ABCA2 (NM_212533) Human Tagged ORF Clone

Specifications

Product Data
Type	Human Tagged ORF Clone
Tag	Myc-DDK
Synonyms	ABC2; IDPOGSA
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >RC216007 representing NM_212533 Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGAGAAAAACGAGCCGCGTGCAGCAGGGGCCGCCTCGGTCCCCTGCCTGCTCCGCCCACGGCGAGC GTTCCTGGGGCCTCGAGTTTCCCCCCTTCCGCTGGCTGCTCGGAATCGCGGGACGGACCCACCTGGCCGC CCTGCCTCCCTTCCAGTGGGTCCTGGCCTTCGAGATCTTCATCCCCCTGGTGCTGTTCTTTATCCTGCTG GGGCTGCGACAGAAGAAGCCCACCATCTCCGTGAAGGAAGTCTCCTTCTACACAGCGGCGCCCCTGACGT CTGCCGGCATCCTGCCTGTCATGCAATCGCTGTGCCCGGACGGCCAGCGAGACGAGTTCGGCTTCCTGCA GTACGCCAACTCCACGGTCACGCAGCTGCTTGAGCGCCTGGACCGCGTGGTGGAGGAAGGCAACCTGTTT GACCCAGCGCGGCCCAGCCTGGGCTCAGAGCTCGAGGCCCTACGCCAGCATCTGGAGGCCCTCAGTGCGG GCCCGGGCACCTCGGGGAGCCACCTGGACAGATCCACAGTGTCTTCCTTCTCTCTGGACTCGGTGGCCAG AAACCCGCAGGAGCTCTGGCGTTTCCTGACGCAAAACTTGTCGCTGCCCAATAGCACGGCCCAAGCACTC TTGGCCGCCCGTGTGGACCCGCCCGAGGTCTACCACCTGCTCTTTGGTCCCTCATCTGCCCTGGATTCAC AGTCTGGCCTCCACAAGGGTCAGGAGCCCTGGAGCCGCCTAGGGGGCAATCCCCTGTTCCGGATGGAGGA GCTGCTGCTGGCTCCTGCCCTCCTGGAGCAGCTCACCTGCACGCCGGGCTCGGGGGAGCTGGGCCGGATC CTCACTGTGCCTGAGAGTCAGAAGGGAGCCCTGCAGGGCTACCGGGATGCTGTCTGCAGTGGGCAGGCTG CTGCGCGTGCCAGGCGCTTCTCTGGGCTGTCTGCTGAGCTCCGGAACCAGCTGGACGTGGCCAAGGTCTC CCAGCAGCTGGGCCTGGATGCCCCCAACGGCTCGGACTCCTCGCCACAGGCGCCACCCCCACGGAGGCTG CAGGCGCTTCTGGGGGACCTGCTGGATGCCCAGAAGGTTCTGCAGGATGTGGATGTCCTGTCGGCCCTGG CCCTGCTACTGCCCCAGGGTGCCTGCACTGGCCGGACCCCCGGACCCCCAGCCAGTGGTGCGGGTGGGGC GGCCAATGGCACTGGGGCAGGGGCAGTCATGGGCCCCAACGCCACCGCTGAGGAGGGCGCACCCTCTGCT GCAGCACTGGCCACCCCGGACACGCTGCAGGGCCAGTGCTCAGCCTTCGTACAGCTCTGGGCCGGCCTGC AGCCCATCTTGTGTGGCAACAACCGCACCATTGAACCCGAGGCGCTGCGGCGGGGCAACATGAGCTCCCT GGGCTTCACGAGCAAGGAGCAGCGGAACCTGGGCCTCCTCGTGCACCTCATGACCAGCAACCCCAAAATC CTGTACGCGCCTGCGGGCTCTGAGGTCGACCGCGTCATCCTCAAGGCCAACGAGACTTTTGCTTTTGTGG