CD147 (BSG) Rabbit Polyclonal Antibody

CAT#: TA354245

Rabbit anti CD147/EMMPRIN Polyclonal Antibody



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CNY 4,675.00


货期*
5周

规格
    • 100 ug

Product images

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Specifications

Product Data
Recommend Dilution WB 0.1-1 µg/ml ELISA N/A IP N/A IHC 2-10 µg/ml FC Not tested
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of full length of human CD147.
Formulation This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 27 kDa
Gene Name basigin (Ok blood group)
Background CD147 or EMMPRIN (extracellular matrix metalloproteinase inducer) is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. This protein is also a member of the immunoglobulin super-family, it is a 58kDa protein with two immunoglobulin domains that was originally purified from the plasma membrane of the human LX-1 lung carcinoma cell line. CD147 has been localized on the outer surface of tumor cells, where it interacts withfibroblasts to stimulate the expression of matrix metalloproteinases (MMPs). CD147 inhibition has been proposed as a novel strategy in the prevention of cancer invasion and metastasis.
Synonyms 5F7; CD147; EMMPRIN; OK; TCSF
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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