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PTPN13 (NM_080683) Human Tagged ORF Clone
CAT＃: RG214221
- TrueORF®
PTPN13 (tGFP-tagged) - Human protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 1
ORF Plasmid: DDK
"NM_080683" in other vectors (2)
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CNY 20,900.00
货期*
12周
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG214221 representing NM_080683
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCACGTGTCACTAGCTGAGGCCCTGGAGGTTCGGGGTGGACCACTTCAGGAGGAAGAAATATGGGCTG TATTAAATCAAAGTGCTGAAAGTCTCCAAGAATTATTCAGAAAAGTAAGCCTAGCTGATCCTGCTGCCCT TGGCTTCATCATTTCTCCATGGTCTCTGCTGTTGCTGCCATCTGGTAGTGTGTCATTTACAGATGAAAAT ATTTCCAATCAGGATCTTCGAGCATTCACTGCACCAGAGGTTCTTCAAAATCAGTCACTAACTTCTCTCT CAGATGTTGAAAAGATCCACATTTATTCTCTTGGAATGACACTGTATTGGGGGGCTGATTATGAAGTGCC TCAGAGCCAACCTATTAAGCTTGGAGATCATCTCAACAGCATACTGCTTGGAATGTGTGAGGATGTTATT TACGCTCGAGTTTCTGTTCGGACTGTGCTGGATGCTTGCAGTGCCCACATTAGGAATAGCAATTGTGCAC CCTCATTTTCCTACGTGAAACACTTGGTAAAACTGGTTCTGGGAAATCTTTCTGGGACAGATCAGCTTTC CTGTAACAGTGAACAAAAGCCTGATCGAAGCCAGGCTATTCGAGATCGATTGCGAGGAAAAGGATTACCA ACAGGAAGAAGCTCTACTTCTGATGTACTAGACATACAAAAGCCTCCACTCTCTCATCAGACCTTTCTTA ACAAAGGGCTTAGTAAATCTATGGGATTTCTGTCCATCAAAGATACACAAGATGAGAATTATTTCAAGGA CATTTTATCAGATAATTCTGGACGTGAAGATTCTGAAAATACATTCTCCCCTTACCAGTTCAAAACTAGT GGCCCAGAAAAAAAACCCATCCCTGGCATTGATGTGCTTTCTAAGAAGAAGATCTGGGCTTCATCCATGG ACTTGCTTTGTACAGCTGACAGAGACTTCTCTTCAGGAGAGACTGCCACATATCGTCGTTGTCACCCTGA GGCAGTAACAGTGCGGACTTCAACTACTCCTAGAAAAAAGGAGGCAAGATACTCAGATGGAAGTATAGCC TTGGATATCTTTGGCCCTCAGAAAATGGATCCAATATATCACACTCGAGAATTGCCCACCTCCTCAGCAA TATCAAGTGCTTTGGACCGAATCCGAGAGAGACAAAAGAAACTTCAGGTTCTGAGGGAAGCCATGAATGT AGAAGAACCAGTTCGAAGATACAAAACTTATCATGGTGATGTCTTTAGTACCTCCAGTGAAAGTCCATCT ATTATTTCCTCTGAATCAGATTTCAGACAAGTGAGAAGAAGTGAAGCCTCAAAGAGGTTTGAATCCAGCA GTGGTCTCCCAGGGGTAGATGAAACCTTAAGTCAAGGCCAGTCACAGAGACCGAGCAGACAATATGAAAC ACCCTTTGAAGGCAACTTAATTAATCAAGAGATCATGCTAAAACGGCAAGAGGAAGAACTGATGCAGCTA CAAGCCAAAATGGCCCTTAGACAGTCTCGGTTGAGCCTATATCCAGGAGACACAATCAAAGCGTCCATGC TTGACATCACCAGGGATCCGTTAAGAGAAATTGCCCTAGAAACAGCCATGACTCAAAGAAAACTGAGGAA TTTCTTTGGCCCTGAGTTTGTGAAAATGACAATTGAACCATTTATATCTTTGGATTTGCCACGGTCTATT CTTACTAAGAAAGGGAAGAATGAGGATAACCGAAGGAAAGTAAACATAATGCTTCTGAACGGGCAAAGAC TGGAACTGACCTGTGATACCAAAACTATATGTAAAGATGTGTTTGATATGGTTGTGGCACATATTGGCTT AGTAGAGCATCATTTGTTTGCTTTAGCTACCCTCAAAGATAATGAATATTTCTTTGTTGATCCTGACTTA AAATTAACCAAAGTGGCCCCAGAGGGATGGAAAGAAGAACCAAAGAAAAAGACCAAAGCCACTGTTAATT TTACTTTGTTTTTCAGAATTAAATTTTTTATGGATGATGTTAGTCTAATACAACATACTCTGACGTGTCA TCAGTATTACCTTCAGCTTCGAAAAGATATTTTGGAGGAAAGGATGCACTGTGATGATGAGACTTCCTTA TTGCTGGCATCCTTGGCTCTCCAGGCTGAGTATGGAGATTATCAACCAGAGGTTCATGGTGTGTCTTACT