GCAACGTGACTCACTATGCCCAGGTCTGGCTCAACATCTCGGCGGAGATCCGCAGCTTCCTGGAGCAGGG CAGGCTGCAGCAACACCTGCGCTGGCTGCAGCAGTATGTAGCAGAGCTGCGGCTGCACCCCGAGGCACTG AACCTGTCACTGGATGAGCTGCCGCCGGCCCTGAGACAGGACAACTTCTCGCTGCCCAGTGGCATGGCCC TCCTGCAGCAGCTGGATACCATTGACAACGCGGCCTGCGGCTGGATCCAGTTCATGTCCAAGGTGAGCGT GGACATCTTCAAGGGCTTCCCCGACGAGGAGAGCATTGTCAACTACACCCTCAACCAGGCCTACCAGGAC AACGTCACTGTTTTTGCCAGTGTGATCTTCCAGACCCGGAAGGACGGCTCGCTCCCGCCTCACGTGCACT ACAAGATCCGCCAGAACTCCAGCTTCACCGAGAAAACCAACGAGATCCGCCGCGCCTACTGGCGGCCTGG GCCCAATACTGGCGGCCGCTTCTACTTCCTCTACGGCTTCGTCTGGATCCAGGACATGATGGAGCGCGCC ATCATCGACACTTTTGTGGGGCACGACGTGGTGGAGCCAGGCAGCTACGTGCAGATGTTCCCCTACCCCT GCTACACACGCGATGACTTCCTGTTTGTCATTGAGCACATGATGCCGCTGTGCATGGTGATCTCCTGGGT CTACTCCGTGGCCATGACCATCCAGCACATCGTGGCGGAGAAGGAGCACCGGCTCAAGGAGGTGATGAAG ACCATGGGCCTGAACAACGCGGTGCACTGGGTGGCCTGGTTCATCACCGGCTTTGTGCAGCTGTCCATCT CCGTGACAGCACTCACCGCCATCCTGAAGTACGGCCAGGTGCTTATGCACAGCCACGTGGTCATCATCTG GCTCTTCCTGGCAGTCTACGCGGTGGCCACCATCATGTTCTGCTTCCTGGTGTCTGTGCTGTACTCCAAG GCCAAGCTGGCCTCGGCCTGCGGTGGCATCATCTACTTCCTGAGCTACGTGCCCTACATGTACGTGGCGA TCCGAGAGGAGGTGGCGCATGATAAGATCACGGCCTTCGAGAAGTGCATCGCGTCCCTCATGTCCACGAC GGCCTTTGGTCTGGGCTCTAAGTACTTCGCGCTGTATGAGGTGGCCGGCGTGGGCATCCAGTGGCACACC TTCAGCCAGTCCCCGGTGGAGGGGGACGACTTCAACTTGCTCCTGGCTGTCACCATGCTGATGGTGGACG CCGTGGTCTATGGCATCCTCACGTGGTACATTGAGGCTGTGCACCCAGGCATGTACGGGCTGCCCCGGCC CTGGTACTTCCCACTGCAGAAGTCCTACTGGCTGGGCAGTGGGCGGACAGAAGCCTGGGAGTGGAGCTGG CCGTGGGCACGCACCCCCCGCCTCAGTGTCATGGAGGAGGACCAGGCCTGTGCCATGGAGAGCCGGCGCT TTGAGGAGACCCGTGGCATGGAGGAGGAGCCCACCCACCTGCCTCTGGTTGTCTGCGTGGACAAACTCAC CAAGGTCTACAAGGACGACAAGAAGCTGGCCCTGAACAAGCTGAGCCTGAACCTCTACGAGAACCAGGTG GTCTCCTTCTTGGGCCACAACGGGGCGGGCAAGACCACCACCATGTCCATCCTGACCGGCCTGTTCCCTC CAACGTCGGGTTCCGCCACCATCTACGGGCACGACATCCGCACGGAGATGGATGAGATCCGCAAGAACCT GGGCATGTGCCCGCAGCACAATGTGCTCTTTGACCGGCTCACGGTGGAGGAACACCTCTGGTTCTACTCA