Sorbs2 (NM_001205219) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	2010203O03Rik; 9430041O17Rik; A530071H08; Argbp2; mKIAA0777; nArgBP2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC229480 representing NM_001205219 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAATACAGATAGCGGTGGGTGTGCTCGCAAACGTGCCGCCATGTCTGTTACGTTAACATCTGTGAAGA GAGTTCAAAGTTCTCCAAACCTATTGGCTGCAGGGCGTGAGTCTCAGTCTCCAGATTCAGCTTGGAGATC TTACAATGATCGGAATCCAGAGACACTGAACGGAGATGCCACATATTCCTCTCTTGCAGCAAAAGGTTTT AGAAGCGTTCGGCCAAACCTGCAAGACAAAAGATCACCGACCCAGAGCCAGATCACTATCAATGGCAACT CTGGTGGCGCCGTGAGTCCAGTGAGTTACTATCAGAGGCCATTCTCCCCTTCTGCATACTCCCTCCCAGC CTCGCTGAACTCCAGCATTATCATGCAGCACGGCAGGTCTCTTGATTCTGCAGAGACATATTCCCAGCAT GCCCAGTCCCTGGATGGCACCATGGGAAGCTCCATCCCGCTCTATAGATCCTCCGAGGAAGAGAAGAGGG TCACGGTCATCAAAGCCCCGCATTACCCAGGGATCGGCCCTGTGGATGAGTCTGGAATCCCCACAGCCAT TAGGACGACTGTCGACAGGCCAAAGGACTGGTACAAGACAATGTTCAAGCAAATCCACATGGTACACAAG CCGGATGAGGACACAGACATGTATAATACTCCTTACACATACAACGCAGGTCTGTACAACTCGCCCTACA GTGCTCAGTCCCACCCGGCTGCGAAGACTCAGACCTACAGACCTCTTTCGAAAAGCCACTCAGACAATGG CACCGATGCGTTTAAGGAGGTGCCCTCCCCAGTGCCTCCCCCACACGTCCCACCACGACCAAGAGATCAG TCTTCAACACTAAAGCATGACTGGGACCCTCCAGACAGAAAGGTGGACACCAGGAAATTTCGATCGGAGC CAAGGAGTATTTTTGAATATGAGCCTGGGAAGTCGTCCATTCTGCAGCACGAAAGACCCCCTCCTAAAAA GGCTCTGGATTATGTTCAAGATCATTCTTCCGGTGTGTCCAACGAGGTCTCCATCTATCAGTCCTCCATA GACAGAAGCCTGGAAAGACCCAGCAGCTCTGCAAGCATGGCCGGTGACTTTAGGAAACGGAGGAAGAGCG AACCTGCAGTGGGCCCACTCCGGGGCTTGGGGGATCAGAGTTCAAGCAGGACCAGCCCTGGCCGGGCGGA CCTCCCAGGATCAAGTTCCACCTTTACGAAGTCTTTCATTAGCTCTTCTCCTTCCTCTCCCTCGAGAGCA CAAGGTGGGGATGATAGCAAAATGTGTCCGCCCCTTTGCAGTTACTCGGGGCTCAATGGCACCCCCTCTG GTGAGTTAGAGTGCTGCAACGCTTACAGACAACATTTGGACGTCCCCGGGGACTCGCAAAGGGCCATCAC TTTCAAGAATGGCTGGCAAATGGCCCGGCAAAATGCAGAGATCTGGAGTAGCACTGAAGAGACCGTTTCC CCCAAAATCAAATCACGTAGCTGCGATGATCTCCTGAATGACGACTGCGACAGCTTCCCAGACCCTAAAA CCAAGTCAGAGAGTATGGGTTCTCTGTTATGTGAAGAAGACTCCAAAGAGAGCTGCCCCATGACATGGGC GTCCCCCTACATCCAGGAAGTGTGCGGGAACAGCAGATCTAGGCTCAAACACAGGTCAGCCCATAATGCC CCAGGCTTCCTCAAAATGTACAAGAAAATGCATCGCATCAACCGCAAGGACTTGATGAATTCAGAGGTCA TTTGCTCGGTGAAATCCAGGATCCTGCAGTACGAGAAGGAGCAACAGCACAGGGGGCTGCTGCACGGATG