Heme oxygenase 2 (HMOX2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: HepG2 cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 82-316 amino acids of human heme oxygenase (decycling) 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	36 kDa
Gene Name	heme oxygenase 2
Database Link	NP_001120676 Entrez Gene 15369 MouseEntrez Gene 79239 RatEntrez Gene 3163 Human UniProt ID P30519
Background	Heme oxygenase; an essential enzyme in heme catabolism; cleaves heme to form biliverdin; which is subsequently converted to bilirubin by biliverdin reductase; and carbon monoxide; a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes; an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.?
Synonyms	HO-2
Reference Data
Protein Families	Transmembrane
Protein Pathways	Porphyrin and chlorophyll metabolism

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