Cpn10 (HSPE1) Rabbit Polyclonal Antibody [Clone ID: N/A]

Specifications

Product Data
Clone Name	N/A
Applications	IHC, WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat, Bovine, Canine, Guinea Pig, Pig, Rabbit, Sheep, Xenopus
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human Cpn10 peptide AA 91-101
Formulation	PBS pH 7.3, 0.02% sodium azide
Concentration	lot specific
Purification	Protein A Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	heat shock protein family E (Hsp10) member 1
Database Link	NP_002148 Entrez Gene 15528 MouseEntrez Gene 25462 RatEntrez Gene 3336 Human UniProt ID P61604
Background	Chaperonin 10, otherwise known as Cpn10, (groES in E.coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s). Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process . Cpn10 has been located in human platelets, but is also present in human maternal serum . It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy .
Synonyms	CPN10; EPF; GROES; HSP10
Note	Detects ~ 10kDa.
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency

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