TTAGAATGGAGCACTATTTGCCCGCCAGAGTGATGGAGAAACTTGATTTATCCTATATCAAAGAAGAGTT ACCCAAATTGCATAATACCTATGTGGGAGCTTCTGAAAAAGAGACAGAGTTAGAATTTTTAAAGGTCTGC CAAAGACTGACAGAATATGGAGTTCATTTTCACCGAGTGCACCCTGAGAAGAAGTCACAAACAGGAATAT TGCTTGGAGTCTGTTCTAAAGGTGTCCTTGTGTTTGAAGTTCACAATGGAGTGCGCACATTGGTCCTTCG CTTTCCATGGAGGGAAACCAAGAAAATATCTTTTTCTAAAAAGAAAATCACATTGCAAAATACATCAGAT GGAATAAAACATGGCTTCCAGACAGACAACAGTAAGATATGCCAGTACCTGCTGCACCTCTGCTCTTACC AGCATAAGTTCCAGCTACAGATGAGAGCAAGACAGAGCAACCAAGATGCCCAAGATATTGAGAGAGCTTC GTTTAGGAGCCTGAATCTCCAAGCAGAGTCTGTTAGAGGATTTAATATGGGACGAGCAATCAGCACTGGC AGTCTGGCCAGCAGCACCCTCAACAAACTTGCTGTTCGACCTTTATCAGTTCAAGCTGAGATTCTGAAGA GGCTATCCTGCTCAGAGCTGTCGCTTTACCAGCCATTGCAAAACAGTTCAAAAGAGAAGAATGACAAAGC TTCATGGGAGGAAAAGCCTAGAGAGATGAGTAAATCATACCATGATCTCAGTCAGGCCTCTCTCTATCCA CATCGGAAAAATGTCATTGTTAACATGGAACCCCCACCACAAACCGTTGCAGAGTTGGTGGGAAAACCTT CTCACCAGATGTCAAGATCTGATGCAGAATCTTTGGCAGGAGTGACAAAACTTAATAATTCAAAGTCTGT TGCGAGTTTAAATAGAAGTCCTGAAAGGAGGAAACATGAATCAGACTCCTCATCCATTGAAGACCCTGGG CAAGCATATGTTCTAGGAATGACTATGCATAGTTCTGGAAACTCTTCATCCCAAGTACCCTTAAAAGAAA ATGATGTGCTACACAAAAGATGGAGCATAGTATCTTCACCAGAAAGGGAGATCACCTTAGTGAACCTGAA AAAAGATGCAAAGTATGGCTTGGGATTTCAAATTATTGGTGGGGAGAAGATGGGAAGACTGGACCTAGGC ATATTTATCAGTTCAGTTGCCCCTGGAGGACCAGCTGACTTGGATGGATGCTTGAAGCCAGGAGACCGTT TGATATCTGTGAATAGTGTGAGTCTGGAGGGAGTCAGCCACCATGCTGCAATTGAAATTTTGCAAAATGC ACCTGAAGATGTGACACTTGTTATCTCTCAGCCAAAAGAAAAGATATCCAAAGTGCCTTCTACTCCTGTG CATCTCACCAATGAGATGAAAAACTACATGAAGAAATCTTCCTACATGCAAGACAGTGCTATAGATTCTT CTTCCAAGGATCACCACTGGTCACGTGGTACCCTGAGGCACATCTCGGAGAACTCCTTTGGGCCATCTGG GGGCCTGCGGGAAGGAAGCCTGAGTTCTCAAGATTCCAGGACTGAGAGTGCCAGCTTGTCTCAAAGCCAG GTCAATGGTTTCTTTGCCAGCCATTTAGGTGACCAAACCTGGCAGGAATCACAGCATGGCAGCCCTTCCC CATCTGTAATATCCAAAGCCACCGAGAAAGAGACTTTCACTGATAGTAACCAAAGCAAAACTAAAAAGCC AGGCATTTCTGATGTAACTGATTACTCAGACCGTGGAGATTCAGACATGGATGAAGCCACTTACTCCAGC AGTCAGGATCATCAAACACCAAAACAGGAATCTTCCTCTTCAGTGAATACATCCAACAAGATGAATTTTA AAACTTTTTCTTCATCACCTCCTAAGCCTGGAGATATCTTTGAGGTTGAACTGGCTAAAAATGATAACAG CTTGGGGATAAGTGTCACGGGAGGTGTGAATACGAGTGTCAGACATGGTGGCATTTATGTGAAAGCTGTT ATTCCCCAGGGAGCAGCAGAGTCTGATGGTAGAATTCACAAAGGTGATCGCGTCCTAGCTGTCAATGGAG TTAGTCTAGAAGGAGCCACCCATAAGCAAGCTGTGGAAACACTGAGAAATACAGGACAGGTGGTTCATCT GTTATTAGAAAAGGGACAATCTCCAACATCTAAAGAACATGTCCCGGTAACCCCACAGTGTACCCTTTCA GATCAGAATGCCCAAGGTCAAGGCCCAGAAAAAGTGAAGAAAACAACTCAGGTCAAAGACTACAGCTTTG TCACTGAAGAAAATACATTTGAGGTAAAATTATTTAAAAATAGCTCAGGTCTAGGATTCAGTTTTTCTCG AGAAGATAATCTTATACCGGAGCAAATTAATGCCAGCATAGTAAGGGTTAAAAAGCTCTTTCCTGGACAG CCAGCAGCAGAAAGTGGAAAAATTGATGTAGGAGATGTTATCTTGAAAGTGAATGGAGCCTCTTTGAAAG GACTATCTCAGCAGGAAGTCATATCTGCTCTCAGGGGAACTGCTCCAGAAGTATTCTTGCTTCTCTGCAG ACCTCCACCTGGTGTGCTACCGGAAATTGATACTGCGCTTTTGACCCCACTTCAGTCTCCAGCACAAGTA