BMPR2 Rabbit Polyclonal Antibody

CAT#: TA323211S

Anti-BMPR2 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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经常一起买 (3)
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Recombinant protein of human bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2), 20 µg
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CNY 2,900.00
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Transient overexpression lysate of bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)
    • 100 ug

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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human brain
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from C terminal 250 amino acids of human bone morphogenetic protein receptor, type II (serine/threonine kinase)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name bone morphogenetic protein receptor type 2
Background This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs; which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors; but they require their respective type I receptors for signaling; whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension; both familial and fenfluramine-associated; and with pulmonary venoocclusive disease.
Synonyms BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
Reference Data
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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