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NKG2A (KLRC1) (NM_002259) Human Tagged Lenti ORF Clone
CAT＃: RC208585L1
- LentiORF®
Lenti ORF clone of Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1, Myc-DDK-tagged
"NM_002259" in other vectors (7)
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CNY 5,890.00
Product images
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CD159A; NKG2; NKG2A |
| Vector | pLenti-C-Myc-DDK |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC208585).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_002259 |
| ORF Size | 699 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002259.3, NP_002250.1 |
| RefSeq Size | 1443 bp |
| RefSeq ORF | 702 bp |
| Locus ID | 3821 |
| UniProt ID | P26715 |
| Protein Families | Transmembrane |
| Protein Pathways | Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity |
| MW | 26.3 kDa |
| Gene Summary | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jan 2015] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208585 | KLRC1 (Myc-DDK-tagged)-Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1 |
CNY 2,400.00 |
|
| RC208585L2 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RC208585L3 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC208585L4 | Lenti ORF clone of Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG208585 | KLRC1 (tGFP-tagged) - Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1 |
CNY 4,000.00 |
|
| SC303158 | KLRC1 (untagged)-Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1 |
CNY 3,990.00 |
|
| SC320997 | KLRC1 (untagged)-Human killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 1 |
CNY 2,400.00 |
