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DUSP3 (NM_004090) Human Tagged Lenti ORF Clone
CAT＃: RC201119L3
- LentiORF®
Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), Myc-DDK-tagged
"NM_004090" in other vectors (6)
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CNY 5,890.00
Product images
CNY 1,999.00
CNY 2,700.00
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | VHR |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC201119).
|
| Restriction Sites | SgfI-RsrII Cloning Scheme for this gene |
| ACCN | NM_004090 |
| ORF Size | 555 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004090.2 |
| RefSeq Size | 4139 bp |
| RefSeq ORF | 558 bp |
| Locus ID | 1845 |
| UniProt ID | P51452 |
| Domains | DSPc |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
| MW | 20.5 kDa |
| Gene Summary | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201119 | DUSP3 (Myc-DDK-tagged)-Human dual specificity phosphatase 3 (DUSP3) |
CNY 2,400.00 |
|
| RC201119L1 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC201119L2 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), mGFP tagged |
CNY 5,890.00 |
|
| RC201119L4 | Lenti ORF clone of Human dual specificity phosphatase 3 (DUSP3), mGFP tagged |
CNY 5,890.00 |
|
| RG201119 | DUSP3 (tGFP-tagged) - Human dual specificity phosphatase 3 (DUSP3) |
CNY 4,000.00 |
|
| SC108794 | DUSP3 (untagged)-Human dual specificity phosphatase 3 (DUSP3) |
CNY 2,400.00 |
