Catalase (CAT) (NM_001752) Human 3' UTR Clone

Specifications

Product Data
Product Name	Catalase (CAT) (NM_001752) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_001752
Insert Size	644 bp
Sequence Data	Insert Sequence (showhide) >SC208265 3' UTR clone of NM_001752 The sequence shown below is from the reference sequence of NM_001752. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GGAGAAGGCAAATCTGTGAGGCCGGGGCCCTGCACCTGTGCAGCGAAGCTTAGCGTTCATCCGTGTAACC CGCTCATCACTGGATGAAGATTCTCCTGTGCTAGATGTGCAAATGCAAGCTAGTGGCTTCAAAATAGAGA ATCCCACTTTCTATAGCAGATTGTGTAACAATTTTAATGCTATTTCCCCAGGGGAAAATGAAGGTTAGGA TTTAACAGTCATTTAAAAAAAAAATTTGTTTTGACGGATGATTGGATTATTCATTTAAAATGATTAGAAG GCAAGTTTCTAGCTAGAAATATGATTTTATTTGACAAAATTTGTTGAAATTATGTATGTTTACATATCAC CTCATGGCCTATTATATTAAAATATGGCTATAAATATATAAAAAGAAAAGATAAAGATGATCTACTCAGA AATTTTTATTTTTCTAAGGTTCTCATAGGAAAAGTACATTTAATACAGCAGTGTCATCAGAAGATAACTT GAGCACCGTCATGGCTTAATGTTTATTCCTGATAATAATTGATCAAATTCATTTTTTTCACTGGAGTTAC ATTAATGTTAATTCAGCACTGATTTCACAACAGATCAATTTGTAATTGCTTACATTTTTACAATAAATAA TCTGTACGTAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001752.3
Summary	This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
Locus ID	847

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