Heparanase 1 (HPSE) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:2000-5000, WB: 1:500-2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a C terminal 250 amino acids of human heparanase
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	61 kDa
Gene Name	heparanase
Database Link	NP_001092010 Entrez Gene 15442 MouseEntrez Gene 64537 RatEntrez Gene 10855 Human UniProt ID Q9Y251
Background	Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition; this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	HPA; HPA1; HPR1; HPSE1; HSE1
Reference Data
Protein Families	Secreted Protein
Protein Pathways	Glycosaminoglycan degradation, Metabolic pathways

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