CGGCTCAAGAGCATGGCTCAGGAGGAGATCCGCAGAGAGATGGACAAGATGATCGAGGACCTGGAGCTCT CCAACAAACGGCACTCACTGGTGCAGACATTGTCGGGTGGCATGAAGCGCAAGCTGTCCGTGGCCATCGC CTTCGTGGGCGGCTCTCGCGCCATCATCCTGGACGAGCCCACGGCGGGCGTGGACCCCTACGCGCGCCGC GCCATCTGGGACCTCATCCTGAAGTACAAGCCAGGCCGCACCATCCTTCTGTCCACCCACCACATGGATG AGGCTGACCTGCTTGGGGACCGCATTGCCATCATCTCCCATGGGAAGCTCAAGTGCTGCGGCTCCCCGCT CTTCCTCAAGGGCACCTATGGCGACGGGTACCGCCTCACGCTGGTCAAGCGGCCCGCCGAGCCGGGGGGC CCCCAAGAGCCAGGGCTGGCATCCAGCCCCCCAGGTCGGGCCCCGCTGAGCAGCTGCTCCGAGCTCCAGG TGTCCCAGTTCATCCGCAAGCATGTGGCCTCCTGCCTGCTGGTCTCAGACACAAGCACGGAGCTCTCCTA CATCCTGCCCAGCGAGGCCGCCAAGAAGGGGGCTTTCGAGCGCCTCTTCCAGCACCTGGAGCGCAGCCTG GATGCACTGCACCTCAGCAGCTTCGGGCTGATGGACACGACCCTGGAGGAAGTGTTCCTCAAGGTGTCGG AGGAGGATCAGTCGCTGGAGAACAGTGAGGCCGATGTGAAGGAGTCCAGGAAGGATGTGCTCCCTGGGGC GGAGGGCCCGGCGTCTGGGGAGGGTCACGCTGGCAATCTGGCCCGGTGCTCGGAGCTGACCCAGTCGCAG GCATCGCTGCAGTCGGCGTCATCTGTGGGCTCTGCCCGTGGCGACGAGGGAGCTGGCTACACCGACGTCT ATGGCGACTACCGCCCCCTCTTTGATAACCCACAGGACCCAGACAATGTCAGCCTGCAAGAGGTGGAGGC AGAGGCCCTGTCGAGGGTCGGCCAGGGCAGCCGCAAGCTGGACGGCGGGTGGCTGAAGGTGCGCCAGTTC CACGGGCTGCTGGTCAAACGCTTCCACTGCGCCCGCCGCAACTCCAAGGCACTCTTCTCCCAGATCTTGC TGCCAGCCTTCTTCGTCTGCGTGGCCATGACCGTGGCCCTGTCCGTCCCGGAGATTGGTGATCTGCCCCC GCTGGTCCTGTCACCTTCCCAGTACCACAACTACACCCAGCCCCGTGGCAATTTCATCCCCTACGCCAAC GAGGAGCGCCGCGAGTACCGGCTGCGGCTATCGCCCGACGCCAGCCCCCAGCAGCTCGTGAGCACGTTCC GGCTGCCGTCGGGGGTGGGTGCCACCTGCGTGCTCAAGTCTCCCGCCAACGGCTCGCTGGGGCCCACGTT GAACCTGAGCAGCGGGGAGTCGCGCCTGCTGGCGGCTCGGTTCTTCGACAGCATGTGTCTGGAGTCCTTC ACACAGGGGCTGCCACTGTCCAATTTCGTGCCACCCCCACCCTCGCCCGCCCCATCTGACTCGCCAGCGT CCCCGGATGAGGACCTGCAGGCCTGGAACGTCTCCCTGCCGCCCACCGCTGGGCCAGAAATGTGGACGTC GGCACCCTCCCTGCCGCGCCTGGTACGGGAGCCCGTCCGCTGCACCTGCTCTGCGCAGGGCACCGGCTTC TCCTGCCCCAGCAGTGTGGGCGGGCACCCGCCCCAGATGCGGGTGGTCACAGGCGACATCCTGACCGACA