MTOR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1/500-1/1000
Reactivity	Human, Mouse, Pig
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human Phospho-mTOR (S2448) (Phosphorylated)
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	289kDa
Gene Name	mechanistic target of rapamycin
Database Link	Entrez Gene 2475 Human UniProt ID P42345
Background	Swiss-Prot Acc.P42345.An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Synonyms	FLJ44809; FRAP; FRAP1; FRAP2; KIAA1303; RAFT1; RAPT1; RAPTOR; RPTOR
Reference Data

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