQSQANHIPGDRSALEGEI GKDVSTSYRHSWPDHKHLAQPDTAVISVVGSRHNQNLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRL AEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGLAPSGLCSYV KPEQH TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_152900 |
| ORF Size | 3375 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152900.1, NP_690864.1 |
| RefSeq Size | 3504 bp |
| RefSeq ORF | 3378 bp |
| Locus ID | 260425 |
| UniProt ID | Q5TCQ9 |
| Protein Families | Druggable Genome |
| Protein Pathways | Tight junction |
| Gene Summary | Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218925 | MAGI3 (Myc-DDK-tagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2 |
CNY 7,832.00 |
|
| RC218925L1 | Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, Myc-DDK-tagged |
CNY 10,232.00 |
|
| RC218925L2 | Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, mGFP tagged |
CNY 13,110.00 |
|
| RC218925L3 | Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, Myc-DDK-tagged |
CNY 13,110.00 |
|
| RC218925L4 | Lenti ORF clone of Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2, mGFP tagged |
CNY 13,110.00 |
|
| SC306520 | MAGI3 (untagged)-Human membrane associated guanylate kinase, WW and PDZ domain containing 3 (MAGI3), transcript variant 2 |
CNY 7,840.00 |