TCACCGGCCACAATGTCTCTGAGTACCTGCTCTTCACCTCCGACCGCTTCCGACTGCACCGGTATGGGGC CATCACCTTTGGAAACGTCCTGAAGTCCATCCCAGCCTCATTTGGCACCAGGGCCCCACCCATGGTGCGG AAGATCGCGGTGCGCAGGGCTGCCCAGGTTTTCTACAACAACAAGGGCTATCACAGCATGCCCACCTACC TCAACAGCCTCAACAACGCCATCCTGCGTGCCAACCTGCCCAAGAGCAAGGGCAACCCGGCGGCTTACGG CATCACCGTCACCAACCACCCCATGAATAAGACCAGCGCCAGCCTCTCCCTGGATTACCTGCTGCAGGGC ACGGATGTCGTCATCGCCATCTTCATCATCGTGGCCATGTCCTTCGTGCCGGCCAGCTTCGTTGTCTTCC TCGTGGCCGAGAAGTCCACCAAGGCCAAGCACCTGCAGTTTGTCAGCGGCTGCAACCCCATCATCTACTG GCTGGCGAACTACGTGTGGGACATGCTCAACTACCTGGTCCCCGCTACCTGCTGTGTCATCATCCTGTTT GTGTTCGACCTGCCGGCCTACACGTCGCCCACCAACTTCCCTGCCGTCCTCTCCCTCTTCCTGCTCTATG GGTGGTCCATCACGCCCATCATGTACCCGGCCTCCTTCTGGTTCGAGGTCCCCAGCTCCGCCTACGTGTT CCTCATTGTCATCAATCTCTTCATCGGCATCACCGCCACCGTGGCCACCTTCCTGCTACAGCTCTTCGAG CACGACAAGGACCTGAAGGTTGTCAACAGTTACCTGAAAAGCTGCTTCCTCATTTTCCCCAACTACAACC TGGGCCACGGGCTCATGGAGATGGCCTACAACGAGTACATCAACGAGTACTACGCCAAGATTGGCCAGTT TGACAAGATGAAGTCCCCGTTCGAGTGGGACATTGTCACCCGCGGACTGGTGGCCATGGCGGTTGAGGGC GTCGTGGGCTTCCTCCTGACCATCATGTGCCAGTACAACTTCCTGCGGCGGCCACAGCGCATGCCTGTGT CTACCAAGCCTGTGGAGGATGATGTGGACGTGGCCAGTGAGCGGCAGCGAGTGCTCCGGGGAGACGCCGA CAATGACATGGTCAAGATTGAGAACCTGACCAAGGTCTACAAGTCCCGGAAGATTGGCCGTATCCTGGCC GTTGACCGCCTGTGCCTGGGTGTGCGTCCTGGCGAGTGCTTCGGGCTCCTGGGCGTCAACGGTGCGGGCA AGACCAGCACCTTCAAGATGCTGACCGGCGACGAGAGCACGACGGGGGGCGAGGCCTTCGTCAATGGACA CAGCGTGCTGAAGGAGCTGCTCCAGGTGCAGCAGAGCCTCGGCTACTGCCCGCAGTGTGACGCGCTGTTC GACGAGCTCACGGCCCGGGAGCACCTGCAGCTGTACACGCGGCTGCGTGGGATCTCCTGGAAGGACGAGG CCCGGGTGGTGAAGTGGGCTCTGGAGAAGCTGGAGCTGACCAAGTACGCAGACAAGCCGGCTGGCACCTA CAGCGGCGGCAACAAGCGGAAGCTCTCCACGGCCATCGCCCTCATTGGGTACCCAGCCTTCATCTTCCTG GACGAGCCCACCACAGGCATGGACCCCAAGGCCCGGCGCTTCCTCTGGAACCTCATCCTTGACCTCATCA AGACAGGGCGTTCAGTGGTGCTGACATCACACAGCATGGAGGAGTGCGAGGCGCTGTGCACGCGGCTGGC CATCATGGTGAACGGTCGCCTGCGGTGCCTGGGCAGCATCCAGCACCTGAAGAACCGGTTTGGAGATGGC