PCK1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	WB 1:5000~20000, IHC 1:150, ELISA 1:100-1:2000
Reactivity	Human, Rat, Monkey, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	DNA immunization. This antibody is specific for the Middle Region of the target protein.
Formulation	20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration	1.05mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	phosphoenolpyruvate carboxykinase 1
Database Link	NP_002582 Entrez Gene 18534 MouseEntrez Gene 362282 RatEntrez Gene 696207 MonkeyEntrez Gene 5105 Human UniProt ID P35558
Background	Major sites of expression of PEP Carboxylase are liver, kidney and adipocytes. PEP carboxylase, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. A mitochondrial isozyme of the encoded protein has also been characterized.
Synonyms	PEPCK-C; PEPCK1; PEPCKC
Note	This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Adipocytokine signaling pathway, Citrate cycle (TCA cycle), Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, PPAR signaling pathway, Pyruvate metabolism

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