CTTCCAAACAGCAGTAAAGACTCTTCTCAGCCATCATGTGTGGAGCAAAGCACCAGCTCAGATGAAAATG AAATGTCAGACAAAAGCAAAAAACAGTGCAAGTCCCCATCCAGAAGAGACAGTTACAGTGACAGCAGTGG GAGTGGAGAAGATGACTTAGTGACAGCTCCAGCAAACATATCAAATTCGACCTGGAGTTCAGCTTTGCAT CAGACTCTAAGCAACATGGTATCACAGGCACAGAGTCATCATGAAGCACCCAAGAGTCAAGAAGATACCA TTTGTACCATGTTTTACTATCCTCAGAAAATTCCCAATAAACCAGAGTTTGAGGACAGTAATCCTTCCCC TCTACCACCGGATATGGCTCCTGGGCAGAGTTATCAACCCCAATCAGAATCTGCTTCCTCTAGTTCGATG GATAAGTATCATATACATCACATTTCTGAACCAACTAGACAAGAAAACTGGACACCTTTGAAAAATGACT TGGAAAATCACCTTGAAGACTTTGAACTGGAAGTAGAACTCCTCATTACCCTAATTAAATCAGAAAAAGG AAGCCTGGGTTTTACAGTAACCAAAGGCAATCAGAGAATTGGTTGTTATGTTCATGATGTCATACAGGAT CCAGCCAAAAGTGATGGAAGGCTAAAACCTGGGGACCGGCTCATAAAGGTTAATGATACAGATGTTACTA ATATGACTCATACAGATGCAGTTAATCTGCTCCGGGCTGCATCCAAAACAGTCAGATTAGTTATTGGACG AGTTCTAGAATTACCCAGAATACCAATGTTGCCTCATTTGCTACCGGACATAACACTAACGTGCAACAAA GAGGAGTTGGGTTTTTCCTTATGTGGAGGTCATGACAGCCTTTATCAAGTGGTATATATTAGTGATATTA ATCCAAGGTCCGTCGCAGCCATTGAGGGTAATCTCCAGCTATTAGATGTCATCCATTATGTGAACGGAGT CAGCACACAAGGAATGACCTTGGAGGAAGTTAACAGAGCATTAGACATGTCACTTCCTTCATTGGTATTG AAAGCAACAAGAAATGATCTTCCAGTGGTCCCCAGCTCAAAGAGGTCTGCTGTTTCAGCTCCAAAGTCAA CCAAAGGCAATGGTTCCTACAGTGTGGGGTCTTGCAGCCAGCCTGCCCTCACTCCTAATGATTCATTCTC CACGGTTGCTGGGGAAGAAATAAATGAAATATCGTACCCCAAAGGAAAATGTTCTACTTATCAGATAAAG GGATCACCAAACTTGACTCTGCCCAAAGAATCTTATATACAAGAAGATGACATTTATGATGATTCCCAAG AAGCTGAAGTTATCCAGTCTCTGCTGGATGTTGTGGATGAGGAAGCCCAGAATCTTTTAAACGAAAATAA TGCAGCAGGATACTCCTGTGGTCCAGGTACATTAAAGATGAATGGGAAGTTATCAGAAGAGAGAACAGAA GATACAGACTGCGATGGTTCACCTTTACCTGAGTATTTTACTGAGGCCACCAAAATGAATGGCTGTGAAG AATATTGTGAAGAAAAAGTAAAAAGTGAAAGCTTAATTCAGAAGCCACAAGAAAAGAAGACTGATGATGA TGAAATAACATGGGGAAATGATGAGTTGCCAATAGAGAGAACAAACCATGAAGATTCTGATAAAGATCAT TCCTTTCTGACAAACGATGAGCTCGCTGTACTCCCTGTCGTCAAAGTGCTTCCCTCTGGTAAATACACGG GTGCCAACTTAAAATCAGTCATTCGAGTCCTGCGGGGTTTGCTAGATCAAGGAATTCCTTCTAAGGAGCT GGAGAATCTTCAAGAATTAAAACCTTTGGATCAGTGTCTAATTGGGCAAACTAAGGAAAACAGAAGGAAG AACAGATATAAAAATATACTTCCCTATGATGCTACAAGAGTGCCTCTTGGAGATGAAGGTGGCTATATCA ATGCCAGCTTCATTAAGATACCAGTTGGGAAAGAAGAGTTCGTTTACATTGCCTGCCAAGGACCACTGCC TACAACTGTTGGAGACTTCTGGCAGATGATTTGGGAGCAAAAATCCACAGTGATAGCCATGATGACTCAA GAAGTAGAAGGAGAAAAAATCAAATGCCAGCGCTATTGGCCCAACATCCTAGGCAAAACAACAATGGTCA GCAACAGACTTCGACTGGCTCTTGTGAGAATGCAGCAGCTGAAGGGCTTTGTGGTGAGGGCAATGACCCT TGAAGATATTCAGACCAGAGAGGTGCGCCATATTTCTCATCTGAATTTCACTGCCTGGCCAGACCATGAT ACACCTTCTCAACCAGATGATCTGCTTACTTTTATCTCCTACATGAGACACATCCACAGATCAGGCCCAA TCATTACGCACTGCAGTGCTGGCATTGGACGTTCAGGGACCCTGATTTGCATAGATGTGGTTCTGGGATT AATCAGTCAGGATCTTGATTTTGACATCTCTGATTTGGTGCGCTGCATGAGACTACAAAGACACGGAATG GTTCAGACAGAGGATCAATATATTTTCTGCTATCAAGTCATCCTTTATGTCCTGACACGTCTTCAAGCAG AAGAAGAGCAAAAACAGCAGCCTCAGCTTCTGAAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG214221 representing NM_080683
