PSMB8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: 231 and A431 cells, Mouse liver and Human placenta tissue, Jurkat and Raji cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PSMB8
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	30 kDa
Gene Name	proteasome subunit beta 8
Database Link	NP_683720 Entrez Gene 16913 MouseEntrez Gene 5696 Human UniProt ID P28062
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
Synonyms	ALDD; D6S216; D6S216E; JMP; LMP7; NKJO; PSMB5i; RING10
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Proteasome

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