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Frizzled 6 (FZD6) (NM_001164616) Human Tagged ORF Clone
CAT＃: RC228994
- TrueORF®
FZD6 (Myc-DDK-tagged)-Human frizzled family receptor 6 (FZD6), transcript variant 3
ORF Plasmid: tGFP
"NM_001164616" in other vectors (4)
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CNY 6,750.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | FZ-6; FZ6; HFZ6; NDNC1; NDNC10 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC228994 representing NM_001164616
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAAATGGCCTACAACATGACGTTTTTCCCTAATCTGATGGGTCATTATGACCAGAGTATTGCCGCGG TGGAAATGGAGCATTTTCTTCCTCTCGCAAATCTGGAATGTTCACCAAACATTGAAACTTTCCTCTGCAA AGCATTTGTACCAACCTGCATAGAACAAATTCATGTGGTTCCACCTTGTCGTAAACTTTGTGAGAAAGTA TATTCTGATTGCAAAAAATTAATTGACACTTTTGGGATCCGATGGCCTGAGGAGCTTGAATGTGACAGAT TACAATACTGTGATGAGACTGTTCCTGTAACTTTTGATCCACACACAGAATTTCTTGGTCCTCAGAAGAA AACAGAACAAGTCCAAAGAGACATTGGATTTTGGTGTCCAAGGCATCTTAAGACTTCTGGGGGACAAGGA TATAAGTTTCTGGGAATTGACCAGTGTGCGCCTCCATGCCCCAACATGTATTTTAAAAGTGATGAGCTAG AGTTTGCAAAAAGTTTTATTGGAACAGTTTCAATATTTTGTCTTTGTGCAACTCTGTTCACATTCCTTAC TTTTTTAATTGATGTTAGAAGATTCAGATACCCAGAGAGACCAATTATATATTACTCTGTCTGTTACAGC ATTGTATCTCTTATGTACTTCATTGGATTTTTGCTAGGCGATAGCACAGCCTGCAATAAGGCAGATGAGA AGCTAGAACTTGGTGACACTGTTGTCCTAGGCTCTCAAAATAAGGCTTGCACCGTTTTGTTCATGCTTTT GTATTTTTTCACAATGGCTGGCACTGTGTGGTGGGTGATTCTTACCATTACTTGGTTCTTAGCTGCAGGA AGAAAATGGAGTTGTGAAGCCATCGAGCAAAAAGCAGTGTGGTTTCATGCTGTTGCATGGGGAACACCAG GTTTCCTGACTGTTATGCTTCTTGCTATGAACAAAGTTGAAGGAGACAACATTAGTGGAGTTTGCTTTGT TGGCCTTTATGACCTGGATGCTTCTCGCTACTTTGTACTCTTGCCACTGTGCCTTTGTGTGTTTGTTGGG CTCTCTCTTCTTTTAGCTGGCATTATTTCCTTAAATCATGTTCGACAAGTCATACAACATGATGGCCGGA ACCAAGAAAAACTAAAGAAATTTATGATTCGAATTGGAGTCTTCAGCGGCTTGTATCTTGTGCCATTAGT GACACTTCTCGGATGTTACGTCTATGAGCAAGTGAACAGGATTACCTGGGAGATAACTTGGGTCTCTGAT CATTGTCGTCAGTACCATATCCCATGTCCTTATCAGGCAAAAGCAAAAGCTCGACCAGAATTGGCTTTAT TTATGATAAAATACCTGATGACATTAATTGTTGGCATCTCTGCTGTCTTCTGGGTTGGAAGCAAAAAGAC ATGCACAGAATGGGCTGGGTTTTTTAAACGAAATCGCAAGAGAGATCCAATCAGTGAAAGTCGAAGAGTA CTACAGGAATCATGTGAGTTTTTCTTAAAGCACAATTCTAAAGTTAAACACAAAAAGAAGCACTATAAAC CAAGTTCACACAAGCTGAAGGTCATTTCCAAATCCATGGGAACCAGCACAGGAGCTACAGCAAATCATGG CACTTCTGCAGTAGCAATTACTAGCCATGATTACCTAGGACAAGAAACTTTGACAGAAATCCAAACCTCA CCAGAAACATCAATGAGAGAGGTGAAAGCGGACGGAGCTAGCACCCCCAGGTTAAGAGAACAGGACTGTG GTGAACCTGCCTCGCCAGCAGCATCCATCTCCAGACTCTCTGGGGAACAGGTCGACGGGAAGGGCCAGGC AGGCAGTGTATCTGAAAGTGCGCGGAGTGAAGGAAGGATTAGTCCAAAGAGTGATATTACTGACACTGGC CTGGCACAGAGCAACAATTTGCAGGTCCCCAGTTCTTCAGAACCAAGCAGCCTCAAAGGTTCCACATCTC TGCTTGTTCACCCGGTTTCAGGAGTGAGAAAAGAGCAGGGAGGTGGTTGTCATTCAGATACT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC228994 representing NM_001164616
Red=Cloning site Green=Tags(s) MKMAYNMTFFPNLMGHYDQSIAAVEMEHFLPLANLECSPNIETFLCKAFVPTCIEQIHVVPPCRKLCEKV YSDCKKLIDTFGIRWPEELECDRLQYCDETVPVTFDPHTEFLGPQKKTEQVQRDIGFWCPRHLKTSGGQG YKFLGIDQCAPPCPNMYFKSDELEFAKSFIGTVSIFCLCATLFTFLTFLIDVRRFRYPERPIIYYSVCYS IVSLMYFIGFLLGDSTACNKADEKLELGDTVVLGSQNKACTVLFMLLYFFTMAGTVWWVILTITWFLAAG RKWSCEAIEQKAVWFHAVAWGTPGFLTVMLLAMNKVEGDNISGVCFVGLYDLDASRYFVLLPLCLCVFVG LSLLLAGIISLNHVRQVIQHDGRNQEKLKKFMIRIGVFSGLYLVPLVTLLGCYVYEQVNRITWEITWVSD HCRQYHIPCPYQAKAKARPELALFMIKYLMTLIVGISAVFWVGSKKTCTEWAGFFKRNRKRDPISESRRV LQESCEFFLKHNSKVKHKKKHYKPSSHKLKVISKSMGTSTGATANHGTSAVAITSHDYLGQETLTEIQTS PETSMREVKADGASTPRLREQDCGEPASPAASISRLSGEQVDGKGQAGSVSESARSEGRISPKSDITDTG LAQSNNLQVPSSSEPSSLKGSTSLLVHPVSGVRKEQGGGCHSDT TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001164616 |
| ORF Size | 2022 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001164616.2 |
| RefSeq Size | 3691 bp |
| RefSeq ORF | 2025 bp |
| Locus ID | 8323 |
| UniProt ID | O60353 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| MW | 75.6 kDa |
| Gene Summary | This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC228994L3 | Lenti-ORF clone of FZD6 (Myc-DDK-tagged)-Human frizzled family receptor 6 (FZD6), transcript variant 3 |
CNY 8,650.00 |
|
| RC228994L4 | Lenti-ORF clone of FZD6 (mGFP-tagged)-Human frizzled family receptor 6 (FZD6), transcript variant 3 |
CNY 8,650.00 |
|
| RG228994 | FZD6 (tGFP-tagged) - Human frizzled family receptor 6 (FZD6), transcript variant 3 |
CNY 7,410.00 |
|
| SC327629 | FZD6 (untagged)-Human frizzled homolog 6 (Drosophila) (FZD6) transcript variant 3 |
CNY 13,110.00 |
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