CLDN19 Rabbit Polyclonal Antibody

CAT#: TA322028

Anti-CLDN19 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

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Recombinant protein of human claudin 19 (CLDN19), transcript variant 1, 100 µg
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Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human liver cancer
Predicted cell location: Cell membrane
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 186-200 amino acids of Human Claudin 19
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 23 kDa
Gene Name claudin 19
Background The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space; through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia; hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars; macular colobomata; significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms HOMG5
Reference Data
Protein Families Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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