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ABCA2 (NM_001606) Human Tagged ORF Clone
CAT＃: RG216059
- TrueORF®
ABCA2 (tGFP-tagged) - Human ATP-binding cassette, sub-family A (ABC1), member 2 (ABCA2), transcript variant 1
ORF Plasmid: DDK
"NM_001606" in other vectors (2)
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CNY 20,900.00
货期*
3周
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ABC2; IDPOGSA |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG216059 representing NM_001606
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCTTCCTGCACCAGCTGCAGCTGCTGCTCTGGAAGAACGTGACGCTCAAACGCCGGAGCCCGTGGG TCCTGGCCTTCGAGATCTTCATCCCCCTGGTGCTGTTCTTTATCCTGCTGGGGCTGCGACAGAAGAAGCC CACCATCTCCGTGAAGGAAGTCTCCTTCTACACAGCGGCGCCCCTGACGTCTGCCGGCATCCTGCCTGTC ATGCAATCGCTGTGCCCGGACGGCCAGCGAGACGAGTTCGGCTTCCTGCAGTACGCCAACTCCACGGTCA CGCAGCTGCTTGAGCGCCTGGACCGCGTGGTGGAGGAAGGCAACCTGTTTGACCCAGCGCGGCCCAGCCT GGGCTCAGAGCTCGAGGCCCTACGCCAGCATCTGGAGGCCCTCAGTGCGGGCCCGGGCACCTCGGGGAGC CACCTGGACAGATCCACAGTGTCTTCCTTCTCTCTGGACTCGGTGGCCAGAAACCCGCAGGAGCTCTGGC GTTTCCTGACGCAAAACTTGTCGCTGCCCAATAGCACGGCCCAAGCACTCTTGGCCGCCCGTGTGGACCC GCCCGAGGTCTACCACCTGCTCTTTGGTCCCTCATCTGCCCTGGATTCACAGTCTGGCCTCCACAAGGGT CAGGAGCCCTGGAGCCGCCTAGGGGGCAATCCCCTGTTCCGGATGGAGGAGCTGCTGCTGGCTCCTGCCC TCCTGGAGCAGCTCACCTGCACGCCGGGCTCGGGGGAGCTGGGCCGGATCCTCACTGTGCCTGAGAGTCA GAAGGGAGCCCTGCAGGGCTACCGGGATGCTGTCTGCAGTGGGCAGGCTGCTGCGCGTGCCAGGCGCTTC TCTGGGCTGTCTGCTGAGCTCCGGAACCAGCTGGACGTGGCCAAGGTCTCCCAGCAGCTGGGCCTGGATG CCCCCAACGGCTCGGACTCCTCGCCACAGGCGCCACCCCCACGGAGGCTGCAGGCGCTTCTGGGGGACCT GCTGGATGCCCAGAAGGTTCTGCAGGATGTGGATGTCCTGTCGGCCCTGGCCCTGCTACTGCCCCAGGGT GCCTGCACTGGCCGGACCCCCGGACCCCCAGCCAGTGGTGCGGGTGGGGCGGCCAATGGCACTGGGGCAG GGGCAGTCATGGGCCCCAACGCCACCGCTGAGGAGGGCGCACCCTCTGCTGCAGCACTGGCCACCCCGGA CACGCTGCAGGGCCAGTGCTCAGCCTTCGTACAGCTCTGGGCCGGCCTGCAGCCCATCTTGTGTGGCAAC AACCGCACCATTGAACCCGAGGCGCTGCGGCGGGGCAACATGAGCTCCCTGGGCTTCACGAGCAAGGAGC AGCGGAACCTGGGCCTCCTCGTGCACCTCATGACCAGCAACCCCAAAATCCTGTACGCGCCTGCGGGCTC TGAGGTCGACCGCGTCATCCTCAAGGCCAACGAGACTTTTGCTTTTGTGGGCAACGTGACTCACTATGCC CAGGTCTGGCTCAACATCTCGGCGGAGATCCGCAGCTTCCTGGAGCAGGGCAGGCTGCAGCAACACCTGC GCTGGCTGCAGCAGTATGTAGCAGAGCTGCGGCTGCACCCCGAGGCACTGAACCTGTCACTGGATGAGCT GCCGCCGGCCCTGAGACAGGACAACTTCTCGCTGCCCAGTGGCATGGCCCTCCTGCAGCAGCTGGATACC