United States
Germany
Japan
United Kingdom
China
CD42b (GP1BA) (NM_000173) Human Tagged Lenti ORF Clone
CAT＃: RC206598L3
- LentiORF®
Lenti ORF clone of Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA), Myc-DDK-tagged
"NM_000173" in other vectors (7)
Need custom modification / cloning service?
Get a free quote
CNY 5,890.00
Product images
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; GPIbA; GPIbalpha; VWDP |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC206598).
|
| Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
| ACCN | NM_000173 |
| ORF Size | 1878 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000173.4, NP_000164.3 |
| RefSeq Size | 2501 bp |
| RefSeq ORF | 1959 bp |
| Locus ID | 2811 |
| UniProt ID | P07359 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
| MW | 69 kDa |
| Gene Summary | Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy. [provided by RefSeq, Oct 2013] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206598 | GP1BA (Myc-DDK-tagged)-Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA) |
CNY 4,664.00 |
|
| RC206598L1 | Lenti ORF clone of Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206598L2 | Lenti ORF clone of Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA), mGFP tagged |
CNY 5,890.00 |
|
| RC206598L4 | Lenti ORF clone of Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA), mGFP tagged |
CNY 5,890.00 |
|
| RG206598 | GP1BA (tGFP-tagged) - Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA) |
CNY 4,370.00 |
|
| SC122550 | GP1BA (untagged)-Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA) |
CNY 4,672.00 |
|
| SC318092 | GP1BA (untagged)-Human glycoprotein Ib (platelet), alpha polypeptide (GP1BA) |
CNY 10,450.00 |
