United States
Germany
Japan
United Kingdom
China
OSMR (NM_003999) Human Tagged ORF Clone
CAT＃: RG216943
- TrueORF®
OSMR (tGFP-tagged) - Human oncostatin M receptor (OSMR), transcript variant 1
ORF Plasmid: DDK
"NM_003999" in other vectors (6)
Need custom modification / cloning service?
Get a free quote
CNY 12,352.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | IL-31R-beta; IL-31RB; OSMRB; OSMRbeta; PLCA1 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG216943 representing NM_003999
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTCTATTTGCAGTCTTTCAGACAACATTCTTCTTAACATTGCTGTCCTTGAGGACTTACCAGAGTG AAGTCTTGGCTGAACGTTTACCATTGACTCCTGTATCACTTAAAGTTTCCACCAATTCTACGCGTCAGAG TTTGCACTTACAATGGACTGTCCACAACCTTCCTTATCATCAGGAATTGAAAATGGTATTTCAGATCCAG ATCAGTAGGATTGAAACATCCAATGTCATCTGGGTGGGGAATTACAGCACCACTGTGAAGTGGAACCAGG TTCTGCATTGGAGCTGGGAATCTGAGCTCCCTTTGGAATGTGCCACACACTTTGTAAGAATAAAGAGTTT GGTGGACGATGCCAAGTTCCCTGAGCCAAATTTCTGGAGCAACTGGAGTTCCTGGGAGGAAGTCAGTGTA CAAGATTCTACTGGACAGGATATATTGTTCGTTTTCCCTAAAGATAAGCTGGTGGAAGAAGGCACCAATG TTACCATTTGTTACGTTTCTAGGAACATTCAAAATAATGTATCCTGTTATTTGGAAGGGAAACAGATTCA TGGAGAACAACTTGATCCACATGTAACTGCATTCAACTTGAATAGTGTGCCTTTCATTAGGAATAAAGGG ACAAATATCTATTGTGAGGCAAGTCAAGGAAATGTCAGTGAAGGCATGAAAGGCATCGTTCTTTTTGTCT CAAAAGTACTTGAGGAGCCCAAGGACTTTTCTTGTGAAACCGAGGACTTCAAGACTTTGCACTGTACTTG GGATCCTGGGACGGACACTGCCTTGGGGTGGTCTAAACAACCTTCCCAAAGCTACACTTTATTTGAATCA TTTTCTGGGGAAAAGAAACTTTGTACACACAAAAACTGGTGTAATTGGCAAATAACTCAAGACTCACAAG AAACCTATAACTTCACACTCATAGCTGAAAATTACTTAAGGAAGAGAAGTGTCAATATCCTTTTTAACCT GACTCATCGAGTTTATTTAATGAATCCTTTTAGTGTCAACTTTGAAAATGTAAATGCCACAAATGCCATC ATGACCTGGAAGGTGCACTCCATAAGGAATAATTTCACATATTTGTGTCAGATTGAACTCCATGGTGAAG GAAAAATGATGCAATACAATGTTTCCATCAAGGTGAACGGTGAGTACTTCTTAAGTGAACTGGAACCTGC CACAGAGTACATGGCGCGAGTACGGTGTGCTGATGCCAGCCACTTCTGGAAATGGAGTGAATGGAGTGGT CAGAACTTCACCACACTTGAAGCTGCTCCCTCAGAGGCCCCTGATGTCTGGAGAATTGTGAGCTTGGAGC CAGGAAATCATACTGTGACCTTATTCTGGAAGCCATTATCAAAACTGCATGCCAATGGAAAGATCCTGTT CTATAATGTAGTTGTAGAAAACCTAGACAAACCATCCAGTTCAGAGCTCCATTCCATTCCAGCACCAGCC AACAGCACAAAACTAATCCTTGACAGGTGTTCCTACCAAATCTGCGTCATAGCCAACAACAGTGTGGGTG CTTCTCCTGCTTCTGTAATAGTCATCTCTGCAGACCCCGAAAACAAAGAGGTTGAGGAAGAAAGAATTGC AGGCACAGAGGGTGGATTCTCTCTGTCTTGGAAACCCCAACCTGGAGATGTTATAGGCTATGTTGTGGAC TGGTGTGACCATACCCAGGATGTGCTCGGTGATTTCCAGTGGAAGAATGTAGGTCCCAATACCACAAGCA CAGTCATTAGCACAGATGCTTTTAGGCCAGGAGTTCGATATGACTTCAGAATTTATGGGTTATCTACAAA AAGGATTGCTTGTTTATTAGAGAAAAAAACAGGATACTCTCAGGAACTTGCTCCTTCAGACAACCCTCAC GTGCTGGTGGATACATTGACATCCCACTCCTTCACTCTGAGTTGGAAAGATTACTCTACTGAATCTCAAC CTGGTTTTATACAAGGGTACCATGTCTATCTGAAATCCAAGGCGAGGCAGTGCCACCCACGATTTGAAAA GGCAGTTCTTTCAGATGGTTCAGAATGTTGCAAATACAAAATTGACAACCCGGAAGAAAAGGCATTGATT GTGGACAACCTAAAGCCAGAATCCTTCTATGAGTTTTTCATCACTCCATTCACTAGTGCTGGTGAAGGCC CCAGTGCTACGTTCACGAAGGTCACGACTCCGGATGAACACTCCTCGATGCTGATTCATATCCTACTGCC CATGGTTTTCTGCGTCTTGCTCATCATGGTCATGTGCTACTTGAAAAGTCAGTGGATCAAGGAGACCTGT TATCCTGACATCCCTGACCCTTACAAGAGCAGCATCCTGTCATTAATAAAATTCAAGGAGAACCCTCACC