Red=Cloning site Green=Tags(s) MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSGSVSFTDEN ISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPIKLGDHLNSILLGMCEDVI YARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNLSGTDQLSCNSEQKPDRSQAIRDRLRGKGLP TGRSSTSDVLDIQKPPLSHQTFLNKGLSKSMGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTS GPEKKPIPGIDVLSKKKIWASSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIA LDIFGPQKMDPIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIMLKRQEEELMQL QAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFGPEFVKMTIEPFISLDLPRSI LTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDL KLTKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSL LLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVC QRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRGFNMGRAISTG SLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYP HRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPG QAYVLGMTMHSSGNSSSQVPLKENDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLG IFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPV HLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSS SQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAV IPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLS DQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQ PAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQV LPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSM DKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQD PAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNK EELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVL KATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIK GSPNLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDH SFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRK NRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQ EVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHD TPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGM VQTEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_080683 |
| ORF Size | 7455 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_080683.3 |
| RefSeq Size | 8573 bp |
| RefSeq ORF | 7458 bp |
| Locus ID | 5783 |
| UniProt ID | Q12923 |
| Domains | Y_phosphatase, B41, PDZ, PTPc_motif |
| Protein Families | Druggable Genome, Phosphatase |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214221 | PTPN13 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 1 |
CNY 26,248.00 |
|
| SC128005 | PTPN13 (untagged)-Human protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 1 |
CNY 24,616.00 |
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