TACATGATCACGGTGCGGACCAAGAGCAGCCAGAGTGTGAAGGACGTGGTGCGGTTCTTCAACCGCAACT TCCCGGAAGCCATGCTCAAGGAGCGGCACCACACAAAGGTGCAGTACCAGCTCAAGTCGGAGCACATCTC GCTGGCCCAGGTGTTCAGCAAGATGGAGCAGGTGTCTGGCGTGCTGGGCATCGAGGACTACTCGGTCAGC CAGACCACACTGGACAATGTGTTCGTGAACTTTGCCAAGAAGCAGAGTGACAACCTGGAGCAGCAGGAGA CGGAGCCGCCATCCGCACTGCAGTCCCCTCTCGGCTGCTTGCTCAGCCTGCTCCGGCCCCGGTCTGCCCC CACGGAGCTCCGGGCACTTGTGGCAGACGAGCCCGAGGACCTGGACACGGAGGACGAGGGCCTCATCAGC TTCGAGGAGGAGCGGGCCCAGCTGTCCTTCAACACGGACACGCTCTGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA Protein Sequence (showhide) >RC216007 representing NM_212533 Red=Cloning site Green=Tags(s) MGRKTSRVQQGPPRSPACSAHGERSWGLEFPPFRWLLGIAGRTHLAALPPFQWVLAFEIFIPLVLFFILL GLRQKKPTISVKEVSFYTAAPLTSAGILPVMQSLCPDGQRDEFGFLQYANSTVTQLLERLDRVVEEGNLF DPARPSLGSELEALRQHLEALSAGPGTSGSHLDRSTVSSFSLDSVARNPQELWRFLTQNLSLPNSTAQAL LAARVDPPEVYHLLFGPSSALDSQSGLHKGQEPWSRLGGNPLFRMEELLLAPALLEQLTCTPGSGELGRI LTVPESQKGALQGYRDAVCSGQAAARARRFSGLSAELRNQLDVAKVSQQLGLDAPNGSDSSPQAPPPRRL QALLGDLLDAQKVLQDVDVLSALALLLPQGACTGRTPGPPASGAGGAANGTGAGAVMGPNATAEEGAPSA AALATPDTLQGQCSAFVQLWAGLQPILCGNNRTIEPEALRRGNMSSLGFTSKEQRNLGLLVHLMTSNPKI LYAPAGSEVDRVILKANETFAFVGNVTHYAQVWLNISAEIRSFLEQGRLQQHLRWLQQYVAELRLHPEAL NLSLDELPPALRQDNFSLPSGMALLQQLDTIDNAACGWIQFMSKVSVDIFKGFPDEESIVNYTLNQAYQD NVTVFASVIFQTRKDGSLPPHVHYKIRQNSSFTEKTNEIRRAYWRPGPNTGGRFYFLYGFVWIQDMMERA IIDTFVGHDVVEPGSYVQMFPYPCYTRDDFLFVIEHMMPLCMVISWVYSVAMTIQHIVAEKEHRLKEVMK TMGLNNAVHWVAWFITGFVQLSISVTALTAILKYGQVLMHSHVVIIWLFLAVYAVATIMFCFLVSVLYSK AKLASACGGIIYFLSYVPYMYVAIREEVAHDKITAFEKCIASLMSTTAFGLGSKYFALYEVAGVGIQWHT FSQSPVEGDDFNLLLAVTMLMVDAVVYGILTWYIEAVHPGMYGLPRPWYFPLQKSYWLGSGRTEAWEWSW PWARTPRLSVMEEDQACAMESRRFEETRGMEEEPTHLPLVVCVDKLTKVYKDDKKLALNKLSLNLYENQV VSFLGHNGAGKTTTMSILTGLFPPTSGSATIYGHDIRTEMDEIRKNLGMCPQHNVLFDRLTVEEHLWFYS RLKSMAQEEIRREMDKMIEDLELSNKRHSLVQTLSGGMKRKLSVAIAFVGGSRAIILDEPTAGVDPYARR