TAATAATAATGAATGTCAGTGACTGTATCCCAGATGCTATTGAAGTTGTAAGCAAGCCAGAAGGGACAAA GATACAGTTCCTAGGCACTAGGAAGTCACTCACAGAAACCGAGTTGACTAAGCCTAACTACCTTTATCTC CTTCCAACAGAAAAGAATCACTCTGGCCCTGGCCCCTGCATCTGTTTTGAGAACTTGACCTATAACCAGG CAGCTTCTGACTCTGGCTCTTGTGGCCATGTTCCAGTATCCCCAAAAGCCCCAAGTATGCTGGGACTAAT GACCTCACCTGAAAATGTACTAAAGGCACTAGAAAAAAACTACATGAACTCCCTGGGAGAAATCCCAGCT GGAGAAACAAGTTTGAATTATGTGTCCCAGTTGGCTTCACCCATGTTTGGAGACAAGGACAGTCTCCCAA CAAACCCAGTAGAGGCACCACACTGTTCAGAGTATAAAATGCAAATGGCAGTCTCCCTGCGTCTTGCCTT GCCTCCCCCGACCGAGAATAGCAGCCTCTCCTCAATTACCCTTTTAGATCCAGGTGAACACTACTGC AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG216943 representing NM_003999
Red=Cloning site Green=Tags(s) MALFAVFQTTFFLTLLSLRTYQSEVLAERLPLTPVSLKVSTNSTRQSLHLQWTVHNLPYHQELKMVFQIQ ISRIETSNVIWVGNYSTTVKWNQVLHWSWESELPLECATHFVRIKSLVDDAKFPEPNFWSNWSSWEEVSV QDSTGQDILFVFPKDKLVEEGTNVTICYVSRNIQNNVSCYLEGKQIHGEQLDPHVTAFNLNSVPFIRNKG TNIYCEASQGNVSEGMKGIVLFVSKVLEEPKDFSCETEDFKTLHCTWDPGTDTALGWSKQPSQSYTLFES FSGEKKLCTHKNWCNWQITQDSQETYNFTLIAENYLRKRSVNILFNLTHRVYLMNPFSVNFENVNATNAI MTWKVHSIRNNFTYLCQIELHGEGKMMQYNVSIKVNGEYFLSELEPATEYMARVRCADASHFWKWSEWSG QNFTTLEAAPSEAPDVWRIVSLEPGNHTVTLFWKPLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPA NSTKLILDRCSYQICVIANNSVGASPASVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVD WCDHTQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELAPSDNPH VLVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDGSECCKYKIDNPEEKALI VDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIHILLPMVFCVLLIMVMCYLKSQWIKETC YPDIPDPYKSSILSLIKFKENPHLIIMNVSDCIPDAIEVVSKPEGTKIQFLGTRKSLTETELTKPNYLYL LPTEKNHSGPGPCICFENLTYNQAASDSGSCGHVPVSPKAPSMLGLMTSPENVLKALEKNYMNSLGEIPA GETSLNYVSQLASPMFGDKDSLPTNPVEAPHCSEYKMQMAVSLRLALPPPTENSSLSSITLLDPGEHYC SGPTRTRRLE - GFP Tag - V |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_003999 |
| ORF Size | 2937 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003999.3 |
| RefSeq Size | 4171 bp |
| RefSeq ORF | 2940 bp |
| Locus ID | 9180 |
| UniProt ID | Q99650 |
| Domains | FN3 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
| Gene Summary | This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation
,Sharanek, A;Burban, A;Laaper, M;Heckel, E;Joyal, JS;Soleimani, VD;Jahani-Asl, A;,
Nat Commun
,PubMed ID 32807793
[OSMR]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216943 | OSMR (Myc-DDK-tagged)-Human oncostatin M receptor (OSMR), transcript variant 1 |
CNY 10,752.00 |
|
| RC216943L1 | Lenti ORF clone of Human oncostatin M receptor (OSMR), transcript variant 1, Myc-DDK-tagged |
CNY 13,152.00 |
|
| RC216943L2 | Lenti ORF clone of Human oncostatin M receptor (OSMR), transcript variant 1, mGFP tagged |
CNY 11,690.00 |
|
| RC216943L3 | Lenti ORF clone of Human oncostatin M receptor (OSMR), transcript variant 1, Myc-DDK-tagged |
CNY 11,690.00 |
|
| RC216943L4 | Lenti ORF clone of Human oncostatin M receptor (OSMR), transcript variant 1, mGFP tagged |
CNY 11,690.00 |
|
| SC315027 | OSMR (untagged)-Human oncostatin M receptor (OSMR), transcript variant 1 |
CNY 7,176.00 |
