TCP1 beta (CCT2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Pig, Rabbit, Chimpanzee, Rhesus Monkey, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot ID#P78371)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	58 kDa
Gene Name	chaperonin containing TCP1 subunit 2
Database Link	NP_006422 Entrez Gene 12461 MouseEntrez Gene 10576 Human UniProt ID P78371
Background	This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized. [provided by RefSeq]
Synonyms	99D8.1; CCT-beta; CCTB; HEL-S-100n; PRO1633; TCP-1-beta
Note	Seq homology of immunogen across species: Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Chimpanzee (100%)
Reference Data
Protein Families	Druggable Genome

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