PPP2R4 (PTPA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF
Recommend Dilution	WB 1:500 - 1:2000, IHC 1:50- 1:200, IF 1:50- 1:200
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human PPP2R4
Formulation	Store at -20°C (regular) and -80°C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	protein phosphatase 2 phosphatase activator
Database Link	NP_821067 Entrez Gene 110854 MouseEntrez Gene 5524 Human UniProt ID Q15257
Background	Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	PP2A; PR53; PTPA
Reference Data
Protein Families	Druggable Genome, Phosphatase

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