ATTGACAACGCGGCCTGCGGCTGGATCCAGTTCATGTCCAAGGTGAGCGTGGACATCTTCAAGGGCTTCC CCGACGAGGAGAGCATTGTCAACTACACCCTCAACCAGGCCTACCAGGACAACGTCACTGTTTTTGCCAG TGTGATCTTCCAGACCCGGAAGGACGGCTCGCTCCCGCCTCACGTGCACTACAAGATCCGCCAGAACTCC AGCTTCACCGAGAAAACCAACGAGATCCGCCGCGCCTACTGGCGGCCTGGGCCCAATACTGGCGGCCGCT TCTACTTCCTCTACGGCTTCGTCTGGATCCAGGACATGATGGAGCGCGCCATCATCGACACTTTTGTGGG GCACGATGTGGTGGAGCCAGGCAGCTACGTGCAGATGTTCCCCTACCCCTGCTACACACGCGATGACTTC CTGTTTGTCATTGAGCACATGATGCCGCTGTGCATGGTGATCTCCTGGGTCTACTCCGTGGCCATGACCA TCCAGCACATCGTGGCGGAGAAGGAGCACCGGCTCAAGGAGGTGATGAAGACCATGGGCCTGAACAACGC GGTGCACTGGGTGGCCTGGTTCATCACCGGCTTTGTGCAGCTGTCCATCTCCGTGACAGCACTCACCGCC ATCCTGAAGTACGGCCAGGTGCTTATGCACAGCCACGTGGTCATCATCTGGCTCTTCCTGGCAGTCTACG CGGTGGCCACCATCATGTTCTGCTTCCTGGTGTCTGTGCTGTACTCCAAGGCCAAGCTGGCCTCGGCCTG CGGTGGCATCATCTACTTCCTGAGCTACGTGCCCTACATGTACGTGGCGATCCGAGAGGAGGTGGCGCAT GATAAGATCACGGCCTTCGAGAAGTGCATCGCGTCCCTCATGTCCACGACGGCCTTTGGTCTGGGCTCTA AGTACTTCGCGCTGTATGAGGTGGCCGGCGTGGGCATCCAGTGGCACACCTTCAGCCAGTCCCCGGTGGA GGGGGACGACTTCAACTTGCTCCTGGCTGTCACCATGCTGATGGTGGACGCCGTGGTCTATGGCATCCTC ACGTGGTACATTGAGGCTGTGCACCCAGGCATGTACGGGCTGCCCCGGCCCTGGTACTTCCCACTGCAGA AGTCCTACTGGCTGGGCAGTGGGCGGACAGAAGCCTGGGAGTGGAGCTGGCCGTGGGCACGCACCCCCCG CCTCAGTGTCATGGAGGAGGACCAGGCCTGTGCCATGGAGAGCCGGCGCTTTGAGGAGACCCGTGGCATG GAGGAGGAGCCCACCCACCTGCCTCTGGTTGTCTGCGTGGACAAACTCACCAAGGTCTACAAGGACGACA AGAAGCTGGCCCTGAACAAGCTGAGCCTGAACCTCTACGAGAACCAGGTGGTCTCCTTCTTGGGCCACAA CGGGGCGGGCAAGACCACCACCATGTCCATCCTGACCGGCCTGTTCCCTCCAACGTCGGGTTCCGCCACC ATCTACGGGCACGACATCCGCACGGAGATGGATGAGATCCGCAAGAACCTGGGCATGTGCCCGCAGCACA ATGTGCTCTTTGACCGGCTCACGGTGGAGGAACACCTCTGGTTCTACTCACGGCTCAAGAGCATGGCTCA GGAGGAGATCCGCAGAGAGATGGACAAGATGATCGAGGACCTGGAGCTCTCCAACAAACGGCACTCACTG GTGCAGACATTGTCGGGTGGCATGAAGCGCAAGCTGTCCGTGGCCATCGCCTTCGTGGGCGGCTCTCGCG CCATCATCCTGGACGAGCCCACGGCGGGCGTGGACCCCTACGCGCGCCGCGCCATCTGGGACCTCATCCT GAAGTACAAGCCAGGCCGCACCATCCTTCTGTCCACCCACCACATGGATGAGGCTGACCTGCTTGGGGAC CGCATTGCCATCATCTCCCATGGGAAGCTCAAGTGCTGCGGCTCCCCGCTCTTCCTCAAGGGCACCTATG GCGACGGGTACCGCCTCACGCTGGTCAAGCGGCCCGCCGAGCCGGGGGGCCCCCAAGAGCCAGGGCTGGC ATCCAGCCCCCCAGGTCGGGCCCCGCTGAGCAGCTGCTCCGAGCTCCAGGTGTCCCAGTTCATCCGCAAG CATGTGGCCTCCTGCCTGCTGGTCTCAGACACAAGCACGGAGCTCTCCTACATCCTGCCCAGCGAGGCCG CCAAGAAGGGGGCTTTCGAGCGCCTCTTCCAGCACCTGGAGCGCAGCCTGGATGCACTGCACCTCAGCAG