TRIF (TICAM1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, Immunoblotting, IP, Simple Western, WB
Recommend Dilution	Knockdown Validated, Immunocytochemistry/ Immunofluorescence: 1:10-1:100, Simple Western: 1:100, Immunohistochemistry-Paraffin: 1:200, Western Blot: 1 - 2 ug/ml, Immunoprecipitation, Immunoblotting, Immunohistochemistry: 1:200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	This antibody was developed against a synthetic peptide corresponding to amino acids 143-158 of mouse TRIF (NP_778154).
Formulation	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration	lot specific
Purification	Whole antisera
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	76 kDa
Gene Name	toll like receptor adaptor molecule 1
Database Link	NP_891549 Entrez Gene 106759 MouseEntrez Gene 363328 RatEntrez Gene 148022 Human UniProt ID Q8IUC6
Background	TICAM (Toll-interleukin 1 receptor domain (TIR)-containing adaptor molecule-1) or TRIF (Toll/IL-1 receptor domain-containing adapter inducing IFN-beta) plays an essential role in the MyD88-independent signaling of TLR3.
Synonyms	IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF
Note	The ~70 kD band detected by this antibody in western blot, corresponding to TRIF protein, is blocked by the immunizing peptide.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Toll-like receptor signaling pathway

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