H2BC21 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB 1:500 - 1:2000
Reactivity	Human, Mouse, Rat, Other (Wide Range)
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human HIST2H2BE
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	126
Gene Name	histone cluster 2, H2be
Database Link	NP_003519 Entrez Gene 319190 MouseEntrez Gene 295274 RatEntrez Gene 8349 Human UniProt ID Q16778
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Synonyms	GL105; H2B; H2B.1; H2BFQ; H2BGL105; H2BQ
Reference Data
Protein Pathways	Systemic lupus erythematosus

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