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CRMP2 (DPYSL2) (NM_001386) Human Tagged ORF Clone
CAT＃: RC209080
- TrueORF®
DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2
ORF Plasmid: tGFP
"NM_001386" in other vectors (6)
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CNY 6,384.00
| Cited in 1 publication. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC209080 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCTTATCAGGGGAAGAAAAATATTCCACGCATCACGAGCGATCGTCTTCTGATCAAAGGAGGTAAAA TTGTTAATGATGACCAGTCGTTCTATGCAGACATATACATGGAAGATGGGTTGATCAAGCAAATAGGAGA AAATCTGATTGTGCCAGGAGGAGTGAAGACCATCGAGGCCCACTCCCGGATGGTGATCCCCGGAGGAATT GACGTCCACACTCGTTTCCAGATGCCTGATCAGGGAATGACGTCTGCTGATGATTTCTTCCAAGGAACCA AGGCGGCCCTGGCTGGGGGAACCACTATGATCATTGACCACGTTGTTCCTGAGCCTGGGACAAGCCTGCT CGCTGCCTTTGACCAGTGGAGGGAATGGGCCGACAGCAAGTCCTGCTGTGACTACTCTCTGCATGTGGAC ATCAGCGAGTGGCATAAGGGCATCCAGGAGGAGATGGAAGCGCTTGTGAAGGATCACGGGGTAAATTCCT TCCTCGTGTACATGGCTTTCAAAGATCGCTTCCAGCTAACGGATTGCCAGATTTATGAAGTACTGAGTGT GATCCGGGATATTGGCGCCATAGCCCAAGTCCACGCAGAAAATGGCGACATCATTGCAGAGGAGCAGCAG AGGATCCTGGATCTGGGCATCACGGGCCCCGAGGGACATGTGCTGAGCCGACCTGAGGAGGTCGAGGCCG AAGCCGTGAATCGTGCCATCACCATCGCCAACCAGACCAACTGCCCGCTGTATATCACCAAGGTGATGAG CAAAAGCTCTGCTGAGGTCATCGCCCAGGCACGGAAGAAGGGAACTGTGGTGTATGGCGAGCCCATCACT GCCAGCTTGGGAACGGACGGCTCCCATTACTGGAGCAAGAACTGGGCCAAGGCTGCTGCCTTTGTCACCT CCCCACCCTTGAGCCCTGATCCAACCACTCCAGACTTTCTCAACTCCTTGCTGTCCTGTGGAGACCTCCA GGTCACGGGCAGTGCCCATTGCACGTTTAACACTGCCCAGAAGGCTGTAGGAAAGGACAACTTCACCCTG ATTCCGGAGGGCACCAATGGCACTGAGGAGCGGATGTCCGTCATCTGGGACAAGGCTGTGGTCACTGGGA AGATGGATGAGAACCAGTTTGTGGCTGTGACCAGCACCAATGCAGCCAAAGTCTTCAACCTTTACCCCCG GAAAGGCCGCATTGCTGTGGGATCCGATGCCGACCTGGTCATCTGGGACCCCGACAGCGTTAAAACCATC TCTGCCAAGACACACAACAGCTCTCTCGAGTACAACATCTTTGAAGGCATGGAGTGCCGCGGCTCCCCAC TGGTAGTCATCAGCCAGGGGAAGATTGTCCTGGAGGACGGCACCCTGCATGTCACCGAAGGCTCTGGACG CTACATTCCCCGGAAGCCCTTCCCTGATTTTGTTTACAAGCGTATCAAGGCAAGGAGCAGGCTGGCTGAG CTGAGAGGGGTTCCTCGTGGCCTGTATGACGGACCCGTGTGTGAAGTGTCTGTGACGCCCAAGACAGTCA CTCCAGCCTCCTCGGCCAAGACGTCTCCTGCCAAGCAGCAGGCCCCACCTGTCCGGAACCTGCACCAGTC TGGATTCAGTTTGTCTGGTGCTCAGATTGATGACAACATTCCCCGCCGCACCACCCAGCGTATCGTGGCG CCCCCCGGTGGCCGTGCCAACATCACCAGCCTGGGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC209080 protein sequence
Red=Cloning site Green=Tags(s) MSYQGKKNIPRITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGI DVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVD ISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQ RILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPIT ASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTL IPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTI SAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAE LRGVPRGLYDGPVCEVSVTPKTVTPASSAKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVA PPGGRANITSLG TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001386 |
| ORF Size | 1716 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001386.6 |
| RefSeq Size | 4638 bp |
| RefSeq ORF | 1719 bp |
| Locus ID | 1808 |
| UniProt ID | Q16555 |
| Domains | Amidohydro_1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Axon guidance |
| MW | 62.3 kDa |
| Gene Summary | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
PlexinA2 and CRMP2 Signaling Complex is Activated by Nogo-A-Liganded NgR1 to Restrict Corticospinal Axon Sprouting after Trauma
,Sekine, Y;Algarate, PT;Cafferty, WBJ;Strittmatter, SM;,
J. Neurosci.
,PubMed ID 30804090
[CRMP2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209080L1 | Lenti-ORF clone of DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 8,784.00 |
|
| RC209080L2 | Lenti-ORF clone of DPYSL2 (mGFP-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RC209080L3 | Lenti-ORF clone of DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RC209080L4 | Lenti-ORF clone of DPYSL2 (mGFP-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RG209080 | DPYSL2 (tGFP-tagged) - Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 5,040.00 |
|
| SC126729 | DPYSL2 (untagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,400.00 |