CTTCGGGCTGATGGACACGACCCTGGAGGAAGTGTTCCTCAAGGTGTCGGAGGAGGATCAGTCGCTGGAG AACAGTGAGGCCGATGTGAAGGAGTCCAGGAAGGATGTGCTCCCTGGGGCGGAGGGCCCGGCGTCTGGGG AGGGTCACGCTGGCAATCTGGCCCGGTGCTCGGAGCTGACCCAGTCGCAGGCATCGCTGCAGTCGGCGTC ATCTGTGGGCTCTGCCCGTGGCGACGAGGGAGCTGGCTACACCGACGTCTATGGCGACTACCGCCCCCTC TTTGATAACCCACAGGACCCAGACAATGTCAGCCTGCAAGAGGTGGAGGCAGAGGCCCTGTCGAGGGTCG GCCAGGGCAGCCGCAAGCTGGACGGCGGGTGGCTGAAGGTGCGCCAGTTCCACGGGCTGCTGGTCAAACG CTTCCACTGCGCCCGCCGCAACTCCAAGGCACTCTTCTCCCAGATCTTGCTGCCAGCCTTCTTCGTCTGC GTGGCCATGACCGTGGCCCTGTCCGTCCCGGAGATTGGTGATCTGCCCCCGCTGGTCCTGTCACCTTCCC AGTACCACAACTACACCCAGCCCCGTGGCAATTTCATCCCCTACGCCAACGAGGAGCGCCGCGAGTACCG GCTGCGGCTATCGCCCGACGCCAGCCCCCAGCAGCTCGTGAGCACGTTCCGGCTGCCGTCGGGGGTGGGT GCCACCTGCGTGCTCAAGTCTCCCGCCAACGGCTCGCTGGGGCCCACGTTGAACCTGAGCAGCGGGGAGT CGCGCCTGCTGGCGGCTCGGTTCTTCGACAGCATGTGTCTGGAGTCCTTCACACAGGGGCTGCCACTGTC CAATTTCGTGCCACCCCCACCCTCGCCCGCCCCATCTGACTCGCCAGCGTCCCCGGATGAGGACCTGCAG GCCTGGAACGTCTCCCTGCCGCCCACCGCTGGGCCAGAAATGTGGACGTCGGCACCCTCCCTGCCGCGCC TGGTACGGGAGCCCGTCCGCTGCACCTGCTCTGCGCAGGGCACCGGCTTCTCCTGCCCCAGCAGTGTGGG CGGGCACCCGCCCCAGATGCGGGTGGTCACAGGCGACATCCTGACCGACATCACCGGCCACAATGTCTCT GAGTACCTGCTCTTCACCTCCGACCGCTTCCGACTGCACCGGTATGGGGCCATCACCTTTGGAAACGTCC TGAAGTCCATCCCAGCCTCATTTGGCACCAGGGCCCCACCCATGGTGCGGAAGATCGCGGTGCGCAGGGC TGCCCAGGTTTTCTACAACAACAAGGGCTATCACAGCATGCCCACCTACCTCAACAGCCTCAACAACGCC ATCCTGCGTGCCAACCTGCCCAAGAGCAAGGGCAACCCGGCGGCTTACGGCATCACCGTCACCAACCACC CCATGAATAAGACCAGCGCCAGCCTCTCCCTGGATTACCTGCTGCAGGGCACGGATGTCGTCATCGCCAT CTTCATCATCGTGGCCATGTCCTTCGTGCCGGCCAGCTTCGTTGTCTTCCTCGTGGCCGAGAAGTCCACC AAGGCCAAGCACCTGCAGTTTGTCAGCGGCTGCAACCCCATCATCTACTGGCTGGCGAACTACGTGTGGG ACATGCTCAACTACCTGGTCCCCGCTACCTGCTGTGTCATCATCCTGTTTGTGTTCGACCTGCCGGCCTA CACGTCGCCCACCAACTTCCCTGCCGTCCTCTCCCTCTTCCTGCTCTATGGGTGGTCCATCACGCCCATC ATGTACCCGGCCTCCTTCTGGTTCGAGGTCCCCAGCTCCGCCTACGTGTTCCTCATTGTCATCAATCTCT TCATCGGCATCACCGCCACCGTGGCCACCTTCCTGCTACAGCTCTTCGAGCACGACAAGGACCTGAAGGT TGTCAACAGTTACCTGAAAAGCTGCTTCCTCATTTTCCCCAACTACAACCTGGGCCACGGGCTCATGGAG ATGGCCTACAACGAGTACATCAACGAGTACTACGCCAAGATTGGCCAGTTTGACAAGATGAAGTCCCCGT TCGAGTGGGACATTGTCACCCGCGGACTGGTGGCCATGGCGGTTGAGGGCGTCGTGGGCTTCCTCCTGAC CATCATGTGCCAGTACAACTTCCTGCGGCGGCCACAGCGCATGCCTGTGTCTACCAAGCCTGTGGAGGAT GATGTGGACGTGGCCAGTGAGCGGCAGCGAGTGCTCCGGGGAGACGCCGACAATGACATGGTCAAGATTG