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ARHGEF6 (NM_004840) Human Tagged ORF Clone
CAT＃: RC208074
- TrueORF®
ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6)
ORF Plasmid: tGFP
"NM_004840" in other vectors (6)
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CNY 5,688.00
CNY 5,800.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | alpha-PIX; alphaPIX; Cool-2; COOL2; MRX46; PIXA |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC208074 representing NM_004840
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAATCCAGAAGAACAAATCGTGACATGGCTTATATCTTTGGGAGTTTTAGAGTCCCCTAAAAAGACCA TCTGTGATCCGGAGGAGTTTTTAAAGTCCTCGCTGAAAAATGGGGTAGTTCTGTGCAAACTGATCAACAG ACTCATGCCTGGCTCTGTGGAAAAGTTTTGTCTGGATCCCCAAACTGAAGCTGACTGCATCAACAACATC AATGACTTCCTGAAAGGATGTGCAACCCTCCAAGTGGAAATATTTGATCCTGATGACCTTTATTCAGGGG TCAATTTCTCCAAGGTACTGAGTACTCTTTTAGCTGTCAACAAAGCAACAGAAGATCAGCTATCAGAAAG ACCATGTGGACGTTCCTCTTCTCTTAGTGCTGCTAATACTTCTCAGACAAACCCACAGGGAGCAGTTTCT AGCACAGTTTCAGGGCTGCAAAGGCAGTCAAAGACAGTGGAGATGACGGAAAATGGAAGTCATCAGTTGA TAGTAAAAGCAAGATTCAACTTTAAGCAGACTAATGAGGATGAACTGTCAGTTTGTAAGGGGGACATCAT TTACGTCACACGAGTTGAAGAAGGAGGCTGGTGGGAAGGCACATTAAATGGGAGAACAGGCTGGTTCCCC AGTAATTATGTCCGTGAAATTAAATCCAGTGAGAGACCTCTCTCCCCAAAAGCCGTCAAAGGATTTGAAA CTGCTCCACTTACCAAGAATTATTATACTGTGGTGTTACAGAACATCCTGGACACTGAAAAAGAATATGC TAAAGAACTTCAGTCTCTTCTTGTTACTTACTTAAGACCCCTGCAGTCCAATAACAATCTGAGTACTGTG GAGGTTACATCTTTACTGGGAAACTTCGAGGAAGTATGCACATTTCAACAGACACTCTGCCAAGCCTTGG AAGAATGTTCAAAGTTTCCAGAAAACCAGCACAAAGTAGGAGGTTGTCTACTGAGTCTCATGCCTCATTT TAAATCTATGTATCTGGCTTACTGTGCAAACCATCCTTCAGCTGTAAATGTGCTCACTCAGCACAGTGAT GAGTTGGAACAATTCATGGAAAATCAAGGTGCATCGAGCCCAGGTATCCTCATTTTAACAACAAACCTCA GCAAACCATTCATGCGACTGGAGAAATATGTTACTCTCTTGCAAGAGTTAGAACGGCATATGGAGGATAC TCATCCAGATCATCAGGATATTCTGAAAGCAATCGTAGCATTCAAAACTCTCATGGGGCAATGTCAAGAT CTGAGGAAGAGAAAACAGCTGGAGTTACAGATACTGTCCGAACCTATTCAGGCATGGGAAGGAGAAGATA TTAAAAACTTGGGAAATGTGATTTTTATGTCACAAGTAATGGTGCAGTATGGAGCATGTGAGGAAAAAGA GGAGCGGTACCTTATGTTATTTTCAAATGTCCTGATAATGTTATCTGCAAGTCCTCGGATGAGTGGCTTT ATCTATCAGGGAAAAATACCAATAGCAGGAACGGTGGTGACTAGATTAGATGAAATTGAAGGGAATGACT GCACATTTGAAATCACTGGTAACACAGTGGAGAGAATTGTGGTCCATTGTAACAACAACCAGGACTTCCA GGAATGGTTGGAGCAGCTGAACAGACTGATCAGAGGACCTGCCTCTTGCAGTTCATTATCCAAAACCTCA TCGTCATCATGTAGTGCTCATTCTTCTTTTAGCTCTACCGGACAGCCCCGAGGACCCTTGGAGCCTCCTC AAATTATAAAACCGTGGAGTTTAAGTTGTCTACGACCTGCACCTCCACTTAGACCATCAGCAGCACTAGG TTATAAAGAGAGGATGTCTTATATCTTAAAGGAGTCTAGTAAAAGCCCTAAAACGATGAAGAAATTTCTT CATAAAAGGAAGACTGAGAGAAAACCATCGGAGGAGGAATATGTGATTAGGAAAAGTACAGCTGCTCTGG AAGAGGATGCTCAAATCCTTAAAGTGATCGAAGCCTACTGCACCAGCGCAAATTTTCAACAAGGCCATGG CTCAAGTACTCGAAAAGATTCCATTCCACAAGTCCTACTCCCTGAGGAAGAGAAACTCATCATTGAAGAA ACCAGAAGCAACGGCCAGACCATCATGGAAGAAAAGAGCCTTGTTGATACTGTTTACGCCTTGAAGGACG AGGTCAGAGAACTGAAGCAGGAAAATAAAAGAATGAAGCAATGCCTGGAAGAAGAACTGAAATCAAGAAG GGACCTAGAAAAGCTGGTGCGGAGGCTTTTGAAGCAAACAGATGAGTGTATTCGAGGCGAGTCCAGTAGC AAGACCTCAATTCTTCCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC208074 representing NM_004840
Red=Cloning site Green=Tags(s) MNPEEQIVTWLISLGVLESPKKTICDPEEFLKSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNI NDFLKGCATLQVEIFDPDDLYSGVNFSKVLSTLLAVNKATEDQLSERPCGRSSSLSAANTSQTNPQGAVS STVSGLQRQSKTVEMTENGSHQLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNGRTGWFP SNYVREIKSSERPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTV EVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFKSMYLAYCANHPSAVNVLTQHSD ELEQFMENQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDHQDILKAIVAFKTLMGQCQD LRKRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGF IYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRGPASCSSLSKTS SSSCSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFL HKRKTERKPSEEEYVIRKSTAALEEDAQILKVIEAYCTSANFQQGHGSSTRKDSIPQVLLPEEEKLIIEE TRSNGQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSS KTSILP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004840 |
| ORF Size | 2328 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004840.3 |
| RefSeq Size | 5282 bp |
| RefSeq ORF | 2331 bp |
| Locus ID | 9459 |
| UniProt ID | Q15052 |
| Domains | RhoGEF, SH3, CH, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Pancreatic cancer, Regulation of actin cytoskeleton |
| MW | 87.3 kDa |
| Gene Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208074L1 | Lenti-ORF clone of ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 7,700.00 |
|
| RC208074L2 | Lenti-ORF clone of ARHGEF6 (mGFP-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 7,700.00 |
|
| RC208074L3 | Lenti-ORF clone of ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 7,700.00 |
|
| RC208074L4 | Lenti-ORF clone of ARHGEF6 (mGFP-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 7,700.00 |
|
| RG208074 | ARHGEF6 (tGFP-tagged) - Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 6,370.00 |
|
| SC100230 | ARHGEF6 (untagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CNY 5,688.00 |
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