AGA Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Mouse kidney tissue, Mouse testis tissue, Mouse lung tissue, Hela cell, Mouse fetal liver tissue, MCF7 cell, 293T cell lysates IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 206-346 amino acids of human aspartylglucosaminidase
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	37 kDa
Gene Name	aspartylglucosaminidase
Database Link	NP_000018 Entrez Gene 11593 MouseEntrez Gene 290923 RatEntrez Gene 175 Human UniProt ID P20933
Background	Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified.?
Synonyms	AGU; ASRG; GA
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Lysosome, Other glycan degradation

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