CD5 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI6F7]

CAT#: TA501334AM

Anti-CD5 mouse monoclonal antibody, clone OTI6F7 (formerly 6F7), Biotinylated

Conjugation: Unconjugated Biotin HRP



  View other "OTI6F7" antibodies (5)

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CNY 3,990.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Clone Name OTI6F7
Applications FC, IHC, WB
Recommend Dilution WB 1:500~2000, FLOW 1:100
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human CD5 (NP_055022) produced in HEK293T cell.
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Biotin
Storage Condition Store at -20°C as received.
Predicted Protein Size 54.4 kDa
Gene Name CD5 molecule
Background CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2).
Synonyms LEU1; T1
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Hematopoietic cell lineage
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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