AGAACCTGACCAAGGTCTACAAGTCCCGGAAGATTGGCCGTATCCTGGCCGTTGACCGCCTGTGCCTGGG TGTGCGTCCTGGCGAGTGCTTCGGGCTCCTGGGCGTCAACGGTGCGGGCAAGACCAGCACCTTCAAGATG CTGACCGGCGACGAGAGCACGACGGGGGGCGAGGCCTTCGTCAATGGACACAGCGTGCTGAAGGAGCTGC TCCAGGTGCAGCAGAGCCTCGGCTACTGCCCGCAGTGTGACGCGCTGTTCGACGAGCTCACGGCCCGGGA GCACCTGCAGCTGTACACGCGGCTGCGTGGGATCTCCTGGAAGGACGAGGCCCGGGTGGTGAAGTGGGCT CTGGAGAAGCTGGAGCTGACCAAGTACGCAGACAAGCCGGCTGGCACCTACAGCGGCGGCAACAAGCGGA AGCTCTCCACGGCCATCGCCCTCATTGGGTACCCAGCCTTCATCTTCCTGGACGAGCCCACCACAGGCAT GGACCCCAAGGCCCGGCGCTTCCTCTGGAACCTCATCCTTGACCTCATCAAGACAGGGCGTTCAGTGGTG CTGACATCACACAGCATGGAGGAGTGCGAGGCGCTGTGCACGCGGCTGGCCATCATGGTGAACGGTCGCC TGCGGTGCCTGGGCAGCATCCAGCACCTGAAGAACCGGTTTGGAGATGGCTACATGATCACGGTGCGGAC CAAGAGCAGCCAGAGTGTGAAGGACGTGGTGCGGTTCTTCAACCGCAACTTCCCGGAAGCCATGCTCAAG GAGCGGCACCACACAAAGGTGCAGTACCAGCTCAAGTCGGAGCACATCTCGCTGGCCCAGGTGTTCAGCA AGATGGAGCAGGTGTCTGGCGTGCTGGGCATCGAGGACTACTCGGTCAGCCAGACCACACTGGACAATGT GTTCGTGAACTTTGCCAAGAAGCAGAGTGACAACCTGGAGCAGCAGGAGACGGAGCCGCCATCCGCACTG CAGTCCCCTCTCGGCTGCTTGCTCAGCCTGCTCCGGCCCCGGTCTGCCCCCACGGAGCTCCGGGCACTTG TGGCAGACGAGCCCGAGGACCTGGACACGGAGGACGAGGGCCTCATCAGCTTCGAGGAGGAGCGGGCCCA GCTGTCCTTCAACACGGACACGCTCTGC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG216059 representing NM_001606
Red=Cloning site Green=Tags(s) MGFLHQLQLLLWKNVTLKRRSPWVLAFEIFIPLVLFFILLGLRQKKPTISVKEVSFYTAAPLTSAGILPV MQSLCPDGQRDEFGFLQYANSTVTQLLERLDRVVEEGNLFDPARPSLGSELEALRQHLEALSAGPGTSGS HLDRSTVSSFSLDSVARNPQELWRFLTQNLSLPNSTAQALLAARVDPPEVYHLLFGPSSALDSQSGLHKG QEPWSRLGGNPLFRMEELLLAPALLEQLTCTPGSGELGRILTVPESQKGALQGYRDAVCSGQAAARARRF SGLSAELRNQLDVAKVSQQLGLDAPNGSDSSPQAPPPRRLQALLGDLLDAQKVLQDVDVLSALALLLPQG ACTGRTPGPPASGAGGAANGTGAGAVMGPNATAEEGAPSAAALATPDTLQGQCSAFVQLWAGLQPILCGN NRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKILYAPAGSEVDRVILKANETFAFVGNVTHYA QVWLNISAEIRSFLEQGRLQQHLRWLQQYVAELRLHPEALNLSLDELPPALRQDNFSLPSGMALLQQLDT IDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQDNVTVFASVIFQTRKDGSLPPHVHYKIRQNS SFTEKTNEIRRAYWRPGPNTGGRFYFLYGFVWIQDMMERAIIDTFVGHDVVEPGSYVQMFPYPCYTRDDF LFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMKTMGLNNAVHWVAWFITGFVQLSISVTALTA ILKYGQVLMHSHVVIIWLFLAVYAVATIMFCFLVSVLYSKAKLASACGGIIYFLSYVPYMYVAIREEVAH DKITAFEKCIASLMSTTAFGLGSKYFALYEVAGVGIQWHTFSQSPVEGDDFNLLLAVTMLMVDAVVYGIL TWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTEAWEWSWPWARTPRLSVMEEDQACAMESRRFEETRGM EEEPTHLPLVVCVDKLTKVYKDDKKLALNKLSLNLYENQVVSFLGHNGAGKTTTMSILTGLFPPTSGSAT IYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRLKSMAQEEIRREMDKMIEDLELSNKRHSL VQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARRAIWDLILKYKPGRTILLSTHHMDEADLLGD RIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGGPQEPGLASSPPGRAPLSSCSELQVSQFIRK HVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSLDALHLSSFGLMDTTLEEVFLKVSEEDQSLE NSEADVKESRKDVLPGAEGPASGEGHAGNLARCSELTQSQASLQSASSVGSARGDEGAGYTDVYGDYRPL FDNPQDPDNVSLQEVEAEALSRVGQGSRKLDGGWLKVRQFHGLLVKRFHCARRNSKALFSQILLPAFFVC VAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYANEERREYRLRLSPDASPQQLVSTFRLPSGVG ATCVLKSPANGSLGPTLNLSSGESRLLAARFFDSMCLESFTQGLPLSNFVPPPPSPAPSDSPASPDEDLQ AWNVSLPPTAGPEMWTSAPSLPRLVREPVRCTCSAQGTGFSCPSSVGGHPPQMRVVTGDILTDITGHNVS EYLLFTSDRFRLHRYGAITFGNVLKSIPASFGTRAPPMVRKIAVRRAAQVFYNNKGYHSMPTYLNSLNNA ILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQGTDVVIAIFIIVAMSFVPASFVVFLVAEKST KAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILFVFDLPAYTSPTNFPAVLSLFLLYGWSITPI MYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFEHDKDLKVVNSYLKSCFLIFPNYNLGHGLME MAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMAVEGVVGFLLTIMCQYNFLRRPQRMPVSTKPVED DVDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILAVDRLCLGVRPGECFGLLGVNGAGKTSTFKM LTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALFDELTAREHLQLYTRLRGISWKDEARVVKWA LEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFLDEPTTGMDPKARRFLWNLILDLIKTGRSVV LTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDGYMITVRTKSSQSVKDVVRFFNRNFPEAMLK ERHHTKVQYQLKSEHISLAQVFSKMEQVSGVLGIEDYSVSQTTLDNVFVNFAKKQSDNLEQQETEPPSAL QSPLGCLLSLLRPRSAPTELRALVADEPEDLDTEDEGLISFEEERAQLSFNTDTLC TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001606 |
| ORF Size | 7308 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001606.5 |
| RefSeq Size | 8171 bp |
| RefSeq ORF | 7311 bp |
| Locus ID | 20 |
| UniProt ID | Q9BZC7 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ABC transporters, Lysosome |
| Gene Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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