GAGCCAGTCTTCCACCGAGGAGGTGCCCAGGGACGTGGTGCCCACTCGCATTTCGGAATTTGAAAAGCTG ATTCAGAAGTCGAAGTCTATGCCCAATCTAGGAGATGAAATGTTATCTCCTATAACCCTAGAACCCCCAC AAAATGGTTTGTGTCCCAAGAGGCGATTTTCTATCGAGTCTCTGCTGGAGGAAGAAACTCAGGTTCGTCA CCCTTCTCAGGGTCAGCGAAGCTGCAAGTCTAACACCCTGGTGCCCATCCACATCGAGGTCACCAGCGAC GAGCAACCTAGAACACACATGGAGTTTTCCGACAGTGACCAAGATGGGGTTGTGTCCGACCACAGCGACT ACGTTCACGTCGAAGGGTCGTCCTTTTGTAGTGAAAGTGACTTTGACCACTTTTCATTCACATCCTCTGA AAGCTTCTACGGATCGAGCCATCACCACCACCATCACCATCACCATCACCGACACCTCATCAGCTCCTGC AAAGGCCGATGCCCGGCTTCTTACACTCGATTTACCACAATGCTAAAACATGAAAGAGCTAAGCATGAAA ACATGGACCGACCCAGAAGGCAAGAAATGGATCCTGGCCTGTCTAAGCTTGCATTTCTAGTCAGCCCTGT GCCTTTCCGAAGGAAAAAAATCCTGACTCCCCAAAAACAGACTGAAAAGGCAAAATGCAAAGCCTCAGTA GTTGAAGCTCTGGACTCTGCCCTGAAAGACATTTGCGACCAAATAAAAGCCGAAAAGCGGAGGGGAAGCT TGCCAGACAACAGCATCCTGCACAGGCTTATCAGTGAACTGCTGCCACAGATTCCTGAAAGGAATTCATC TCTTCATGCTCTCAAAAGGAGCCCCATGCACCAGCCTTTCCACCCACTGCCTCCAGATGGTGCTAGTCAT TGTCCCCTGTACCAAAATGATTGTGGGAGAATGCCTCACAGTGCCTCTTTCCCTGACGTGGACACAACCA GCAACTACCACGCACAGGACTATGGGAGTGCACTGAGCCTCCAAGATCACGAGTCCCCTAGAAGTTACTC ATCTACTCTGACTGACTTGGGCAGAAGTGCATCACGGGAACGAAGGGGAACTCCAGAAAAAGAGAAATTG CCTGCAAAAGCTGTCTATGATTTCAAAGCTCAGACATCTAAGGAGCTGTCATTTAAGAAAGGAGACACTG TCTACATCCTCAGGAAAATTGACCAAAACTGGTATGAGGGGGAACACCACGGCAGAGTGGGCATTTTCCC AATCTCATACGTAGAGAAACTAACACCCCCGGAAAAAGCGCAGCCCGCAAGACCACCACCCCCAGTCCAG CCCGGAGAGATTGGAGAAGCCATAGCCAAGTACAACTTCAATGCAGACACAAATGTGGAACTCTCCCTGC GAAAGGGCGACAGGATTATTCTTCTTAAAAGAGTTGACCAAAACTGGTACGAAGGTAAAATCCCAGGAAC CAACAGACAAGGCATCTTCCCCGTGTCCTATGTCGAGGTTGTCAAGAGGAACGCAAAAGGTGCTGAGGAC TACCCAGACCCTCCTCTGCCCCACAGCTACTCCAGTGACAGAATTTACACCCTAAGCTCCAATAAGCCAC AGCGTCCTGGGTTCTCTCATGAAAACATTCAAGGTGGGGGAGAACCGTTTCAGGCTCTGTATAACTATAC TCCTAGGAACGAAGATGAGCTGGAACTCAGAGAAAGTGATGTCGTTGATGTCATGGAAAAGTGTGACGAC GGATGGTTTGTGGGAACTTCAAGAAGAACCAAATTCTTTGGTACTTTTCCCGGAAACTATGTCAAAAGGC TGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001205219
Insert Size	3645 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001205219.1, NP_001192148.1
RefSeq Size	6094 bp
RefSeq ORF	3645 bp
Locus ID	234214
Gene Summary	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

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