AIWDLILKYKPGRTILLSTHHMDEADLLGDRIAIISHGKLKCCGSPLFLKGTYGDGYRLTLVKRPAEPGG PQEPGLASSPPGRAPLSSCSELQVSQFIRKHVASCLLVSDTSTELSYILPSEAAKKGAFERLFQHLERSL DALHLSSFGLMDTTLEEVFLKVSEEDQSLENSEADVKESRKDVLPGAEGPASGEGHAGNLARCSELTQSQ ASLQSASSVGSARGDEGAGYTDVYGDYRPLFDNPQDPDNVSLQEVEAEALSRVGQGSRKLDGGWLKVRQF HGLLVKRFHCARRNSKALFSQILLPAFFVCVAMTVALSVPEIGDLPPLVLSPSQYHNYTQPRGNFIPYAN EERREYRLRLSPDASPQQLVSTFRLPSGVGATCVLKSPANGSLGPTLNLSSGESRLLAARFFDSMCLESF TQGLPLSNFVPPPPSPAPSDSPASPDEDLQAWNVSLPPTAGPEMWTSAPSLPRLVREPVRCTCSAQGTGF SCPSSVGGHPPQMRVVTGDILTDITGHNVSEYLLFTSDRFRLHRYGAITFGNVLKSIPASFGTRAPPMVR KIAVRRAAQVFYNNKGYHSMPTYLNSLNNAILRANLPKSKGNPAAYGITVTNHPMNKTSASLSLDYLLQG TDVVIAIFIIVAMSFVPASFVVFLVAEKSTKAKHLQFVSGCNPIIYWLANYVWDMLNYLVPATCCVIILF VFDLPAYTSPTNFPAVLSLFLLYGWSITPIMYPASFWFEVPSSAYVFLIVINLFIGITATVATFLLQLFE HDKDLKVVNSYLKSCFLIFPNYNLGHGLMEMAYNEYINEYYAKIGQFDKMKSPFEWDIVTRGLVAMAVEG VVGFLLTIMCQYNFLRRPQRMPVSTKPVEDDVDVASERQRVLRGDADNDMVKIENLTKVYKSRKIGRILA VDRLCLGVRPGECFGLLGVNGAGKTSTFKMLTGDESTTGGEAFVNGHSVLKELLQVQQSLGYCPQCDALF DELTAREHLQLYTRLRGISWKDEARVVKWALEKLELTKYADKPAGTYSGGNKRKLSTAIALIGYPAFIFL DEPTTGMDPKARRFLWNLILDLIKTGRSVVLTSHSMEECEALCTRLAIMVNGRLRCLGSIQHLKNRFGDG YMITVRTKSSQSVKDVVRFFNRNFPEAMLKERHHTKVQYQLKSEHISLAQVFSKMEQVSGVLGIEDYSVS QTTLDNVFVNFAKKQSDNLEQQETEPPSALQSPLGCLLSLLRPRSAPTELRALVADEPEDLDTEDEGLIS FEEERAQLSFNTDTLC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Chromatograms	CHROMATOGRAMS Sequencher program is needed, download here.
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_212533
ORF Size	7398 bp
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_212533.1, NP_997698.1
RefSeq Size	8164 bp
RefSeq ORF	7401 bp
Locus ID	20
UniProt ID	Q9BZC7
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ABC transporters, Lysosome
MW	272.8 kDa
Gene Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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